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  1. Article

    Open Access

    Author Correction: Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Cyriel Sebastiaan Olie, Erik van der Wal, Domagoj Cikes, Loes Maton in Scientific Reports (2021)

  2. Article

    Open Access

    Rod pathway and cone pathway retinal dysfunction in the 5xFAD mouse model of Alzheimer’s disease

    To characterize rod- and cone-pathway function in the 5xFAD mouse model of Alzheimer’s disease (AD) using the full-field electroretinogram (ERG). Dark-adapted (DA; rod-pathway) and light-adapted (LA; cone-path...

    J. Jason McAnany, Nathanael Matei, Yi-Fan Chen, Karen Liu in Scientific Reports (2021)

  3. Article

    Open Access

    Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability

    Muscle wasting and atrophy are regulated by multiple molecular processes, including mRNA processing. Reduced levels of the polyadenylation binding protein nucleus 1 (PABPN1), a multifactorial regulator of mRNA...

    Cyriel Sebastiaan Olie, Erik van der Wal, Domagoj Cikes, Loes Maton in Scientific Reports (2020)

  4. Article

    Open Access

    Rrm2b deletion causes mitochondrial metabolic defects in renal tubules

    Renal diseases impose considerable health and economic burdens on health systems worldwide, and there is a lack of efficient methods for the prevention and treatment due to their complexity and heterogeneity. ...

    Yi-Fan Chen, I-Hsuan Lin, Yu-Ru Guo, Wei-Jun Chiu, Mai-Szu Wu in Scientific Reports (2019)

  5. Article

    Open Access

    Minoxidil is a potential neuroprotective drug for paclitaxel-induced peripheral neuropathy

    Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of cancer treatment. No medication has been shown to be effective in the treatment of CIPN. This study aims to integrate the image-base...

    Yi-Fan Chen, Li-Hsien Chen, Yu-Min Yeh, Pei-Ying Wu, Yih-Fung Chen in Scientific Reports (2017)

  6. Article

    Open Access

    Pupillary responses in non-proliferative diabetic retinopathy

    The goal of this study was to determine the extent of rod-, cone-, and melanopsin-mediated pupillary light reflex (PLR) abnormalities in diabetic patients who have non-proliferative diabetic retinopathy (NPDR)...

    Jason C. Park, Yi-Fan Chen, Norman P. Blair, Felix Y. Chau in Scientific Reports (2017)

  7. Article

    Open Access

    Revisit the Correlation between the Elastic Mechanics and Fusion of Lipid Membranes

    Membrane fusion is a vital process in key cellular events. The fusion capability of a membrane depends on its elastic properties and varies with its lipid composition. It is believed that as the composition va...

    Zih-An Fan, Kuan-Yu Tsang, Si-Han Chen, Yi-Fan Chen in Scientific Reports (2016)