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  1. Article

    Open Access

    Ebola virus–like particles reprogram cellular metabolism

    Ebola virus can trigger a release of pro-inflammatory cytokines with subsequent vascular leakage and impairment of clotting finally leading to multiorgan failure and shock after entering and infecting patients...

    Huaqi Tang, Yasmine Abouleila, Anno Saris… in Journal of Molecular Medicine (2023)

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  2. No Access

    Protocol

    Live Single-Cell Mass Spectrometry (LSC-MS) for Plant Metabolomics

    Live single-cell mass spectrometry (LSC-MS) allows for the detection of hundreds to thousands of metabolite peaks acquired from a single plant cell within a few minutes. Plant cells are first observed under a ...

    Keiko Masuda, Yasmine Abouleila, Ahmed Ali, Toshio Yanagida… in Plant Metabolomics (2018)

  3. No Access

    Chapter

    Single-Cell Metabolomics

    The dynamics of a cell is always changing. Cells move, divide, communicate, adapt, and are always reacting to their surroundings non-synchronously. Currently, single-cell metabolomics has become the leading fi...

    Samy Emara, Sara Amer, Ahmed Ali… in Metabolomics: From Fundamentals to Clinica… (2017)

  4. No Access

    Article

    Quantitative Live Single-cell Mass Spectrometry with Spatial Evaluation by Three-Dimensional Holographic and Tomographic Laser Microscopy

    The locations and volumes of the contents of a single HepG2 cell were visualized under three-dimensional (3D) holographic and tomographic (HT) laser microscopy, colored by refractive index, not staining. After...

    Ahmed Ali, Yasmine Abouleila, Sara Amer, Rie Furushima, Samy Emara… in Analytical Sciences (2016)

  5. No Access

    Article

    Direct Lipido-Metabolomics of Single Floating Cells for Analysis of Circulating Tumor Cells by Live Single-cell Mass Spectrometry

    Direct trap** of a single floating cell, i.e. a white blood cell from a drop of blood, within a nanospray tip was followed by super-sonication after the addition of ionization solvent. Molecular detection of an...

    Eiso Hiyama, Ahmed Ali, Sara Amer, Takanori Harada, Kazumi Shimamoto… in Analytical Sciences (2015)