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Article
Relationship between the mandibular curve of Spee and the maxillary compensating curve with dentoskeletal morphology
The purpose of this cross-sectional study was to use multiple regression analysis to evaluate the relationship between the mandibular curve of Spee (COS) and the maxillary compensating curve with dentoskeletal...
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Article
Open AccessYAP/TAZ activation mediates PQ-induced lung fibrosis by sustaining senescent pulmonary epithelial cells
Paraquat (PQ) is a widely used herbicide and a common cause of poisoning that leads to pulmonary fibrosis with a high mortality rate. However, the underlying mechanisms of PQ-induced pulmonary fibrosis and whe...
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Article
Enhancement analysis of turbulent flow and heat transfer of supercritical CO2 in a static mixer with three helical blades
Supercritical CO2 has excellent flow and heat transfer characteristics, but studies are lacking on the heat transfer characteristics of static mixers using it as a working medium. To obtain the heat transfer enha...
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Article
Numerical analysis of thermal dynamics and mixing performance in the blade-type static mixers
The turbulent thermal dynamics and mixing performance of kenics static mixer (KSM), lightnin static mixer (LSM) and Q-type static mixer (QSM) were numerically simulated with uniform heat flux within the range ...
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Article
Silencing long noncoding RNA colon cancer-associated transcript-1 upregulates microRNA-34a-5p to promote proliferation and differentiation of osteoblasts in osteoporosis
Long noncoding RNAs (lncRNAs) have been revealed to be related to multiple physiological and pathology processes such as development, carcinogenesis, and osteogenesis. It is reported that lncRNAs might exert f...
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Article
Therapy-Related Pure Erythroid Leukaemia with Complex Karyotype Following Successful Treatment for Acute Promyelocytic Leukaemia
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Article
Open AccessBmi-1 alleviates adventitial fibroblast senescence by eliminating ROS in pulmonary hypertension
Pulmonary hypertension (PH) is a life-threatening progressive disease with high mortality in the elderly. However, the pathogenesis of PH has not been fully understood and there is no effective therapy to reve...
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Article
Experimental study of gas-liquid two-phase bubbly flow characteristics in a static mixer with three twisted leaves
Under the conditions of liquid phase inlet Re ranging from 9,836 to 56,206 and gas fraction a from 4.76% to 66.67%, gas-liquid two-phase bubbly flow was investigated in a static mixer with three twisted leaves...
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Article
Rapid response to a single-dose rituximab combined with bortezomib in refractory and relapsed warm autoimmune hemolytic anemia
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Article
Open AccessLose-of-Function of a Rice Nucleolus-Localized Pentatricopeptide Repeat Protein Is Responsible for the floury endosperm14 Mutant Phenotypes
The endosperm of rice (Oryza sativa) has been usually used for the study of starch synthesis. Although several related factors have been revealed, other unknown members remain to be identified, given that starch ...
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Article
Open AccessOsNHX5-mediated pH homeostasis is required for post-Golgi trafficking of seed storage proteins in rice endosperm cells
As the major storage protein in rice seeds, glutelins are synthesized at the endoplasmic reticulum (ER) as proglutelins and transported to protein storage vacuoles (PSVs) called PBIIs (Protein body IIs), where...
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Article
OsNDUFA9 encoding a mitochondrial complex I subunit is essential for embryo development and starch synthesis in rice
Loss of function of a mitochondrial complex I subunit (OsNDUFA9) causes abnormal embryo development and affects starch synthesis by altering the expression of starch synthesis-related genes and proteins.
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Article
Open AccessGenome-wide association study identifies loci and candidate genes for non-idiopathic pulmonary hypertension in Eastern Chinese Han population
Pulmonary hypertension (PH) is a rare disease characterized by proliferation and occlusion of small pulmonary arterioles, which has been associated with a high mortality rate. The pathogenesis of PH is complex...
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Article
Laminar flow and chaotic advection mixing performance in a static mixer with perforated helical segments
The laminar flow and chaotic mixing characteristics of a high-viscosity fluid in static mixers with staggered perforated helical segments were numerically investigated in the range of Re=0.1-150. The numerical...
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Article
Open AccessGenetic polymorphism and evolutionary differentiation of Eastern Chinese Han: a comprehensive and comparative analysis on KIRs
Killer cell immunoglobulin-like receptor genes, namely KIRs, cluster together within the 160 kb genomic DNA region. In this study, we used PCR-SSP approach and successfully identified the genotype of 17 KIR ge...
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Article
Quantum clustering-based weighted linear programming support vector regression for multivariable nonlinear problem
Linear programming support vector regression shows improved reliability and generates sparse solution, compared with standard support vector regression. We present the v-linear programming support vector regressi...