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Open AccessA contact binary satellite of the asteroid (152830) Dinkinesh
Asteroids with diameters less than about 5 km have complex histories because they are small enough for radiative torques (that is, YORP, short for the Yarkovsky–O’Keefe–Radzievskii–Paddack effect)1 to be a notabl...
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Open AccessAn AI-powered navigation framework to achieve an automated acquisition of cardiac ultrasound images
Echocardiography is an effective tool for diagnosing cardiovascular disease. However, numerous challenges affect its accessibility, including skill requirements, workforce shortage, and sonographer strain. We ...
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Open AccessNuclear localization of mitochondrial TCA cycle enzymes modulates pluripotency via histone acetylation
Pluripotent stem cells hold great promise in regenerative medicine and developmental biology studies. Mitochondrial metabolites, including tricarboxylic acid (TCA) cycle intermediates, have been reported to pl...
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Open AccessSingle-cell transcriptomics links malignant T cells to the tumor immune landscape in cutaneous T cell lymphoma
Cutaneous T cell lymphoma (CTCL) represents a heterogeneous group of non-Hodgkin lymphoma distinguished by the presence of clonal malignant T cells. The heterogeneity of malignant T cells and the complex tumor...
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Open AccessPublisher Correction: Learning interpretable cellular and gene signature embeddings from single-cell transcriptomic data
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Open AccessLearning interpretable cellular and gene signature embeddings from single-cell transcriptomic data
The advent of single-cell RNA sequencing (scRNA-seq) technologies has revolutionized transcriptomic studies. However, large-scale integrative analysis of scRNA-seq data remains a challenge largely due to unwan...
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Open AccessMotion blur invariant for estimating motion parameters of medical ultrasound images
High-quality medical ultrasound imaging is definitely concerning motion blur, while medical image analysis requires motionless and accurate data acquired by sonographers. The main idea of this paper is to esta...
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Open AccessEndoplasmic reticulum stress-related neuroinflammation and neural stem cells decrease in mice exposure to paraquat
Paraquat (PQ), a widely used herbicide, could cause neurodegenerative diseases, yet the mechanism remains incompletely understood. This study aimed to investigate the direct effect of PQ on NSC in vivo and its...
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Open AccessMelittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response
Targeted delivery of a nanovaccine loaded with a tumor antigen and adjuvant to the lymph nodes (LNs) is an attractive approach for improving cancer immunotherapy outcomes. However, the application of this tech...
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Open AccessFrequent pauses in Escherichia coli flagella elongation revealed by single cell real-time fluorescence imaging
The bacterial flagellum is a large extracellular protein organelle that extrudes from the cell surface. The flagellar filament is assembled from tens of thousands of flagellin subunits that are exported throug...
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Open AccessFull-duplex bidirectional data transmission link using twisted lights multiplexing over 1.1-km orbital angular momentum fiber
We present a full-duplex bidirectional data transmission link using twisted lights multiplexing over 1.1-km orbital angular momentum (OAM) fiber. OAM+1 and OAM−1 modes carrying 20-Gbit/s quadrature phase-shift ke...
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Open AccessDifferent gap junction-propagated effects on cisplatin transfer result in opposite responses to cisplatin in normal cells versus tumor cells
Previous work has shown that gap junction intercellular communication (GJIC) enhances cisplatin (Pt) toxicity in testicular tumor cells but decreases it in non-tumor testicular cells. In this study, these diff...