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Clinical features, treatment, and outcomes of cavernous sinus dural arteriovenous fistulas: a cohort study of 141 patients
The cavernous sinus (CS) region is a common region of dural arteriovenous fistula (DAVF). Over time, treatment strategies are gradually changing. In this study, we present our center's experience in managing C...
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Article
Chinese characters carry special anatomical connotations
In the domain of anatomy, some Chinese characters in anatomical terms possess distinctive morphological significance. Chinese characters evolved from pictographic characters, with some of these pictographs bei...
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Article
LH-Nts Neurons Regulate VTA Calcium Dynamics Via Releasing GABA and Nts
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Open AccessTau Accumulation in the Spinal Cord Contributes to Chronic Inflammatory Pain by Upregulation of IL-1β and BDNF
Microtubule-associated protein Tau is responsible for the stabilization of neuronal microtubules under normal physiological conditions. Much attention has been focused on Tau’s contribution to cognition, but l...
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Sudden lower extremity weakness caused by an isolated sinus intracranial dural arteriovenous fistula
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A case report of dural arteriovenous fistula with concomitant petroclival meningioma: clinical implications
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Open AccessCortical thickness and white matter microstructure predict freezing of gait development in Parkinson’s disease
The clinical applications of the association of cortical thickness and white matter fiber with freezing of gait (FoG) are limited in patients with Parkinson’s disease (PD). In this retrospective study, using w...
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Article
6-Gingerol via overexpression of miR-322-5p impede lipopolysaccharide-caused inflammatory response in RAW264.7 cells
Acute lung injury (ALI) and sepsis are complicated syndromes that are often left untreated in critically ill patients. 6-Gingerol is a phenolic phytochemical compound that is found in fresh ginger, has pharmac...
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Article
Extended nonnegative matrix factorization for dynamic functional connectivity analysis of fMRI data
Dynamic functional connectivity (DFC) analysis using functional magnetic resonance imaging (fMRI) technology has attracted increasing attention in revealing brain dynamics in recent years. Although the nonnega...
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A retrospective study of 78 adult tentorial middle line region dural arteriovenous fistulae
Dural arteriovenous fistulae (DAVF) in the tentorial middle line region are uncommon with specific features and more cognitive disorders than any other region. The purpose of this study is to present clinical ...
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Discrepancy of synaptic and microtubular protein phosphorylation in the hippocampus of APP/PS1 and MAPT×P301S transgenic mice at the early stage of Alzheimer’s disease
Alzheimer’s disease (AD) is the most common neurodegenerative disorder, and is caused by multiple pathological factors, such as the overproduction of β-amyloid (Aβ) and the hyperphosphor...
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Neuronal Mechanisms Govern Glioblastoma Cell Invasion
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Sodium-Calcium Exchanger-3 Plays Critical Roles in Pain “Wind-up”
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Open AccessThe reciprocal interactions between microglia and T cells in Parkinson’s disease: a double-edged sword
In Parkinson's disease (PD), neurotoxic microglia, Th1 cells, and Th17 cells are overactivated. Overactivation of these immune cells exacerbates the disease process and leads to the pathological development of...
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Open AccessA systematic review and meta-analysis of inflammatory biomarkers in Parkinson’s disease
Neuroinflammation plays a crucial role in the pathogenesis of Parkinson’s disease (PD), but controversies persist. Studies reporting concentrations of blood or cerebrospinal fluid (CSF) markers for patients wi...
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Semi-Automated Quantitative Evaluation of Neuron Developmental Morphology In Vitro Using the Change-Point Test
Neuron morphology gives rise to distinct axons and dendrites and plays an essential role in neuronal functionality and circuit dynamics. In rat hippocampal neurons, morphological development occurs over roughl...
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Open AccessFreezing of gait is a risk factor for cognitive decline in Parkinson’s disease
Freezing of gait (FOG) and cognitive impairment are serious symptoms of Parkinson’s disease (PD). Understanding the association between FOG and cognition may help formulate specific interventions for PD indivi...
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An Empathic Pain-Regulated Neural Circuit
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Open AccessHuman loss-of-function variants in the serotonin 2C receptor associated with obesity and maladaptive behavior
Serotonin reuptake inhibitors and receptor agonists are used to treat obesity, anxiety and depression. Here we studied the role of the serotonin 2C receptor (5-HT2CR) in weight regulation and behavior. Using exom...
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Publisher Correction: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice