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    Article

    The microRNA-1278/SHP-1/STAT3 pathway is involved in airway smooth muscle cell proliferation in a model of severe asthma both intracellularly and extracellularly

    This study investigated the regulatory effects of microRNA-1278 (miR-1278) on airway inflammation, airway reconstruction, and the proliferation and apoptosis of airway smooth muscle cells (ASMCs) induced by tr...

    Jie Li, Rongchang Chen, Yongzhen Lu, Yuwei Zeng in Molecular and Cellular Biochemistry (2022)

  2. Article

    Open Access

    Hypoxic stress suppresses lung tumor-secreted exosomal miR101 to activate macrophages and induce inflammation

    Hypoxia promotes inflammation in the tumor microenvironment. Although hypoxia-inducible factor 1α (HIF1α) is a master modulator of the response to hypoxia, the exact mechanisms through which HIF1α regulates th...

    Jie Li, Peng Xu, Di Wu, Minjie Guan, Xuanwen Weng, Yongzhen Lu in Cell Death & Disease (2021)