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Article
Open AccessCommon dietary emulsifiers promote metabolic disorders and intestinal microbiota dysbiosis in mice
Dietary emulsifiers are linked to various diseases. The recent discovery of the role of gut microbiota–host interactions on health and disease warrants the safety reassessment of dietary emulsifiers through th...
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Chapter and Conference Paper
Face-Milling Cutting Simulation of Bevel Gears Using Ring-Dexel Method
Face milling is primarily used for producing spiral bevel and hypoid gears. Over the past few decades, this cutting method has been implemented on five-axis CNC machine tools with a cutting path that has five ...
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Article
Co-printing of micro/nanostructures integrated with preconcentration to enhance protein detection
This paper reports a fabrication method that can make microstructures such as microfluidic channels and nanostructures to generate surface plasmon resonance (SPR) signals in one-step using hot embossing. We fi...
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Article
Open AccessGinger essential oil and citral ameliorates atherosclerosis in ApoE−/− mice by modulating trimethylamine-N-oxide and gut microbiota
Recently, the role of the gut microbiota in diseases, including cardiovascular disease (CVD), has gained considerable research attention. Trimethylamine-N-oxide (TMAO), which is formed during ʟ-carnitine metab...
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Article
Correction: Comparing Predictability of Non‑invasive Tools for Hepatocellular Carcinoma in Treated Chronic Hepatitis C Patients
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Article
Comparing Predictability of Non-invasive Tools for Hepatocellular Carcinoma in Treated Chronic Hepatitis C Patients
Non-invasive tools including liver stiffness measurement (LSM) or FIB-4, assessed before or after direct acting antivirals (DAA), have been suggested to predict hepatocellular carcinoma (HCC).
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Article
Open AccessImpact of chronic hepatitis on cardiovascular events among type 2 diabetes patients in Taiwan pay-for-performance program
To investigate the impact of chronic hepatitis on cardiovascular events in patients with type 2 diabetes mellitus (T2DM). This nationwide retrospective cohort study included 152,709 adult patients (> 20 years)...
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Article
Open AccessRisk factors of recurrence and distant metastasis in primary cutaneous melanoma in Taiwan
Risk factors of recurrence and distant metastasis of acral lentiginous melanoma (ALM) are of great interest for the high percentage of ALM in cutaneous melanoma in Asian populations. This single-center retrosp...
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Article
Open AccessCharacterization of TMAO productivity from carnitine challenge facilitates personalized nutrition and microbiome signatures discovery
The capability of gut microbiota in degrading foods and drugs administered orally can result in diversified efficacies and toxicity interpersonally and cause significant impact on human health. Production of a...
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Article
Open AccessImpact of Liver Cirrhosis on Incidence of Dialysis Among Patients with Type 2 Diabetes
Renal injury is a common complication of liver cirrhosis and type 2 diabetes mellitus (T2DM). The aim of this study was to analyze the association between cirrhosis and dialysis in patients with T2DM.
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Article
Open AccessA Smartphone-based Diffusometric Immunoassay for Detecting C-Reactive Protein
In this study, we developed a portable smartphone-based diffusometry for analyzing the C-reactive protein (CRP) concentration. An optimized fluorescence microscopic add-on system for a smartphone was used to i...
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Article
Open AccessCCL4 is the only predictor for non-responder in GT-1 CHC patients with favorable IL28B genotype when treated with PegIFN/RBV
Chemokines/cytokines play important roles in the pathogenesis of chronic hepatitis C (CHC). However, their clinical characteristics and implications in treatment responses to pegylated interferon plus ribaviri...
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Article
Open AccessMemory Regulatory T cells Increase Only In Inflammatory Phase of Chronic Hepatitis B Infection and Related to Galectin-9/Tim-3 interaction
CD4+Foxp3+ regulatory T cells (Tregs) are the main immune suppressors with subpopulation of inflamed-tissue related memory Tregs (mTregs) and non-related resting Treg (rTregs). Previously, Treg was proposed to be...
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Article
Open AccessA clinicopathological analysis of 153 acral melanomas and the relevance of mechanical stress
The pathogenesis of melanomas emerging in plantar surfaces remains unclear; however, mechanical stress has been reported to increase the formation of melanomas. In this study, we conducted a multicenter retros...
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Article
Open AccessIncreased EMR2 expression on neutrophils correlates with disease severity and predicts overall mortality in cirrhotic patients
Patients with liver cirrhosis are susceptible to infections with high short-term mortalities. One CD97-related EGF-TM7 molecule, EMR2 (EGF-like molecule containing mucin-like hormone receptor 2), had been show...
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Article
Open Access7th drug hypersensitivity meeting: part one
Oral Abstracts
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Article
TIRF-enhanced nanobeads’ Brownian diffusion measurements for detecting CRP in human serum
This paper reports the in situ detection of C-reactive protein (CRP) and antibody-coated nanobead interaction by measuring the variation of the Brownian diffusion of the nanobeads. The measurements are carried...
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Article
Photoactivated Metal-Oxide Gas Sensing Nanomesh by Using Nanosphere Lithography
A photoactivated ZnO nanomesh with precisely controlled dimensions and geometries is fabricated by using nanosphere lithography process. The nanomesh structures effectively increase the surface-to-volume ratio...
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Article
Open AccessAGROBEST: an efficient Agrobacterium-mediated transient expression method for versatile gene function analyses in Arabidopsis seedlings
Transient gene expression via Agrobacterium-mediated DNA transfer offers a simple and fast method to analyze transgene functions. Although Arabidopsis is the most-studied model plant with powerful genetic and gen...
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Article
Association between the characteristics of metabolic syndrome and Alzheimer’s disease
Various epidemiological studies have shown that type 2 diabetes and metabolic syndrome are highly correlated with Alzheimer’s disease (AD). Here, we sought to assess the impact of metabolic syndrome characteri...