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Article
Inositol 1,4,5-trisphosphate accumulation in brain of lithium-treated rats
The mechanism of action of lithium as a drug for patients with affective disorders was investigated. Three-week-old male rats were orally administered 2.7 mEq Li2CO3/kg/d for 1 or 3 wk, and phosphatidylinositol (...
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Article
Regulation of the biosynthesis of platelet-activating factor in alveolar macrophages
Activities of enzymes which metabolize lysoplatelet-activating factor (lysoPAF) and platelet-activating factor (PAF) were studied in rabbit alveolar macrophage lysates. Substantial acetyltransferase activity w...
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Article
Production of platelet-activating factor by human normodense and hypodense eosinophils
Normodense eosinophils and neutrophils from normal donors produced considerable amounts of plateletactivating factor (PAF) when stimulated with ionophore A23187. PAF produced by eosinophils appeared to be degr...
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Article
Phospholipid analysis of human eosinophils: High levels of alkylacylglycerophosphocholine (PAF precursor)
The phospholipid composition and fatty acid profiles of human eosinophils were studied. Extremely high levels of ether phospholipids were found in this type of cell, such as alkylacylglycerophosphocholine (GPC...
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Chapter
Metabolism of Docosahexaenoic-Acid-Containing Species of Ether Phospholipid in Rat Brain
The metabolism of hexaene species of ethanolamine plasmalogen (1-alk-1’-enyl-2-acylglycero-3-phosphoethanol-amine, alkenylacyl-GPE) and 1-alkyl-2-acylglycero-3-phosphoethanolamine (alkylacyl-GPE) was studied b...
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Article
Alkenyl and alkyl ether phospholipids in pig mesenteric lymph node lymphocytes
Significant amounts of alkenyl and alkyl ether phosphoglycerides were found in pig mesenteric lymph node lymphocytes. The choline phosphoglycerides are composed of 2.6% alkenyl ether and 25.7% alkyl ether comp...