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Article
Open AccessEvaluation of gastrin-releasing peptide receptor, prostate-specific membrane antigen, and neurotensin receptor 1 as potential biomarkers for accurate prostate cancer stratified diagnosis
Studies on single-target PET imaging of gastrin-releasing peptide receptor (GRPR), prostate-specific membrane antigen (PSMA), or neurotensin receptor 1(NTR1) have been reported. However, the performance of the...
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Article
Transcriptomic and metabolomic analyses reveal CmMYB308 as a key regulator in the pink flower color variation of ‘Dante Purple’ chrysanthemum
CmMYB308 was identified as a key regulator in chrysanthemum flower color variation from purple to pink by conducting transcriptome and metabolome analysis. CmMYB308 can inhibit anthocyanin biosynthesis by supp...
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Article
Nickel Foam-Loaded Zn/Co Bimetallic Phosphide as an Efficient Bifunctional Electrolytic Water Catalyst
A challenge persists in the creation of bifunctional electrocatalysts that are efficient, stable, and abundant for the purpose of splitting water. In this study, we successfully synthesized zinc-cobalt-phospho...
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Article
Exome sequencing reveals genetic heterogeneity and clinically actionable findings in children with cerebral palsy
Cerebral palsy (CP) is the most common motor disability in children. To ascertain the role of major genetic variants in the etiology of CP, we conducted exome sequencing on a large-scale cohort with clinical m...
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Article
Improved delay-dependent stability conditions for discrete-time neural networks with time-varying delays
This paper investigates the stability problem of discrete-time neural networks with time-varying delays. Firstly, an augmented Lyapunov–Krasovskii functional (LKF) is constructed. The augmented LKF contains ad...
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Article
Cobalt-molybdenum bimetallic phosphide grown in situ on nickel foam as a bifunctional electrocatalyst for efficient water splitting
The design of low-cost, efficient, and non-precious metal catalysts for both cathodic hydrogen evolution reaction (HER) and anodic oxygen evolution reaction (OER) in overall water splitting is a necessary and ...
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Article
Open AccessGenetic parameters, reciprocal cross differences, and age-related heterosis of egg-laying performance in chickens
Egg-laying performance is economically important in poultry breeding programs. Crossbreeding between indigenous and elite commercial lines to exploit heterosis has been an upward trend in traditional layer bre...
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Article
Hierarchical chitosan/polyvinyl alcohol/polyethylene glycol/nonwoven fabric micro/nanofiber composite membrane: a potential biomaterial for wound dressing
A hierarchical chitosan/polyvinyl alcohol/polyethylene glycol/nonwoven fabric (CS/PVA/PEG/NWF) micro/nanofiber composite membrane (CM) was prepared via electrospinning as a potential wound dressing. The polyes...
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Article
Open AccessThe mRNA-lncRNA landscape of multiple tissues uncovers key regulators and molecular pathways that underlie heterosis for feed intake and efficiency in laying chickens
Heterosis is routinely exploited to improve animal performance. However, heterosis and its underlying molecular mechanism for feed intake and efficiency have been rarely explored in chickens. Feed efficiency c...
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Article
Open AccessAntibacterial peptide PMAP-37(F34-R), expressed in Pichia pastoris, is effective against pathogenic bacteria and preserves plums
Recently, researchers have focused on the search for alternatives to conventional antibiotics. Antimicrobial peptides are small bioactive peptides that regulate immune activation and have antibacterial activit...
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Article
Targeting Peripheral μ-opioid Receptors or μ-opioid Receptor-Expressing Neurons Does not Prevent Morphine-induced Mechanical Allodynia and Anti-allodynic Tolerance
The chronic use of morphine and other opioids is associated with opioid-induced hypersensitivity (OIH) and analgesic tolerance. Among the different forms of OIH and tolerance, the opioid receptors and cell typ...
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Article
Open AccessMale sterility and hybrid breeding in soybean
Hybrid breeding can help us to meet the challenge of feeding a growing world population with limited agricultural land. The demand for soybean is expected to grow; however, the hybrid soybean is still in the p...
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Article
Low-temperature treated polypyrrole coated cotton fabrics for efficient electromagnetic interference shielding
Conductive polymer coatings have exhibited great potential for wearable electromagnetic interference (EMI) shielding fabrics. Here, we report an efficient yet simple strategy to improve EMI shielding performan...
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Article
Open AccessSystematic analysis identifies XRCC4 as a potential immunological and prognostic biomarker associated with pan-cancer
XRCC4 is a NHEJ factor identified recently that plays a vital role in repairing DNA double-stranded breaks. Studies have reported the associations between abnormal expression of XRCC4 and tumor susceptibility ...
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Article
Open AccessGIMAP7 induces oxidative stress and apoptosis of ovarian granulosa cells in polycystic ovary syndrome by inhibiting sonic hedgehog signalling pathway
Polycystic ovary syndrome (PCOS) is a gynaecological endocrine disease. The objective of the present study was to investigate the role of GTPase immunity-associated protein (GIMAP) 7 in PCOS. A PCOS rat model ...
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Article
Comparative transcriptome analysis provides insight into the important pathways and key genes related to the pollen abortion in the thermo-sensitive genic male sterile line 373S in Brassica napus L.
The thermo-sensitive genic male sterility (TGMS) system plays a key role in the production of two-line hybrids in rapeseed (Brassica napus). To uncover key cellular events and genetic regulation associated with T...
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Article
Open AccessDexmedetomidine premedication increases preoperative sedation and inhibits stress induced by tracheal intubation in adult: a prospective randomized double-blind clinical study
The aim of this prospective randomized double-blind study is to evaluate whether oral dexmedetomidine (DEX) premedication could increase sedation in order to reduce preoperative anxiety and inhibit stress resp...
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Article
Scalable synthesis of reusable Ag@NiO micro-nanosynergized composite for highly fast reduction of 4-nitrophenol
Metal/semiconductor composites are promising catalysts. In this work, the three-dimensional flowery Ag@NiO micro-nanocomposite catalyst for the highly fast reduction of 4-nitrophenol to 4-aminophenol was prepa...
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Article
Open AccessAIF Overexpression Aggravates Oxidative Stress in Neonatal Male Mice After Hypoxia–Ischemia Injury
There are sex differences in the severity, mechanisms, and outcomes of neonatal hypoxia–ischemia (HI) brain injury, and apoptosis-inducing factor (AIF) may play a critical role in this discrepancy. Based on pr...
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Article
Open AccessPoultry genetic heritage cryopreservation and reconstruction: advancement and future challenges
Poultry genetics resources, including commercial selected lines, indigenous breeds, and experimental lines, are now being irreversibly lost at an alarming rate due to multiple reasons, which further threats th...
