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Article
Open AccessCharacterization of T-Cell receptor repertoire in immunoglobulin a nephropathy
Immunoglobulin A nephropathy (IgAN) is an autoimmune disease characterized by abnormal IgA deposition in glomerulus. Current diagnosis of IgAN still depends on renal biopsy, an invasive method that might incre...
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Article
Open AccessGlobal Economic Burden Associated with Chronic Kidney Disease: A Pragmatic Review of Medical Costs for the Inside CKD Research Programme
Chronic kidney disease (CKD) is a progressive disease of growing prevalence, posing serious concerns for global public health. While the economic burden of CKD is substantial, data on the cost of CKD is limite...
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Article
Open AccessTransitions of dialysis status and outcomes after the unplanned first dialysis: a nationwide population-based cohort study
In Taiwan, most first-time dialysis was started without the creation of an arteriovenous shunt. Here, we aimed to elucidate the transitions of dialysis status in the unplanned first dialysis patients and deter...
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Open AccessAuthor Correction: Aberrant serum parathyroid hormone, calcium, and phosphorus as risk factors for peritonitis in peritoneal dialysis patients
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Article
Open AccessSevere acute kidney disease is associated with worse kidney outcome among acute kidney injury patients
Acute kidney disease (AKD) comprises acute kidney injury (AKI). However, whether the AKD staging system has prognostic values among AKI patients with different baseline estimated glomerular filtration (eGFR) r...
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Article
Predicting 3-month and 1-year mortality for patients initiating dialysis: a population-based cohort study
Despite the continual improvements in dialysis treatments, mortality in end-stage kidney disease (ESKD) remains high. Many mortality prediction models are available, but most of them are not precise enough to ...
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Article
Sugar- and artificially-sweetened beverages and the risks of chronic kidney disease: a systematic review and dose–response meta-analysis
Consumption of sugar or artificially-sweetened beverages (SASBs) has been linked to albuminuria, decline in kidney function, and risk of chronic kidney disease (CKD). However, the results are controversial. We...
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Article
Open AccessAberrant serum parathyroid hormone, calcium, and phosphorus as risk factors for peritonitis in peritoneal dialysis patients
Identifying modifiable risk factors of peritoneal dialysis (PD)-related peritonitis is of clinical importance in patient care. Mineral bone disease (MBD) has been associated with mortality and morbidity in end...
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Article
Open AccessAssociation between regional economic status and renal recovery of dialysis-requiring acute kidney injury among critically ill patients
The association between regional economic status and the probability of renal recovery among patients with dialysis-requiring AKI (AKI-D) is unknown. The nationwide prospective multicenter study enrolled criti...
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Article
Use of mammalian target of rapamycin inhibitors in patient with autosomal dominant polycystic kidney disease: an updated meta-analysis
Mammalian target of rapamycin (mTOR) inhibitors were previously considered a potential therapy for autosomal dominant polycystic kidney disease (ADPKD), but prior studies remained controversial about their eff...
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Article
Open AccessRrm2b deletion causes mitochondrial metabolic defects in renal tubules
Renal diseases impose considerable health and economic burdens on health systems worldwide, and there is a lack of efficient methods for the prevention and treatment due to their complexity and heterogeneity. ...
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Article
Progressive multifocal leukoencephalopathy in a renal transplant patient
End-stage renal disease (ESRD) has a major impact on health and affects more than 600,000 people in the USA. The current mainstay treatments include dialysis and kidney transplantation (KT), and patients who h...
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Article
Open AccessEnterobius vermicularis infection: prevalence and risk factors among preschool children in kindergarten in the capital area, Republic of the Marshall Islands
Enterobius vermicularis (pinworm) is one of the most common human parasitic helminths, and children are the most susceptible group. Some behavioral and environmental factors may facilitate pinworm infection. In t...
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Article
Open AccessAssociation of endothelin genetic variants and hospitalized infection complications in end-stage renal disease (ESRD) patients
Infection is the second most common cause of mortality for patients with end-stage renal disease (ESRD), accompanying with immune dysfunction. Endothelin (EDN) is known to be related to inflammation; however, it ...
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Article
Open AccessA novel SNP in the 5’ regulatory region of organic anion transporter 1 is associated with chronic kidney disease
We aimed to analyze the associations of single nucleotide polymorphisms (SNP) in the 5′ regulatory region of the human organic anion transporter 1 (OAT1) gene with chronic kidney disease (CKD). A case-control ...
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Article
Open AccessAssociations of genetic variants of endothelin with cardiovascular complications in patients with renal failure
Cardiovascular (CV) complications are the main cause of death in end-stage renal disease (ESRD) patients. The high CV risks are attributable to the additive effects of multiple factors. Endothelin (EDN) is a p...
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Article
Open AccessV-J combinations of T-cell receptor predict responses to erythropoietin in end-stage renal disease patients
Anemia is common among end-stage renal disease (ESRD) patients who undergone hemodialysis. The total reduction of red blood cell (RBC) count is associated with poor prognosis in these patients. Although erythr...
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Article
Open AccessRoles of Serum Calcium, Phosphorus, PTH and ALP on Mortality in Peritoneal Dialysis Patients: A Nationwide, Population-based Longitudinal Study Using TWRDS 2005–2012
Biomarkers of chronic kidney disease-mineral and bone disorder (CKD-MBD) correlate with morbidity and mortality in dialysis patients. However, the comparative roles of each CKD-MBD biomarker remained undetermi...
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Article
Open AccessDifferent effect of hypercholesterolemia on mortality in hemodialysis patients based on coronary artery disease or myocardial infarction
Studies on the association of total cholesterol (TC) levels and mortality in hemodialysis (HD) patients demonstrated conflicting results. The differenct effect of Hypercholesterolemia on HD patients based on t...
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Article
Open AccessRisk of liver injury after α-glucosidase inhibitor therapy in advanced chronic kidney disease patients
Although α-glucosidase inhibitors (AGIs) are commonly used for controlling postprandial blood glucose, AGIs-induced liver injuries have been reported. However, the relationship between AGIs and liver injuries ...
