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    Article

    AMPK role in epilepsy: a promising therapeutic target?

    Epilepsy is a complex and multifaceted neurological disorder characterized by spontaneous and recurring seizures. It poses significant therapeutic challenges due to its diverse etiology and often-refractory na...

    Yingbei Qi, Yong-mei Zhang, Ya-nan Gao, Wen-gang Chen, Ting Zhou in Journal of Neurology (2024)

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    Article

    The development and benefits of metformin in various diseases

    Metformin has been used for the treatment of type II diabetes mellitus for decades due to its safety, low cost, and outstanding hypoglycemic effect clinically. The mechanisms underlying these benefits are comp...

    Ying Dong, Yingbei Qi, Haowen Jiang, Tian Mi, Yunkai Zhang in Frontiers of Medicine (2023)

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    Article

    Revealing the Precise Role of Calretinin Neurons in Epilepsy: We Are on the Way

    Epilepsy is a common neurological disorder characterized by hyperexcitability in the brain. Its pathogenesis is classically associated with an imbalance of excitatory and inhibitory neurons. Calretinin (CR) is...

    Yingbei Qi, Heming Cheng, Yi Wang, Zhong Chen in Neuroscience Bulletin (2022)

  4. Article

    Open Access

    One-pot Synthesis of 6-Aza-chromone Derivatives Through Cascade Carbonylation-Sonogashira-Cyclization

    We developed an efficient synthesis of aza-chromones from 3-iodo-4-(1H)-pyridones and terminal acetylenes via a cascade carbonylation-Sonogashira-cyclization reaction. By controlling the use of bases, both 6-aza-...

    Gang Cheng, Yingbei Qi, **aoqian Zhou, Rong Sheng, Yong-Zhou Hu in Scientific Reports (2017)