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  1. Article

    Open Access

    Antiperistaltic effect and safety of l-menthol for esophagogastroduodenoscopy in the elderly with contraindication to hyoscine-N-butylbromide

    Hyoscine-N-butylbromide (HBB) is the most used antiperistaltic agent during esophagogastroduodenoscopy (EGD). However, almost half of the elderly have a contraindication to HBB. We aimed to evaluate l-menthol’s a...

    Tsung-Chieh Yang, **-Hsien Chen, Ming-Chih Hou, Li-Ning Peng in Scientific Reports (2022)

  2. Article

    Open Access

    Longitudinal changes of frailty in 8 years: comparisons between physical frailty and frailty index

    Few studies have made longitudinal comparisons between frailty phenotype (FP) and frailty index (FI) changes. We aimed to investigate frailty status changes defined by FP and FI concurrently, and to compare th...

    An-Chun Hwang, Wei-Ju Lee, Nicole Huang, Liang-Yu Chen, Li-Ning Peng in BMC Geriatrics (2021)

  3. Article

    Open Access

    GMP-compliant fully automated radiosynthesis of [18F]FEPPA for PET/MRI imaging of regional brain TSPO expression

    Expression of translocator protein (TSPO) on the outer mitochondrial membrane of activated microglia is strongly associated with neuroinflammation. The second-generation PET ligand [18F]FEPPA specifically binds T...

    Chi-Wei Chang, Chuang-Hsin Chiu, Ming-Hsien Lin, Hung-Ming Wu in EJNMMI Research (2021)

  4. No Access

    Article

    System identification from stationary ambient response using wavelet analysis with variable modal scales

    This study used a wavelet-based technique with variable modal scales to achieve the identification of modal parameters. Combined with the correlation technique or random decrement algorithm, the stationary res...

    Chang-Sheng Lin, Ming-Hsien Lin in Archive of Applied Mechanics (2021)

  5. No Access

    Chapter and Conference Paper

    System Identification of Structures with Incomplete Modal Information

    The topic of this paper is system identification of structures conducted with consideration of incomplete modal information. A continuum structure has infinite number of degrees of freedom and an infinite numb...

    Chang-Sheng Lin, Ming-Hsien Lin in Residual Stress, Thermomechanics & Infrare… (2019)

  6. Article

    Open Access

    Dysmobility Syndrome and Risk of Mortality for Community-Dwelling Middle-Aged and Older Adults: The Nexus of Aging and Body Composition

    Dysmobility syndrome is a newly proposed concept to comprehensively consider bone-muscle-adiposity as a whole to associate with mortality and other adverse outcomes in the older adults. Little was known in Asi...

    Wei-Ju Lee, Li-Kuo Liu, An-Chun Hwang, Li-Ning Peng, Ming-Hsien Lin in Scientific Reports (2017)

  7. Article

    Open Access

    A clinicopathological analysis of 153 acral melanomas and the relevance of mechanical stress

    The pathogenesis of melanomas emerging in plantar surfaces remains unclear; however, mechanical stress has been reported to increase the formation of melanomas. In this study, we conducted a multicenter retros...

    Yi-Shuan Sheen, Yi-Hua Liao, Ming-Hsien Lin, Jau-Shiuh Chen in Scientific Reports (2017)

  8. No Access

    Article

    Monitoring Tumor Response after Liposomal Doxorubicin in Combination with Liposomal Vinorelbine Treatment Using 3′-Deoxy-3′-[18F]Fluorothymidine PET

    Surgical resection is the standard treatment for localized colorectal cancer, which is the most common type of gastrointestinal cancer. However, over 40 % cases are diagnosed metastasized and apparently inoper...

    Chun-Yi Wu, Jo-Hsin Tang, Pei-Chia Chan, Jia-Je Li in Molecular Imaging and Biology (2017)

  9. Article

    Open Access

    Subtypes of physical frailty: Latent class analysis and associations with clinical characteristics and outcomes

    Frailty is a well-recognized geriatric syndrome with various definitions and conceptual frameworks. This study aimed to use latent class analysis to discover potential subtypes of pre-frail and frail older peo...

    Li-Kuo Liu, Chao-Yu Guo, Wei-Ju Lee, Liang-Yu Chen, An-Chun Hwang in Scientific Reports (2017)

  10. No Access

    Chapter

    Visualization of Apoptosis: Annexin V Imaging

    Annexin V, a human protein with nanomolar affinity for cell membrane-bound phosphatidylserine (PS), is the most widely used conjugate for the detection of apoptosis by using the imaging modalities such as SPEC...

    Skye Hsin-Hsien Yeh, Fan-Lin Kong in Personalized Pathway-Activated Systems Ima… (2017)

  11. Article

    Open Access

    Highlighting Indication of extracorporeal membrane oxygenation in endocrine emergencies

    Extracorporeal membrane oxygenation (ECMO) has been repeatedly used to rescue patients with cardiopulmonary arrest. However, its clinical utility in endocrine emergencies remains unclear. Herein, we describe a...

    Anne Chao, Chih-Hsien Wang, Hao-Chun You, Nai-Kwoun Chou, Hsi-Yu Yu in Scientific Reports (2015)

  12. No Access

    Article

    Monitoring Tumor Response with Radiolabeled Nucleoside Analogs in a Hepatoma-Bearing Mouse Model Early After Doxisome® Treatment

    This study aims to demonstrate that 3′-deoxy-3′-18F-fluorothymidine (18F-FLT) positron emission tomography (PET) is a promising modality for noninvasively monitoring the therapeutic efficacy of Doxisome® in a sub...

    Chun-Yi Wu, Lin-Shan Chou, Pei-Chia Chan, Chung-Hsien Ho in Molecular Imaging and Biology (2013)

  13. No Access

    Chapter and Conference Paper

    Solving Unbounded Knapsack Problem Based on Quantum Genetic Algorithms

    Resource distribution, capital budgeting, investment decision and transportation question could form as knapsack question models. Knapsack problem is one kind of NP-Complete problem and Unbounded Knapsack prob...

    Rung-Ching Chen, Yun-Hou Huang in Intelligent Information and Database Syste… (2010)

  14. No Access

    Chapter

    PSO Algorithm for Primer Design

    In recent years, polymerase chain reactions (PCR) have been widely applied in medical science. The PCR technique allows a small amount of DNA to be amplified exponentially, thus ensuring that the amount of DNA...

    Ming-Hsien Lin, Yu-Huei Cheng in Trends in Intelligent Systems and Computer… (2008)

  15. No Access

    Article

    The impact of impact factor on small specialties: A case study of family medicine in Taiwan

    Ming-Hsien Lin, Liang-Kung Chen in Scientometrics (2006)