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Article
Open AccessAntiperistaltic effect and safety of l-menthol for esophagogastroduodenoscopy in the elderly with contraindication to hyoscine-N-butylbromide
Hyoscine-N-butylbromide (HBB) is the most used antiperistaltic agent during esophagogastroduodenoscopy (EGD). However, almost half of the elderly have a contraindication to HBB. We aimed to evaluate l-menthol’s a...
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Article
Open AccessLongitudinal changes of frailty in 8 years: comparisons between physical frailty and frailty index
Few studies have made longitudinal comparisons between frailty phenotype (FP) and frailty index (FI) changes. We aimed to investigate frailty status changes defined by FP and FI concurrently, and to compare th...
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Article
Open AccessGMP-compliant fully automated radiosynthesis of [18F]FEPPA for PET/MRI imaging of regional brain TSPO expression
Expression of translocator protein (TSPO) on the outer mitochondrial membrane of activated microglia is strongly associated with neuroinflammation. The second-generation PET ligand [18F]FEPPA specifically binds T...
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Article
System identification from stationary ambient response using wavelet analysis with variable modal scales
This study used a wavelet-based technique with variable modal scales to achieve the identification of modal parameters. Combined with the correlation technique or random decrement algorithm, the stationary res...
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Chapter and Conference Paper
System Identification of Structures with Incomplete Modal Information
The topic of this paper is system identification of structures conducted with consideration of incomplete modal information. A continuum structure has infinite number of degrees of freedom and an infinite numb...
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Article
Open AccessDysmobility Syndrome and Risk of Mortality for Community-Dwelling Middle-Aged and Older Adults: The Nexus of Aging and Body Composition
Dysmobility syndrome is a newly proposed concept to comprehensively consider bone-muscle-adiposity as a whole to associate with mortality and other adverse outcomes in the older adults. Little was known in Asi...
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Article
Open AccessA clinicopathological analysis of 153 acral melanomas and the relevance of mechanical stress
The pathogenesis of melanomas emerging in plantar surfaces remains unclear; however, mechanical stress has been reported to increase the formation of melanomas. In this study, we conducted a multicenter retros...
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Article
Monitoring Tumor Response after Liposomal Doxorubicin in Combination with Liposomal Vinorelbine Treatment Using 3′-Deoxy-3′-[18F]Fluorothymidine PET
Surgical resection is the standard treatment for localized colorectal cancer, which is the most common type of gastrointestinal cancer. However, over 40 % cases are diagnosed metastasized and apparently inoper...
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Article
Open AccessSubtypes of physical frailty: Latent class analysis and associations with clinical characteristics and outcomes
Frailty is a well-recognized geriatric syndrome with various definitions and conceptual frameworks. This study aimed to use latent class analysis to discover potential subtypes of pre-frail and frail older peo...
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Chapter
Visualization of Apoptosis: Annexin V Imaging
Annexin V, a human protein with nanomolar affinity for cell membrane-bound phosphatidylserine (PS), is the most widely used conjugate for the detection of apoptosis by using the imaging modalities such as SPEC...
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Article
Open AccessHighlighting Indication of extracorporeal membrane oxygenation in endocrine emergencies
Extracorporeal membrane oxygenation (ECMO) has been repeatedly used to rescue patients with cardiopulmonary arrest. However, its clinical utility in endocrine emergencies remains unclear. Herein, we describe a...
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Article
Monitoring Tumor Response with Radiolabeled Nucleoside Analogs in a Hepatoma-Bearing Mouse Model Early After Doxisome® Treatment
This study aims to demonstrate that 3′-deoxy-3′-18F-fluorothymidine (18F-FLT) positron emission tomography (PET) is a promising modality for noninvasively monitoring the therapeutic efficacy of Doxisome® in a sub...
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Chapter and Conference Paper
Solving Unbounded Knapsack Problem Based on Quantum Genetic Algorithms
Resource distribution, capital budgeting, investment decision and transportation question could form as knapsack question models. Knapsack problem is one kind of NP-Complete problem and Unbounded Knapsack prob...
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Chapter
PSO Algorithm for Primer Design
In recent years, polymerase chain reactions (PCR) have been widely applied in medical science. The PCR technique allows a small amount of DNA to be amplified exponentially, thus ensuring that the amount of DNA...
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Article
The impact of impact factor on small specialties: A case study of family medicine in Taiwan