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  1. No Access

    Article

    An encoder-decoder network for crowd counting based on multi-scale attention mechanism

    Crowd counting is a challenging computer vision task, which is widely used in video surveillance and public safety applications. With the increase of camera resolution and the complexity of crowd image, it bec...

    Hao-Hsiang Chuang, Yi-Cheng Chen, Chang Hong Lin in Multimedia Tools and Applications (2024)

  2. No Access

    Article

    Preventing viral relapse with prophylactic tenofovir in hepatitis B carriers receiving chemotherapy: a phase IV randomized study in Taiwan

    This study aimed to compare the efficacy of shorter vs. longer tenofovir disoproxil fumarate (TDF) prophylaxis in preventing hepatitis B virus (HBV) relapse in cancer patients with chronic hepatitis B (CHB) un...

    Chao-Wei Hsu, Shin-Cheh Chen, Po-Nan Wang, Hung-Ming Wang in Hepatology International (2024)

  3. Article

    Open Access

    Role of the structure order in the transport and magnetic properties of high-entropy alloy films

    The fabrication and development of high-entropy alloys (HEAs) with exceptional functionalities is a rapidly expanding field with numerous applications. When the role of entropy in HEAs is considered, the extri...

    Jia-Wei Chen, Shih-Hsun Chen, Padraic Shafer, Wen-Yen Tzeng in NPG Asia Materials (2024)

  4. No Access

    Article

    Ferroelectric transistors based on shear-transformation-mediated rhombohedral-stacked molybdenum disulfide

    To develop low-power, non-volatile computing-in-memory device using ferroelectric transistor technologies, ferroelectric channel materials with scaled thicknesses are required. Two-dimensional semiconductors, ...

    Tilo H. Yang, Bor-Wei Liang, Hsiang-Chi Hu, Fu-**ang Chen in Nature Electronics (2024)

  5. Article

    Open Access

    Long noncoding RNA SNHG16 regulates TLR4-mediated autophagy and NETosis formation in alveolar hemorrhage associated with systemic lupus erythematosus

    Dysregulated long noncoding RNA (lncRNA) expression with increased apoptosis has been demonstrated in systemic lupus erythematosus (SLE) patients with alveolar hemorrhage (AH). SNHG16, a lncRNA, can enhance pu...

    Yu-Tung Hsieh, Yi-Cheng Chen, Yu-Chi Chou, Pin‑Yu Kuo in Journal of Biomedical Science (2023)

  6. Article

    Open Access

    Upregulation of galectin-3 in influenza A virus infection promotes viral RNA synthesis through its association with viral PA protein

    Influenza is one of the most important viral infections globally. Viral RNA-dependent RNA polymerase (RdRp) consists of the PA, PB1, and PB2 subunits, and the amino acid residues of each subunit are highly con...

    Mei-Lin Yang, Yi-Cheng Chen, Chung-Teng Wang in Journal of Biomedical Science (2023)

  7. Article

    Open Access

    Hepatitis C micro-elimination through the retrieval strategy of patients lost to follow-up

    World Health Organization sets up an ambitious and attainable goal to eliminate hepatitis C (HCV) by 2030. The previous diagnosed HCV patients lost to follow-up were considered as an important target group for...

    Cheng-Jen Chen, Yung-Hsin Huang, Chao-Wei Hsu, Yi-Cheng Chen in BMC Gastroenterology (2023)

  8. Article

    Correction: Comparing Predictability of Non‑invasive Tools for Hepatocellular Carcinoma in Treated Chronic Hepatitis C Patients

    Yen-Chun Liu, Ya-Ting Cheng, Yi-Cheng Chen in Digestive Diseases and Sciences (2023)

  9. Article

    Open Access

    Tropifexor for nonalcoholic steatohepatitis: an adaptive, randomized, placebo-controlled phase 2a/b trial

    The multimodal activities of farnesoid X receptor (FXR) agonists make this class an attractive option to treat nonalcoholic steatohepatitis. The safety and efficacy of tropifexor, an FXR agonist, in a randomiz...

    Arun J. Sanyal, Patricia Lopez, Eric J. Lawitz, Kathryn J. Lucas in Nature Medicine (2023)

  10. No Access

    Article

    Comparing Predictability of Non-invasive Tools for Hepatocellular Carcinoma in Treated Chronic Hepatitis C Patients

    Non-invasive tools including liver stiffness measurement (LSM) or FIB-4, assessed before or after direct acting antivirals (DAA), have been suggested to predict hepatocellular carcinoma (HCC).

