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Article
Open AccessEfficacy and safety of tislelizumab plus bacillus-calmette guérin with or without chemotherapy as a bladder-sparing treatment for high-risk non-muscle-invasive bladder urothelial cancer: a real-world study
Despite adequate transurethral resection of the bladder tumor (TURBT) followed by intravesical bacillus-calmette guérin (BCG), high-risk non-muscle-invasive bladder cancer (HR-NMIBC) is associated with high ra...
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Article
Characterizing the post-traumatic growth trajectory in gastric cancer survivors: a population-based longitudinal study
Post-traumatic growth can improve the quality of life of cancer survivors. The objective of this study was to investigate post-traumatic growth heterogeneity trajectory in perioperative gastric cancer survivor...
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Article
Open AccessA feasibility study of in vivo quantitative ultra-short echo time-MRI for detecting early cartilage degeneration
To explore the feasibility of Ultra-short echo time (UTE) – MRI quantitative imaging in detecting early cartilage degeneration in vivo and underlying pathological and biochemical basis.
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Article
Open AccessThe circular RNA hsa_circ_0045800 serves as a favorable biomarker in pathogenesis of sjögren's syndrome
Circular RNAs (circRNAs) play various roles in the development of many autoimmune diseases. However, their expression profiles and specific function in Sjögren's Syndrome remains largely unknown.
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Open AccessFactors influencing senior care and living preferences among older adults in Jiangsu, China: a cross-sectional survey study
As the population ages, senior care for older adults in China has become increasingly important and has attracted the attention of both government and society. This study aimed to explore preferences and influ...
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Article
Open AccessEarly Hydrogen–Oxygen Gas Mixture Inhalation in Patients with Aneurysmal Subarachnoid Hemorrhage (HOMA): study protocol for a randomized controlled trial
Aneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening neurosurgical emergency with a high mortality rate. Delayed cerebral ischemia (DCI) and cerebral vasospasm (CVS) are delayed products of early br...
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Article
Open AccessPotential prognostic value of CSF-targeted proteomics across the Alzheimer’s disease continuum
Core biomarkers for Alzheimer’s disease (AD), such as Aβ42 and tau, have demonstrated high prognostic accuracy but do not fully capture the complex pathophysiology of AD. In this study, our objective was to id...
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Article
The added value of ADC histogram in characterization of intrauterine masses
Purpose to investigate the added value of ADC histogram parameters combined with the MRI features to differentiate among the uterine sarcomas (US), endometrial carcinomas (EC) and endometrial polyps (EP).
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Article
Open AccessA scale for measuring nursing digital application skills: a development and psychometric testing study
The adoption of digitization has emerged as a new trend in the advancement of healthcare systems. To ensure high-quality care, nurses should possess sufficient skills to assist in the digital transformation of...
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Article
Open AccessRisk factors for postoperative pulmonary complications in elderly patients undergoing video-assisted thoracoscopic surgery lobectomy under general anesthesia: a retrospective study
The objective of this study is to identify and evaluate the risk factors associated with the development of postoperative pulmonary complications (PPCs) in elderly patients undergoing video-assisted thoracosco...
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Article
Open AccessTime Kinetics and prognosis roles of calcitonin after surgery for medullary thyroid carcinoma
Medullary thyroid carcinoma (MTC) is a malignant tumor with low incidence. Currently, most studies have focused on the prognostic risk factors of MTC, whatever, time kinetic and risk factors related to calcito...
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Article
Predicting systemic diseases in fundus images: systematic review of setting, reporting, bias, and models’ clinical availability in deep learning studies
Analyzing fundus images with deep learning techniques is promising for screening systematic diseases. However, the quality of the rapidly increasing number of studies was variable and lacked systematic evaluat...
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Open AccessOld people’s preference for nursing homes in East China: a discrete choice experiment
The aged people who live in nursing home are predicted to keep growing in the following decades. There are both quantitative imbalance and structural imbalance in the utilization of nursing homes in China. Thi...
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Article
Open AccessA combination of cuproptosis and lncRNAs predicts the prognosis and tumor immune microenvironment in cervical cancer
Cuproptosis induces proteotoxic stress and eventually leads to cell death. However, the relationship between cuproptosis and lncRNAs in cervical cancer has not been fully elucidated. Therefore, we aim to explo...
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Knowledge, Attitude, and Uptake of Human Papillomavirus (HPV) Vaccination among Chinese Female Adults: A National Cross-sectional Web-Based Survey Based on a Large E-commerce Platform
Human papillomavirus (HPV) vaccination is a promising step toward cervical cancer elimination. This study was conducted to investigate the knowledge, attitude, and HPV vaccine uptake among female adults in mai...
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Open AccessKnowledge, attitudes, and practices towards Kawasaki disease from caregivers of children with Kawasaki disease: a cross-sectional study
To examine the knowledge, attitudes, and practices (KAP) of caregivers of children with Kawasaki disease toward Kawasaki disease.
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Article
Open AccessFirst-line camrelizumab (a PD-1 inhibitor) plus apatinib (an VEGFR-2 inhibitor) and chemotherapy for advanced gastric cancer (SPACE): a phase 1 study
Patients with advanced gastric cancer typically face a grim prognosis. This phase 1a (dose escalation) and phase 1b (dose expansion) study investigated safety and efficacy of first-line camrelizumab plus apati...
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Article
Open AccessThe effect of corneal power on the accuracy of 14 IOL power formulas
This study evaluates the impact of corneal power on the accuracy of 14 newer intraocular lens (IOL) calculation formulas in cataract surgery. The aim is to assess how these formulas perform across different co...
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Article
Open AccessThe importance of community resources for breastfeeding
Breastfeeding has long-lasting effects on children’s cognition, behavioral, mental and physical health. Previous research shows parental characteristics (e.g., education, race/ethnicity, income level) are asso...
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Dietary inflammatory index, genetic susceptibility and risk of incident dementia: a prospective cohort study from UK biobank
Genetic factors, diet and inflammation are associated with the development of dementia. In this study, we aimed at evaluating the impact of the dietary inflammatory index (DII) scores and genetic susceptibilit...