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  1. No Access

    Article

    Synthesis and antitumor properties of novel alizarin analogs

    Series of novel hybrids of alizarin and diamide scaffold (3a–3h, 7a–7h) were designed and synthesized. In vitro antitumor activities of all compounds against HepG-2, CNE, Spca-2, Hct-116, and MGC-803 cell lines ...

    Guiyang Yao, Weilong Dai, Manyi Ye, Rizhen Huang… in Medicinal Chemistry Research (2014)

  2. No Access

    Article

    Synthesis, Cytotoxicity, DNA Binding, and Apoptosis of Alizarin 2-O-Side-Chain Derivatives

    Eleven new 2-O-side-chain derivatives of alizarin were synthesized via esterification, substitution, hydrolysis, or elimination reactions. The structures of all the products were confirmed by 1H NMR, MS, and elem...

    Guiyang Yao, Manyi Ye, Weilong Dai, Yingming Pan… in Chemistry of Natural Compounds (2014)