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  1. No Access

    Article

    High FDG uptake on PET is associated with negative cell-to-cell adhesion molecule E-cadherin expression in lung adenocarcinoma

    E-cadherin is a main cell-to-cell adhesion molecule. A negative expression of E-cadherin correlates with distant metastasis in lung cancer. Recently, it was reported that there is an association between FDG up...

    Kotaro Higashi, Yoshimichi Ueda, Miyako Shimasaki… in Annals of Nuclear Medicine (2017)

  2. No Access

    Article

    Correlation of HIF-1α/HIF-2α expression with FDG uptake in lung adenocarcinoma

    Hypoxia is a key element involved in the development and progression of tumors. HIF-1α may transiently induce and mediate the response to acute and severe hypoxia, while HIF-2α may induce a longer response and...

    Kotaro Higashi, Toshiaki Yamagishi, Yoshimichi Ueda… in Annals of Nuclear Medicine (2016)

  3. No Access

    Article

    VEGF-A and its isoform VEGF121 mRNA expression measured by quantitative real-time RT-PCR: correlation with F-18 FDG uptake and aggressiveness of lung adenocarcinoma: preliminary study

    To investigate the correlation of vascular endothelial growth factor (VEGF) A and its isoform VEGF 121 mRNA expression with F-18 fluorodeoxyglucose (FDG) uptake and aggressiveness in lung adenocarcinoma.

    JianFei Guo, Kotaro Higashi, Yoshimichi Ueda… in Annals of Nuclear Medicine (2011)

  4. No Access

    Article

    Assessment of VEGF-D expression measured by immunohistochemical staining and F-18 FDG uptake on PET as biological prognostic factors for recurrence in patients with surgically resected lung adenocarcinoma

    To assess whether the combined evaluation of vascular endothelial growth factor D (VEGF-D) expression and fluorodeoxyglucose (FDG) uptake correlates with lymph node metastasis and post-operative recurrence in ...

    Lina Zhang, Kotaro Higashi, Yasuhito Ishigaki… in Annals of Nuclear Medicine (2010)