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  1. Article

    Open Access

    A contact binary satellite of the asteroid (152830) Dinkinesh

    Asteroids with diameters less than about 5 km have complex histories because they are small enough for radiative torques (that is, YORP, short for the Yarkovsky–O’Keefe–Radzievskii–Paddack effect)1 to be a notabl...

    Harold F. Levison, Simone Marchi, Keith S. Noll, John R. Spencer in Nature (2024)

  2. Article

    Open Access

    An AI-powered navigation framework to achieve an automated acquisition of cardiac ultrasound images

    Echocardiography is an effective tool for diagnosing cardiovascular disease. However, numerous challenges affect its accessibility, including skill requirements, workforce shortage, and sonographer strain. We ...

    Raska Soemantoro, Attila Kardos, Gilbert Tang, Yifan Zhao in Scientific Reports (2023)

  3. Article

    Open Access

    Nuclear localization of mitochondrial TCA cycle enzymes modulates pluripotency via histone acetylation

    Pluripotent stem cells hold great promise in regenerative medicine and developmental biology studies. Mitochondrial metabolites, including tricarboxylic acid (TCA) cycle intermediates, have been reported to pl...

    Wei Li, Qi Long, Hao Wu, Yanshuang Zhou, Lifan Duan, Hao Yuan in Nature Communications (2022)

  4. Article

    Open Access

    Single-cell transcriptomics links malignant T cells to the tumor immune landscape in cutaneous T cell lymphoma

    Cutaneous T cell lymphoma (CTCL) represents a heterogeneous group of non-Hodgkin lymphoma distinguished by the presence of clonal malignant T cells. The heterogeneity of malignant T cells and the complex tumor...

    **angjun Liu, Shanzhao **, Simeng Hu, Ruoyan Li, Haihao Pan in Nature Communications (2022)

  5. Article

    Open Access

    Publisher Correction: Learning interpretable cellular and gene signature embeddings from single-cell transcriptomic data

    Yifan Zhao, Huiyu Cai, Zuobai Zhang, Jian Tang, Yue Li in Nature Communications (2021)

  6. Article

    Open Access

    Learning interpretable cellular and gene signature embeddings from single-cell transcriptomic data

    The advent of single-cell RNA sequencing (scRNA-seq) technologies has revolutionized transcriptomic studies. However, large-scale integrative analysis of scRNA-seq data remains a challenge largely due to unwan...

    Yifan Zhao, Huiyu Cai, Zuobai Zhang, Jian Tang, Yue Li in Nature Communications (2021)

  7. Article

    Open Access

    Motion blur invariant for estimating motion parameters of medical ultrasound images

    High-quality medical ultrasound imaging is definitely concerning motion blur, while medical image analysis requires motionless and accurate data acquired by sonographers. The main idea of this paper is to esta...

    Barmak Honarvar Shakibaei Asli, Yifan Zhao, John Ahmet Erkoyuncu in Scientific Reports (2021)

  8. Article

    Open Access

    Endoplasmic reticulum stress-related neuroinflammation and neural stem cells decrease in mice exposure to paraquat

    Paraquat (PQ), a widely used herbicide, could cause neurodegenerative diseases, yet the mechanism remains incompletely understood. This study aimed to investigate the direct effect of PQ on NSC in vivo and its...

    Zhengli Yang, Yiming Shao, Yifan Zhao, Qian Li, Rui Li, Hongxi **ao in Scientific Reports (2020)

  9. Article

    Open Access

    Melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response

    Targeted delivery of a nanovaccine loaded with a tumor antigen and adjuvant to the lymph nodes (LNs) is an attractive approach for improving cancer immunotherapy outcomes. However, the application of this tech...

    **ang Yu, Yanfeng Dai, Yifan Zhao, Shuhong Qi, Lei Liu, Lisen Lu in Nature Communications (2020)

  10. Article

    Open Access

    Frequent pauses in Escherichia coli flagella elongation revealed by single cell real-time fluorescence imaging

    The bacterial flagellum is a large extracellular protein organelle that extrudes from the cell surface. The flagellar filament is assembled from tens of thousands of flagellin subunits that are exported throug...

    Ziyi Zhao, Yifan Zhao, **ang-Yu Zhuang, Wei-Chang Lo in Nature Communications (2018)

  11. Article

    Open Access

    Full-duplex bidirectional data transmission link using twisted lights multiplexing over 1.1-km orbital angular momentum fiber

    We present a full-duplex bidirectional data transmission link using twisted lights multiplexing over 1.1-km orbital angular momentum (OAM) fiber. OAM+1 and OAM−1 modes carrying 20-Gbit/s quadrature phase-shift ke...

    Shi Chen, Jun Liu, Yifan Zhao, Long Zhu, Andong Wang, Shuhui Li in Scientific Reports (2016)

  12. Article

    Open Access

    Different gap junction-propagated effects on cisplatin transfer result in opposite responses to cisplatin in normal cells versus tumor cells

    Previous work has shown that gap junction intercellular communication (GJIC) enhances cisplatin (Pt) toxicity in testicular tumor cells but decreases it in non-tumor testicular cells. In this study, these diff...

    Yuan Zhang, Liang Tao, Lixia Fan, Yuexia Peng, Kefan Yang, Yifan Zhao in Scientific Reports (2015)