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  1. No Access

    Article

    Synthesis and biological evaluation of novel 1,3-diphenylurea quinoxaline derivatives as potent anticancer agents

    A series of 1,3-diphenylurea quinoxaline derivatives were synthesized and characterized by 1H, 13C NMR, and HR-ESI-MS analyses. In vitro cytotoxicity of the synthesized compounds was evaluated by MTT assay agains...

    Gui-Zhen Li, **-Lin Ouyang, Zu-Yu Mo, Yao Gu, **ao-Lin Cao… in Medicinal Chemistry Research (2021)

  2. No Access

    Article

    Synthesis and antitumor properties of novel alizarin analogs

    Series of novel hybrids of alizarin and diamide scaffold (3a–3h, 7a–7h) were designed and synthesized. In vitro antitumor activities of all compounds against HepG-2, CNE, Spca-2, Hct-116, and MGC-803 cell lines ...

    Guiyang Yao, Weilong Dai, Manyi Ye, Rizhen Huang… in Medicinal Chemistry Research (2014)

  3. No Access

    Article

    Coumarin-containing aminophosphonates bridged with chiral side chain: synthesis and influence of chirality on cytotoxicity and DNA binding

    A series of novel coumarin-containing α-aminophosphonates with two chiral centers were synthesized and a single-crystal structure of compound 8g (8g′, (R)-diethyl ((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propana...

    Ya-Jun Li, Man-Yi Ye, Ri-Zhen Huang, Gui-Yang Yao… in Medicinal Chemistry Research (2014)