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    Article

    Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer’s disease

    Microglial involvement in Alzheimer’s disease (AD) pathology has emerged as a risk-determining pathogenic event. While apolipoprotein E (APOE) is known to modify AD risk, it remains unclear how microglial apoE im...

    Chia-Chen Liu, Na Wang, Yuanxin Chen, Yasuteru Inoue, Francis Shue in Nature Immunology (2023)

  2. Article

    Open Access

    APOE deficiency impacts neural differentiation and cholesterol biosynthesis in human iPSC-derived cerebral organoids

    The apolipoprotein E (APOE) gene is the strongest genetic risk factor for Alzheimer’s disease (AD); however, how it modulates brain homeostasis is not clear. The apoE protein is a major lipid carrier in the brain...

    **g Zhao, Tadafumi C. Ikezu, Wenyan Lu, Jesse R. Macyczko in Stem Cell Research & Therapy (2023)

  3. Article

    Open Access

    Network structure of mobile phone addiction and anxiety symptoms among rural Chinese adolescents

    The incidence of mobile phone addiction among adolescents in rural areas of China is increasing year by year, and has already exceeded that of some cities. And phone addiction increases the risk of anxiety and...

    **g**g Wang, Yunjiao Luo, Na Yan, Yuhao Wang, Blen Dereje Shiferaw in BMC Psychiatry (2023)

  4. Article

    Open Access

    Correction: Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology

    Wenhui Qiao, Yixing Chen, Jun Zhong, Benjamin J. Madden in Molecular Neurodegeneration (2023)

  5. Article

    Open Access

    Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology

    The rare p.H157Y variant of TREM2 (Triggering Receptor Expressed on Myeloid Cells 2) was found to increase Alzheimer’s disease (AD) risk. This mutation is located at the cleavage site of TREM2 extracellular domai...

    Wenhui Qiao, Yixing Chen, Jun Zhong, Benjamin J. Madden in Molecular Neurodegeneration (2023)

  6. Article

    Open Access

    Prediction of small-for-gestational-age neonates at 33–39 weeks’ gestation in China: logistic regression modeling of the contributions of second- and third-trimester ultrasound data and maternal factors

    A screening model for prediction of small-for-gestational-age (SGA) neonates (SGAp) was established by logistic regression using ultrasound data and maternal factors (MF). We aimed to evaluate the ability of S...

    Dan** Xu, **uzhen Shen, Heqin Guan, Yiyang Zhu in BMC Pregnancy and Childbirth (2022)

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    Article

    Efficient Removal of Cr(VI) from Aqueous Solution by Fe-Mn Oxide-Modified Biochar

    Removal of Cr(VI) is of great concern due to its high mobility and toxicity in the natural environment. In this study, Fe-Mn oxide-modified biochar composite (FMBC) was prepared by impregnation to remove Cr(VI...

    Yiyang Zhu, Wencan Dai, Kai Deng, Ting Pan, Zhijie Guan in Water, Air, & Soil Pollution (2020)