    Yen-Chun Liu, Ya-Ting Cheng, Yi-Cheng Chen in Digestive Diseases and Sciences (2023)

  11. No Access

    Article

    Advanced Liver Fibrosis Is Associated with Necroinflammatory Grade but Not Hepatic Steatosis in Chronic Hepatitis B Patients

    Patients with chronic hepatitis B (CHB) are at an increased risk of disease progression. The influence of hepatic steatosis (HS) to liver fibrosis was controversial. We aim to investigate the association betwe...

    Yi-Cheng Chen, Chao-Wei Hsu, Wen-Juei Jeng, Chun-Yen Lin in Digestive Diseases and Sciences (2021)

  12. No Access

    Article

    Evolution pattern mining on dynamic social network

    Recently, due to the popularity of social websites and apps, considerable attention has been paid to the analysis of the structure of social networks. Clearly, social networks usually evolve over time; some ne...

    Guan-Yi Jheng, Yi-Cheng Chen, Hung-Ming Liang in The Journal of Supercomputing (2021)

  13. No Access

    Article

    A collaborative filtering recommendation system with dynamic time decay

    The collaborative filtering (CF) technique has been widely utilized in recommendation systems due to the precise prediction of users' interests. Most prior CF methods adapted overall ratings to make prediction...

    Yi-Cheng Chen, Lin Hui, Tipa** Thaipisutikul in The Journal of Supercomputing (2021)

  14. Article

    Open Access

    Flexible transparent heteroepitaxial conducting oxide with mobility exceeding 100 cm2 V−1 s−1 at room temperature

    Flexible and transparent applications have become an emerging technology and have shifted to the forefront of materials science research in recent years. Transparent conductive oxide films have been applied fo...

    Chun-Hao Ma, En-Liang Chen, Yu-Hong Lai, Yi-Cheng Chen, Li Chang in NPG Asia Materials (2020)

  15. Article

    Open Access

    Impact of hepatic steatosis on treatment response in nuclesos(t)ide analogue-treated HBeAg-positive chronic hepatitis B: a retrospective study

    The impact of hepatic steatosis (HS) on treatment response following nucleos(t)ide analogue (NA) treatment for chronic hepatitis B (CHB) patients has not been clearly elucidated. We aimed to investigate the di...

    Yi-Cheng Chen, Wen-Juei Jeng, Chao-Wei Hsu, Chun-Yen Lin in BMC Gastroenterology (2020)

  16. No Access

    Article

    A GALNT14 rs9679162 genotype-guided therapeutic strategy for advanced hepatocellular carcinoma: systemic or hepatic arterial infusion chemotherapy

    Although targeted agents are recommended as the first-line treatments for advanced hepatocellular carcinoma (aHCC), systemic chemotherapy or hepatic arterial infusion chemotherapy (HAIC) are still being used i...

    Chen-Chun Lin, Chao-Wei Hsu, Yi-Cheng Chen, Ming-Ling Chang in The Pharmacogenomics Journal (2020)

  17. No Access

    Article

    A novel algorithm for mining opinion leaders in social networks

    Recently, social network analysis (SNA) has attracted researchers’ attention due to its practicability and popularity. Several mining techniques have been developed for extracting useful knowledge from users’ ...

    Yi-Cheng Chen in World Wide Web (2019)

  18. No Access

    Chapter and Conference Paper

    Simulation Analysis of Information-Based Animal Observation System

    There are many animal species have extinct from the earth because of the behavior of human being, such as killing and the change of habitat environment due to climate change, contamination and pollution, etc. ...

    Lin Hui, Yi-Cheng Chen, Kuei Min Wang, Chiao Ming Peng, Kai-Ze Weng in Frontier Computing (2019)

  19. No Access

    Chapter and Conference Paper

    Geometry and Contact Patterns of Crossed-Axes Helipoid Gears Generated by Helical Shapers

    Helipoid gears are designed and manufactured for transmitting crossed-axes motion. The purpose of this study is to analyze the tooth geometry and contact patterns of Helipoid gears generated by helical shapers...

    Yi-Cheng Chen, Yi-Tao Lin, Chia-Chang Liu in Advances in Mechanism and Machine Science (2019)

  20. Article

    Open Access

    An engineered arginine-rich α-helical antimicrobial peptide exhibits broad-spectrum bactericidal activity against pathogenic bacteria and reduces bacterial infections in mice

    The increase in the prevalence of antibiotic-resistant bacteria has become a major public health concern. Antimicrobial peptides (AMPs) are emerging as promising candidates addressing this issue. In this study...

    Chin-Hao Yang, Yi-Cheng Chen, Shih-Yi Peng, Andy Po-Yi Tsai in Scientific Reports (2018)

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