212 Result(s)
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Article
Effective induction of antitumor immunity by immunization with plasmid DNA encoding TRP-2 plus neutralization of TGF-β
Plasmid DNA vaccine is an appealing cancer immunotherapy. However, it is a weak immunogen and immunization with plasmid DNA encoding self-antigens, such as melanoma-associated antigens, could not induce antitu...
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Article
Real-time three-dimensional echocardiographic assessment of left ventricular remodeling index in patients with hypertensive heart disease and coronary artery disease
Left ventricular remodeling index (LVRI) was assessed in patients with hypertensive heart disease (HHD) and coronary artery disease (CAD) by real-time three-dimensional echocardiography (RT3DE). RT3DE data of ...
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Article
Vitamin D Receptor Gene Polymorphisms and the Risk of Colorectal Cancer in a Chinese Population
Objective The purpose was to investigate single nucleotide polymorphism of the vitamin D recepter gene and its possible relationship with colorectal cancer (CRC) in a Chinese population.
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Article
Expression of PADI4 in hepatocellular carcinoma
The aim of the research was to study peptidylarginine deiminase type 4 (PAD4/PADI4) expression and its tumorigenic mechanism in hepatocellular carcinomas.
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Article
Wave intensity analysis of carotid artery: A noninvasive technique for assessing hemodynamic changes of hyperthyroid patients
This study examined the wave intensity (WI) of the carotid artery in patients with hyperthyroid in order to assess the hemodynamic changes of hyperthyroid patients. A total of 86 hyperthyroid patients without ...
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Article
Open AccessMolecular ty** of mycobacterium tuberculosis isolates circulating in Jiangsu Province, China
Globally, China is the second place with high burden of tuberculosis (TB). To explore the characteristics of the pathogens of Mycobacterium tuberculosis (MTB) circulating in this area is helpful for understanding...
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Article
Higher Tacrolimus Blood Concentration Is Related to Hyperlipidemia in Living Donor Liver Transplantation Recipients
The arrival of tacrolimus has drastically improved AALDLT recipients’ survival. However, little data of tacrolimus have been reported concerning its effects on lipid metabolism for AALDLT recipients.
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Article
Open AccessA meta-analysis on the effect of corticosteroid therapy in Kawasaki disease
The current recommended therapy for Kawasaki disease (KD) is the combination of intravenous immunoglobulin (IVIG) and aspirin. However, the role of corticosteroid therapy in KD remains controversial. Using met...
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Article
Open AccessInsufficient maintenance DNA methylation is associated with abnormal embryonic development
Early pregnancy loss (EPL) is a frustrating clinical problem, whose mechanisms are not completely understood. DNA methylation, which includes maintenance methylation and de novo methylation directed by DNA methyl...
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Article
Preparation of gentamicin-loaded electrospun coating on titanium implants and a study of their properties in vitro
Implant-related infections are disastrous complications in the clinic, and there are no effective therapies. In this preliminary study, gentamicin-loaded coating on titanium implants was prepared using the ele...
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Article
Experiment on the feasibility of using modified gelatin nanoparticles as insulin pulmonary administration system for diabetes therapy
Polymeric nanoparticles are widely used as targeted carriers for biomacromolecules. In this paper, modified gelatin nanoparticles were prepared and their feasibility as insulin pulmonary administration system ...
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Article
Hyperkalemia of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers in hemodialysis: A meta-analysis
The safety of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) used in hemodialysis (HD) patients was evaluated. Medline, Embase, the Cochrane Library, some databases of...
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Article
Open AccessOutcomes of ultrasound-guided percutaneous argon-helium cryoablation of hepatocellular carcinoma
To evaluate the efficacy and safety of ultrasound (US)-guided percutaneous argon-helium cryoablation for hepatocellular carcinoma (HCC) and determine appropriate indications.
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Article
Baseline and decline of serum ADAM28 during chemotherapy of advanced non-small cell lung cancer: a probable predictive and prognostic factor
ADAM28 (a disintegrin and metalloproteinase 28) is over-expressed in non-small cell lung cancer (NSCLC) with correlation to cancer proliferation, tumor size and lymph node metastasis. In the present study, we ...
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Article
The enhanced recovery after surgery (ERAS) pathway for patients undergoing colorectal surgery: an update of meta-analysis of randomized controlled trials
This study aimed to produce a comprehensive, up-to-date meta-analysis exploring the safety and efficacy of enhanced recovery programs after colorectal resection.
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Article
Intravesical hyaluronic acid and alkalinized lidocaine for the treatment of severe painful bladder syndrome/interstitial cystitis
Intravesical instillation of hyaluronic acid (HA) may restore the integrity of glycosaminoglycan layer in patients with painful bladder syndrome/interstitial cystitis (PBS/IC), and the benefit may be improved ...
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Article
Balance of CD8+CD28+/CD8+CD28− T Lymphocytes Is Vital for Patients with Ulcerative Colitis
Immune balances are important for many diseases including ulcerative colitis (UC). This study aimed to explore the role of the balance between CD8+CD28+ and CD8+CD28− T lymphocytes for the immunological pathogene...
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Article
CD147, MMP9 expression and clinical significance of basal-like breast cancer
Our objective is to investigate the expression of CD147 and metallo-proteinase 9 (MMP9) in patients with basal-like breast cancer (BLBC) so as to determine whether these two genes may be correlated with progno...
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Article
Low expression of Beclin 1 and elevated expression of HIF-1α refine distant metastasis risk and predict poor prognosis of ER-positive, HER2-negative breast cancer
Even though ER-positive, HER2-negative breast tumors represent a subset of breast cancers with a better clinical outcome, approximately 12.7 % of patients in this subgroup ultimately develop cancer-related mor...
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Open AccessA retrospective study: platinum-based induction chemotherapy combined with gemcitabine or paclitaxel for stage IIB-IIIA central non-small-cell lung cancer
Several encouraging phase III clinical trials have evaluated platinum-based induction chemotherapy against stage IIB-IIIA non-small-cell lung cancer (NSCLC). Chemotherapy efficacy was assessed using common reg...
