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Article
Enhancing high-efficiency breeding and microbial microdroplet cultivation techniques for Ganoderma lucidum
Ganoderma lucidum is known for its bioactive compounds, such as polysaccharides and triterpenoids, which are crucial in food and medicine. However, liquid fermentation encounters challenges in terms of strain dif...
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Article
Open AccessLncRNA SNHG26 promotes gastric cancer progression and metastasis by inducing c-Myc protein translation and an energy metabolism positive feedback loop
Metastasis is a bottleneck in cancer treatment. Studies have shown the pivotal roles of long noncoding RNAs (lncRNAs) in regulating cancer metastasis; however, our understanding of lncRNAs in gastric cancer (G...
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Article
Adjuvant sintilimab in resected high-risk hepatocellular carcinoma: a randomized, controlled, phase 2 trial
Hepatocellular carcinoma (HCC), particularly when accompanied by microvascular invasion (MVI), has a markedly high risk of recurrence after liver resection. Adjuvant immunotherapy is considered a promising ave...
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Article
Chemical Investigation of Secondary Metabolites Produced by Cordyceps Fungus Tolypocladium sp. YFCC1805002
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Article
The key technologies of Ganoderma lucidum liquid spawn preparation and scale expansion
Ganoderma lucidum possesses a variety of valuable pharmacological activities, and it has long been used to prevent and treat various human diseases. Up to now, far too little attention has been paid to the liquid...
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Article
Contrast-enhanced computed tomography radiomics and multilayer perceptron network classifier: an approach for predicting CD20+ B cells in patients with pancreatic ductal adenocarcinoma
To develop and validate a machine-learning classifier based on contrast-enhanced computed tomography (CT) for the preoperative prediction of CD20+ B lymphocyte expression in patients with pancreatic ductal adenoc...
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Article
Tolypocladium reniformisporum sp. nov. and Tolypocladium cylindrosporum (Ophiocordycipitaceae, Hypocreales) co-occurring on Ophiocordyceps sinensis
Two Tolypocladium species, Tolypocladium reniformisporum sp. nov., and T. cylindrosporum, were isolated from the sclerotium of a naturally occurring Ophiocordyceps sinensis specimen in the Baima Snow Mountains of...
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Article
Nitrogen absorption by alpine forage species based on 15N tracer technique in a hydroponic culture
Based on 15N tracer technique, absorption of different concentrations of ammonium nitrogen (N-NH4+), nitrate nitrogen (N-NO3-) and glycine (N-Gly) by root of six species of alpine forage (Puccinellia tenuiflora, ...
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Article
Machine learning for MRI radiomics: a study predicting tumor-infiltrating lymphocytes in patients with pancreatic ductal adenocarcinoma
To develop and validate a machine learning classifier based on magnetic resonance imaging (MRI), for the preoperative prediction of tumor-infiltrating lymphocytes (TILs) in patients with pancreatic ductal aden...
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Article
Influence of phosphorus on iron-based friction material prepared directly from vanadium-bearing titanomagnetite concentrates
In situ selective carbothermic reactions and vacuum sintering were used to prepare iron-based friction material directly from vanadium-bearing titanomagnetite concentrates. Effects of phosphorus addition (0.05...
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Article
Optimization of Ganoderma lucidum Polysaccharides Fermentation Process for Large-Scale Production
The objective of this study was to increase the intracellular polysaccharide yield of Ganoderma lucidum. The accordingly optimized fermentation medium by central composite design method contains glucose 40 g L−1,...
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Article
Metal-free C3-alkoxycarbonylation of quinoxalin-2(1H)-ones with carbazates as ecofriendly ester sources
Quinoxaline-3-carboxylates and analogues are prevalent key structural motifs in bioactive natural products and synthetic drugs. However, the practical protocol for preparation of these motifs from simple raw m...
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Article
Molecular dynamics simulation of the folding of single alkane chains with different lengths on single-walled carbon nanotubes and graphene
Chain folding is an important step during polymer crystallization. In order to study the effects of the surface on chain folding, molecular dynamics simulations of the folding of different alkane chains on thr...
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Article
Open AccessHepatotropic viruses as etiological agents of acute liver failure and related-outcomes among children in India: a retrospective hospital-based study
Acute liver failure (ALF) is marked by a sudden loss of hepatic function and is associated with a high mortality rate in children. The etiology of ALF is shown to vary geographically. This study assessed the f...
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Article
Theoretical investigation of the first-shell mechanism of acetylene hydration catalyzed by a biomimetic tungsten complex
The reaction mechanism of the hydration of acetylene to acetaldehyde catalyzed by [WIVO(mnt)2]2− (where mnt2− is 1,2-dicyanoethylenedithiolate) is studied using density functional theory. Both the uncatalyzed and...
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Article
Abnormal expression of NRF-2α in hepatocellular carcinoma identified with a newly prepared monoclonal antibody against human NRF-2α protein
Human nuclear respiratory factor 2 alpha subunit (NRF-2α) is fundamentally important to cell function and the development. We aimed to establish the monoclonal antibody (MAb) against the human NRF-2α protein a...
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Article
Observation on efficacy in treating active ankylosing spondylitis with integrative chinese and western medicine
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Chapter
Chronic Lymphocytic Thyroiditis in Endemic Goiter: Local Ig Production and Deposition
The local production and deposition of Ig in chronic lymphocytic thyroiditis (CLT) had been noticed long the before (1), and has been studied in detail recently., but mostly restricted to Hashimoto’s disease (...
