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Article
Open AccessAMPK activation eliminates senescent cells in diabetic wound by inducing NCOA4 mediated ferritinophagy
Diabetic wounds are one of the long-term complications of diabetes, with a disordered microenvironment, diabetic wounds can easily develop into chronic non-healing wounds, which can impose a significant burden...
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Article
Open AccessLiver metabolomics reveals potential mechanism of Jieduan-Niwan formula against acute-on-chronic liver failure (ACLF) by improving mitochondrial damage and TCA cycle
Acute-on-chronic liver failure (ACLF) is a refractory disease with high mortality, which is characterized by a pathophysiological process of inflammation-related dysfunction of energy metabolism. Jieduan-Niwan...
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Article
Open AccessDefective NCOA4-dependent ferroptosis in senescent fibroblasts retards diabetic wound healing
Cellular senescence describes a state of permanent proliferative arrest in cells. Studies have demonstrated that diabetes promotes the pathological accumulation of senescent cells, which in turn impairs cell m...
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Article
A compensation method for gyroscope random drift based on unscented Kalman filter and support vector regression optimized by adaptive beetle antennae search algorithm
The random error of fiber optic gyroscope (FOG) is an important factor affecting its performance. In this paper, a novel and efficient compensation scheme for random drift is presented. It is a new model based...
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Article
Application of postmortem MRI for identification of medulla oblongata contusion as a cause of death: a case report
Whiplash injury is common in traffic accidents, and severe whiplash is characterized by cervical spinal cord injuries with cervical dislocation or fracture, that can be diagnosed by postmortem computed tomogra...
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Article
Open AccessBioinformatics analyses of potential ACLF biological mechanisms and identification of immune-related hub genes and vital miRNAs
Acute-on-chronic liver failure (ACLF) is a critical and refractory disease and a hepatic disorder accompanied by immune dysfunction. Thus, it is essential to explore key immune-related genes of ACLF and invest...
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Chapter and Conference Paper
Application of LSTM Neural Network in RISS/GNSS Integrated Vehicle Navigation System
The integrated navigation solution of GNSS and INS has been widely utilized in the field of land vehicle navigation. Compared with the SINS solution, the Reduced Inertial Sensor System (RISS) decreases the num...
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Article
Open AccessEpithelial differentiation of human adipose-derived stem cells (hASCs) undergoing three-dimensional (3D) cultivation with collagen sponge scaffold (CSS) via an indirect co-culture strategy
Three-dimensional (3D) cultivation with biomaterials was proposed to facilitate stem cell epithelial differentiation for wound healing. However, whether human adipose-derived stem cells (hASCs) on collagen spo...
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Chapter and Conference Paper
Real-Time Attitude Estimation for High-Speed UAV in High-Frequency Environmental Dithering Based on AMCF
Attitude Measurement System (AMS) that comprised of the low-cost Micro-Electro-Mechanical System (MEMS) based Inertial Measurement Unit (IMU) is usually used as the backup equipment for high-speed Unmanned Aer...
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Article
Compression Index versus Natural Water Content Relationshipsfor China’s Coastal Soft Clays
A large number of Cc - wn (Cc is the compression index and wn is the natural water content) correlations have been proposed by researchers for different soft clays around the world, but comparisons of these corre...
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Article
Soil Consolidation and Vacuum Pressure Distribution Under Prefabricated Vertical Drains
Vacuum preloading is an effective ground improvement technique for treating soft soils. Most previous research focused on the soil’s consolidation within the treatment depth of the prefabricated vertical drain...
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Article
Open AccessAstragaloside IV inhibits glucose-induced epithelial-mesenchymal transition of podocytes through autophagy enhancement via the SIRT–NF-κB p65 axis
Both autophagy and podocyte epithelial-mesenchymal transition (EMT) are critical factors in glomerular diseases that involve proteinuria and fibrosis. Here, we sought to determine whether plant-derived saponin...
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Article
An Enhanced IBVS Controller of a 6DOF Manipulator Using Hybrid PD-SMC Method
The accuracy and stability are two fundamental concerns of the visual servoing control system. This paper presents an enhanced image based visual servoing (IBVS) method for increasing the accuracy of a 6DOF ma...
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Article
Open AccessExosomes from high glucose-treated glomerular endothelial cells trigger the epithelial-mesenchymal transition and dysfunction of podocytes
New data indicate that abnormal glomerular endothelial cell (GEC)-podocyte crosstalk plays a critical role in diabetic nephropathy (DN). The aim of our study is to investigate the role of exosomes from high gl...
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Article
Open AccessTangluoning, a traditional Chinese medicine, attenuates in vivo and in vitro diabetic peripheral neuropathy through modulation of PERK/Nrf2 pathway
Prolonged hyperglycemia-induced oxidative stress and endoplasmic reticulum stress have been demonstrated to play a key role in progression of diabetic peripheral neuropathy (DPN). PERK/ Nrf2 pathway plays a pr...
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Article
Effect of miR-21 on Renal Fibrosis by Regulating MMP-9 and TIMP1 in kk-ay Diabetic Nephropathy Mice
MicroRNAs (miRs) play important roles in initiation and progression of many pathologic processes. However, the roles of miRs in diabetic nephropathy remain unclear. This study was to determine whether miR-21 w...
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Chapter and Conference Paper
Dynamical Research Based on a New Type of Reconfigurable Robot
Currently, the reconfigurable robot has become a hot topic for its diverse configurations. In this thesis, a new type of reconfigurable robot system is proposed, whose main modules are cylinders, which makes i...
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Chapter and Conference Paper
A Fuzzy Neural Network Based on T-S Model for Mobile Robots to Avoid Obstacles
A fuzzy neural network method based on T-S model was proposed for mobile robots to avoid obstacles. Using the proposed method, the obstacles in all environment types can be recognized, so the mobile robots cou...
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Chapter and Conference Paper
Knowledge-Based Information Extraction: A Case Study of Recognizing Emails of Nigerian Frauds
This paper describes the methodology, process and results of develo** an application ontology as software specification of the semantics of forensics in the email suspicious of Nigerian frauds. Real life exa...
