25 Result(s)
within
Yizheng Zhang
Life Sciences
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Article
Open AccessGenome-wide identification and structural analysis of the BMP gene family in Triplophysa dalaica
Bone morphogenetic proteins (BMPs) are part of the transforming growth factor beta (TGF-β) superfamily and play crucial roles in bone development, as well as in the formation and maintenance of various organs. Tr...
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Open AccessGINv2.0: a comprehensive topological network integrating molecular interactions from multiple knowledge bases
Knowledge bases have been instrumental in advancing biological research, facilitating pathway analysis and data visualization, which are now widely employed in the scientific community. Despite the establishme...
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Article
Open AccessTargeting AKT induced Ferroptosis through FTO/YTHDF2-dependent GPX4 m6A methylation up-regulating and degradating in colorectal cancer
Ferroptosis is a new type of iron-dependent programmed cell death induced by lipid peroxidation. However, the underlying mechanisms and function in tumor therapy still remain undisclosed especially in post-tra...
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Open AccessInhibition of AKT induces p53/SIRT6/PARP1-dependent parthanatos to suppress tumor growth
Targeting AKT suppresses tumor growth through inducing apoptosis, however, during which whether other forms of cell death occurring is poorly understood.
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Open AccessTargeting ERK induced cell death and p53/ROS-dependent protective autophagy in colorectal cancer
In recent years, many studies have shown that autophagy plays a vital role in the resistance of tumor chemotherapy. However, the interaction between autophagy and cell death has not yet been clarified. In this...
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Open AccessSNP rs12982687 affects binding capacity of lncRNA UCA1 with miR-873-5p: involvement in smoking-triggered colorectal cancer progression
This investigation was arranged to elucidate whether single nucleotide polymorphisms (SNPs) of lncRNA UCA1 was implicated in elevating colorectal cancer (CRC) risk by interacting with environmental exposures.
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Transcriptome analysis reveals the effects of grafting on sweetpotato scions during the full blooming stages
Sweetpotato (Ipomoea batatas) is a hexaploid plant and generally most genotypes do not flower at all in sub-tropics. Heterografting was carried out between sweetpotato cultivar ‘Xushu 18’ and Japanese morning glo...
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Open AccessThe wild sweetpotato (Ipomoea trifida) genome provides insights into storage root development
Sweetpotato (Ipomoea batatas (L.) Lam.) is the seventh most important crop in the world and is mainly cultivated for its underground storage root (SR). The genetic studies of this species have been hindered by a ...
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De novo transcriptome assembly of Ipomoea nil using Illumina sequencing for gene discovery and SSR marker identification
Ipomoea nil is widely used as an ornamental plant due to its abundance of flower color, but the limited transcriptome and genomic data hinder research on it. Using illumina platform, tran...
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Article
Open AccessOptimal assembly strategies of transcriptome related to ploidies of eukaryotic organisms
Several de novo transcriptome assemblers have been developed recently to assemble the short reads generated from the next-generation sequencing platforms and different strategies were employed for assembling tran...
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Article
Identification and characterization of a multi-domain sulfurtransferase in Phanerochaete chrysosporium
A sulfurtransferase gene (PcSft) with a coding region of 546 bp was cloned from the filamentous white-rot fungus Phanerochaere chrysosporium. The 181-amino acid protein contains a highly conserved “Rhodanese-like...
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Article
Characterization of lipopolysaccharide transport protein complex
Lipopolysaccharide (LPS) is an essential component of the outer membranes (OM) of most Gram-negative bacteria, which plays a crucial role in protection of the bacteria from toxic compounds and harsh conditions...
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Open AccessCharacterization and expression of Rubisco activase genes in Ipomoea batatas
Two-dimensional electrophoresis, coupled with MALDI-TOF-MS, was used to identify differentially expressed proteins between young and mature leaves of sweet potato [Ipomoea batatas (L.) Lam]. The results showed th...
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Article
Expression of the Arabidopsis vacuolar H+-pyrophosphatase gene AVP1 in peanut to improve drought and salt tolerance
The Arabidopsis gene AVP1 encodes an H+-pyrophosphatase that functions as a proton pump at the vacuolar membranes, generating a proton gradient across vacuolar membranes, which serves as the driving force for man...
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A proteomic analysis of storage stress responses in Ipomoea batatas (L.) Lam. tuberous root
During post-harvest storage, tuberous roots of sweet potato (Ipomoea batatas L. Lam.) usually undergo a biotic and abiotic stress influencing protein expression pattern and substance contents. This research compa...
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Article
A mouse protein interactome through combined literature mining with multiple sources of interaction evidence
Protein–protein interactions (PPIs) play crucial roles in a number of biological processes. Recently, protein interaction networks (PINs) for several model organisms and humans have been generated, but few lar...
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Article
Cloning and characterization of the Rubisco activase gene from Ipomoea batatas (L.) Lam
A full-length cDNA of Rubisco activase (IBrcaI) was cloned from sweet potato (Ipomoea batatas (L.) Lam) using Rapid-Amplification of cDNA Ends (RACE). IBrcaI contains a 1,347 bp open reading frame encoding a prot...
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Article
Cloning, sequence analysis and expression of bacterial lipase-coding DNA fragments from environment in Escherichia coli
Thirteen pairs of primers were designed, synthesized and used to clone the whole coding sequences or mature peptide-coding sequences of lipases. Bacteria producing extracellular lipases were enriched for the e...
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Gene expression analysis of Phanerochaete chrysosporium during the transition time from primary growth to secondary metabolism
In order to identify the secondary metabolism-related genes of Phanerochaete chrysosporium growing under pure O2 and nitrogen-limited conditions, 2322 ESTs fragments originated from two suppression-subtractive li...
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Identification and characterization of differentially expressed genes involved in pharmacological activities of roots of Panax notoginseng during plant growth
Panax notoginseng is a highly valued Chinese medicinal herb. To understand the molecular mechanism of the much higher pharmacological activities of roots of 3-year-old plants over 1-year-...
