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Article
Excellent microwave-absorbing performance in nanofiber nanocomposites by biomass conversion of sodium alginate
Sodium alginate, as one of natural polymer existing in marine plants, can function as precursor of carbon-based microwave-absorbing materials with the advantages of low cost, easy degradation, and non-toxicity...
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Article
A Targeted Lipidomic Reveals CYP450-Derived Oxylipin Linked to the Inflammatory Response by Polycyclic Aromatic Hydrocarbon Exposure in Children
Polycyclic aromatic hydrocarbon (PAH) exposure is a cause of chronic inflammation. The effect of PAHs on bioactive lipid mediators involved in the inflammatory process remains largely unknown. This study measu...
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Article
Coherent variations of tropical cyclogenesis over the North Pacific and North Atlantic
The present study investigates the relationship of tropical cyclone (TC) genesis among the western North Pacific (WNP), eastern North Pacific (ENP), and tropical North Atlantic Ocean (TNA) during July–October ...
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Article
Prognostic role of SCAMP family in acute myeloid leukemia
Acute myeloid leukemia (AML) is a malignant disease of myeloid hematopoietic stem or progenitor cells characterized by abnormal proliferation of primary and immature myeloid cells in bone marrow and peripheral...
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Article
High expression of chaperonin-containing TCP1 subunit 3 may induce dismal prognosis in multiple myeloma
The prognosis role of CCT3 in MM and the possible pathways it involved were studied in our research. By analyzing ten independent datasets (including 48 healthy donors, 2220 MM, 73 MGUS, and 6 PCL), CCT3 was foun...
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Article
Prognostic significance of PAK family kinases in acute myeloid leukemia
Acute myeloid leukemia (AML) is a clonal and heterogeneous disease characterized by a myriad of genetic defects. Genetic abnormalities are powerful prognostic factors. P21-activated kinases (PAKs) are a kind o...
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Article
Overexpression of PDK2 and PDK3 reflects poor prognosis in acute myeloid leukemia
Acute myeloid leukemia (AML) is a hematological malignancy characterized by the proliferation of immature myeloid cells, with impaired differentiation and maturation. Pyruvate dehydrogenase kinase (PDK) is a p...
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Article
High IFITM3 expression predicts adverse prognosis in acute myeloid leukemia
Acute myeloid leukemia (AML) is a malignancy caused by the uncontrolled and dysregulated clonal expansion of abnormal myeloid primordial cells. In general, the prognosis of AML remains poor despite new discove...
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Article
Prognostic value of the FUT family in acute myeloid leukemia
Genetic abnormalities are more frequently viewed as prognostic markers in acute myeloid leukemia (AML) in recent years. Fucosylation, catalyzed by fucosyltransferases (FUTs), is a post-translational modificati...
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Article
Emerging agents and regimens for treatment of relapsed and refractory acute myeloid leukemia
Relapsed and refractory acute myeloid leukemia (R/R AML) has complicated pathogenesis. Its treatment is complicated, and the prognosis is poor. So far, there is no consensus on what is the optimal treatment st...
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Article
Prognostic role of DOK family adapters in acute myeloid leukemia
Acute myeloid leukemia (AML) is a genetically and clinically heterogeneous disease. Gene mutational and expressional profile can aid the identification of different prognostic subgroups. Downstream of tyrosine...
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Article
Enhanced expressions of FHL2 and iASPP predict poor prognosis in acute myeloid leukemia
iASPP is a negative regulator of the apoptotic function of p53, and it can enhance the ability of hematopoietic stem cells to self-renew and resist chemo- and radiation therapy. Recent study showed that iASPP cou...
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Article
Prognostic significance of microRNA-99a in acute myeloid leukemia patients undergoing allogeneic hematopoietic stem cell transplantation
Overexpression of microRNA-99a (miR-99a) have been associated with adverse prognosis in acute myeloid leukemia (AML). Nevertheless, whether it also predicts poor outcome in post-allogeneic hematopoietic stem c...
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Article
Mutational spectrum and prognostic stratification of intermediate-risk acute myeloid leukemia
The mutational spectrum and prognostic stratification of intermediate-risk acute myeloid leukemia (IR-AML), which accounts for a substantial number of AML, are unclear. In order to explore the prognostic signi...
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Article
Blood concentrations of lead, cadmium, mercury and their association with biomarkers of DNA oxidative damage in preschool children living in an e-waste recycling area
Reactive oxygen species (ROS)-induced DNA damage occurs in heavy metal exposure, but the simultaneous effect on DNA repair is unknown. We investigated the influence of co-exposure of lead (Pb), cadmium (Cd), a...
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Article
High PD-L1 expression predicts poor prognosis in diffuse large B-cell lymphoma
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Article
Clinical and biological implications of mutational spectrum in acute myeloid leukemia of FAB subtypes M4 and M5
The mutational spectrum and molecular characteristics of acute myelomonocytic lineage leukemia, namely acute myeloid leukemia (AML) French–American–British (FAB) subtypes M4 and M5, are largely unknown. In ord...
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Article
Open AccessImpact of urbanization on boundary layer structure in Bei**g
The Bei**g meteorological tower is located in an area of Bei**g, China, which has developed from a suburban to an inner city setting over the past 30 years. The impacts of this urbanization process on both t...