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  1. No Access

    Article

    CO2-mediated organocatalytic chlorine evolution under industrial conditions

    During the chlor-alkali process, in operation since the nineteenth century, electrolysis of sodium chloride solutions generates chlorine and sodium hydroxide that are both important for chemical manufacturing1–4....

    Jiarui Yang, Wen-Hao Li, Hai-Tao Tang, Ying-Ming Pan, Dingsheng Wang, Yadong Li in Nature (2023)

  2. No Access

    Article

    Electrochemically promoted N-heterocyclic carbene polymer-catalyzed cycloaddition of aldehyde with isocyanide acetate

    N-heterocyclic carbene (NHC) is a potent organic small-molecule catalyst. However, its high synthetic price and frequent use in combination with excess oxidants have limited its utilization in industrial produ...

    Chu-Hong Ou, Ying-Ming Pan, Hai-Tao Tang in Science China Chemistry (2022)

  3. No Access

    Article

    Trace amount of single-atom palladium-catalyzed selective hydrosilylation of allenes

    Using fewer catalysts to promote the chemical conversion of more substrates is the dream synthesis pursued by synthetic chemists. Achieving highly selective reactions using trace amounts (< 1 ppm) of catalysts...

    Li-** Pang, **n-Yu Li, Shi-Cheng Ren, Hong-Min Lin, Ying-Chun Wang… in Nano Research (2022)

  4. No Access

    Article

    Synthesis and biological evaluation of novel 1,3-diphenylurea quinoxaline derivatives as potent anticancer agents

    A series of 1,3-diphenylurea quinoxaline derivatives were synthesized and characterized by 1H, 13C NMR, and HR-ESI-MS analyses. In vitro cytotoxicity of the synthesized compounds was evaluated by MTT assay agains...

    Gui-Zhen Li, **-Lin Ouyang, Zu-Yu Mo, Yao Gu, **ao-Lin Cao… in Medicinal Chemistry Research (2021)

  5. No Access

    Article

    Photocatalyst-controlled and visible light-enabled selective oxidation of pyridinium salts

    This study proposes two different methods of photocatalytic-controlled and visible light-induced selective oxidation of pyridiniums with air as the terminal oxidant. The key to these transformations is to choo...

    **ang-Jun Peng, Hai-** He, Qian Liu, Kun She, Bao-Qi Zhang… in Science China Chemistry (2021)

  6. No Access

    Article

    Circulating CD8+ T-cell repertoires reveal the biological characteristics of tumors and clinical responses to chemotherapy in breast cancer patients

    CD8+ T cells are primarily cytotoxic cells that provide immunological protection against malignant cells. Considerable evidence suggests that the T-cell repertoire is closely associated with the host immune respo...

    Kai-Rong Lin, Dan-Mei Pang, Ya-Bin **, Qian Hu… in Cancer Immunology, Immunotherapy (2018)

  7. No Access

    Article

    TCR repertoire profiling of tumors, adjacent normal tissues, and peripheral blood predicts survival in nasopharyngeal carcinoma

    The T-cell immune responses in nasopharyngeal carcinoma patients have been extensively investigated recently for designing adoptive immunotherapy or immune checkpoint blockade therapy. However, the distributio...

    Ya-bin **, Wei Luo, Guo-yi Zhang, Kai-rong Lin… in Cancer Immunology, Immunotherapy (2018)

  8. No Access

    Article

    Chemical Components of the Leaves of Siraitia grosvenorii

    Li Yang, Sen Zeng, Zhen-Hong Li, Ying-Ming Pan in Chemistry of Natural Compounds (2016)

  9. No Access

    Article

    Synthesis and antitumor properties of novel alizarin analogs

    Series of novel hybrids of alizarin and diamide scaffold (3a–3h, 7a–7h) were designed and synthesized. In vitro antitumor activities of all compounds against HepG-2, CNE, Spca-2, Hct-116, and MGC-803 cell lines ...

    Guiyang Yao, Weilong Dai, Manyi Ye, Rizhen Huang… in Medicinal Chemistry Research (2014)

  10. No Access

    Article

    Coumarin-containing aminophosphonates bridged with chiral side chain: synthesis and influence of chirality on cytotoxicity and DNA binding

    A series of novel coumarin-containing α-aminophosphonates with two chiral centers were synthesized and a single-crystal structure of compound 8g (8g′, (R)-diethyl ((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propana...

    Ya-Jun Li, Man-Yi Ye, Ri-Zhen Huang, Gui-Yang Yao… in Medicinal Chemistry Research (2014)

  11. No Access

    Article

    In situ synthesis of rosin derived chiral derivatizing agents for 31P NMR assays of amine and alcohol enantiomers

    Chiral alcohols(3, 5) were synthesized in optically pure forms from easily available rosin acid in short-steps. A comprehensive protocol for the enantiomeric excess assays of mono-or di-functional-grouped chiral ...

    Qiang Wu, Gui-yang Yao, Ye Zhang… in Chemical Research in Chinese Universities (2013)

  12. No Access

    Article

    Flavonoid constituents of Euonymus fortunei

    Six flavonoid glycosides (1–6), together with three known compounds (7–9), were isolated from the 70% ethanol extract of Euonymus fortunei and identified on the basis of nuclear magnetic resonance (NMR) data, mas...

    **-Lin Ouyang, Liu-**n Wei, **an-Ming Fang… in Chemistry of Natural Compounds (2013)