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Chapter and Conference Paper
Coating Control on a Functional Digestion Tablet by Portable Near-Infrared Spectroscopy
Process analysis can effectively stabilize pharmaceutical quality and optimize the control of production process. This study attempted to use a portable near-infrared spectroscopy for rapid detection of a Chin...
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Article
Open AccessSex-related pharmacokinetic differences and mechanisms of metapristone (RU486 metabolite)
Metapristone is the primary metabolite of the abortifacient mifepristone (RU486), and is being developed as a safe and effective cancer metastatic chemopreventive agent for both sexes. Here, we systematically ...
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Article
Open AccessMultivalent Conjugation of Antibody to Dendrimers for the Enhanced Capture and Regulation on Colon Cancer Cells
Circulation tumor cells (CTCs) in the bloodstream of early-stage cancer patients carry the important information about valuable biomarkers and biological properties of primary tumor. However, detection and cap...
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Article
Open AccessSystems pharmacology of mifepristone (RU486) reveals its 47 hub targets and network: Comprehensive analysis and pharmacological focus on FAK-Src-Paxillin complex
Mifepristone (RU486), a synthetic steroid compound used as an abortifacient drug, has received considerable attention to its anticancer activity recently. To explore the possibility of using mifepristone as a ...
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Article
Determination of organochlorine pesticide residues in rice by gas chromatography-mass spectrometry following directly suspended droplet microextraction
A simple and efficient approach as directly suspended droplet microextraction (DSDME) was applied to the determination of organochlorine pesticides in rice prior to analysis by gas chromatography-mass spectrometr...
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Article
Synthesis, Spectral Characterization, and In Vitro Cellular Activities of Metapristone, a Potential Cancer Metastatic Chemopreventive Agent Derived from Mifepristone (RU486)
Mifepristone (RU486) is marketed and used widely by women as an abortifacient, and experimentally for psychotic depression and anticancer treatments. After administration, metapristone is found to be the most ...
