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Article
A Superhydrophilic/Superhydrophobic Janus Membrane for Enhanced On-Demand Inversion Separation of Surfactant-Stabilized Water-in-Oil and Oil-in-Water Emulsions
Janus membrane materials have received widespread attention in oily wastewater due to their special wettability and high selectivity, however, the poor structural stability and weak mechanical properties of me...
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Article
Open AccessChromosomal-level genome assembly and annotation of the tropical sea cucumber Holothuria scabra
Holothuria scabra, a commercially valuable yet ecologically vulnerable tropical holothuroid, has experienced a severe decline in its wild populations, especially in China. Genomic resources are crucial for the de...
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Article
Open AccessBidirectional association between falls and multimorbidity in middle-aged and elderly Chinese adults: a national longitudinal study
This study explores the bidirectional association between multimorbidity and falls in Chinese middle-aged and elderly adults. Participants aged 45 and above from the China Health and Retirement Longitudinal St...
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Article
Association of serum osteocalcin with bone microarchitecture and muscle mass in Bei**g community-dwelling postmenopausal women
Osteoporosis is a systemic skeletal disease with increasing bone fragility and prone to fracture. Osteocalcin (OC), as the most abundant non collagen in bone matrix, has been extensively used in clinic as a bi...
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Article
Open AccessStatic charge is an ionic molecular fragment
What is static charge? Despite the long history of research, the identity of static charge and mechanism by which static is generated by contact electrification are still unknown. Investigations are challengin...
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Article
Novel 4.18 Mb deletion resulting in 2q37 microdeletion syndrome combined with PTH resistance found in one Chinese patient
2q37 microdeletion syndrome is a rare clinical condition characterized by a series of physical abnormalities. Its Albright hereditary osteodystrophy (AHO)-like manifestations and possible complication of bioch...
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Article
Open AccessAuthor Correction: Nuclear RPSA senses viral nucleic acids to promote the innate inflammatory response
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Open AccessNuclear RPSA senses viral nucleic acids to promote the innate inflammatory response
Innate sensors initiate the production of type I interferons (IFN-I) and proinflammatory cytokines to protect host from viral infection. Several innate nuclear sensors that mainly induce IFN-I production have ...
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Article
Open AccessComparative physiochemical and transcriptomic analysis reveals the influences of cross-pollination on ovary and fruit development in pummelo (Citrus maxima)
‘Shui**gmiyou’ pummelo (SJ), one of the most popular fruits in Yunnan province of China, is of relatively low fruit shape (FS) quality. In this study, we compared the FS promoting effects of cross pollination...
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Article
Open AccessSystemic and intrinsic functions of ATRX in glial cell fate and CNS myelination in male mice
Myelin, an extension of the oligodendrocyte plasma membrane, wraps around axons to facilitate nerve conduction. Myelination is compromised in ATR-X intellectual disability syndrome patients, but the causes are...
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Article
Open AccessDroplet-based high-throughput single microbe RNA sequencing by smRandom-seq
Bacteria colonize almost all parts of the human body and can differ significantly. However, the population level transcriptomics measurements can only describe the average bacteria population behaviors, ignori...
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Article
A Chinese case of CHST3-related skeletal dysplasia and a systematic review
We reported a case with carbohydrate sulfotransferase 3 (CHST3) spondyloepiphyseal dysplasia and made a systematic review of all previously reported cases.
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Article
Open AccessSolution-grown BiI/BiI3 van der Waals heterostructures for sensitive X-ray detection
X-ray detectors must be operated at minimal doses to reduce radiation health risks during X-ray security examination or medical inspection, therefore requiring high sensitivity and low detection limits. Althou...
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Article
Full-length versus intact PTH concentrations in pseudohypoparathyroidism type 1 and primary hyperparathyroidism: clinical evaluation of immunoassays in individuals from China
The application of the third-generation parathyroid hormone (PTH) assay [PTH(1–84) assay] for evaluating PTH levels in patients with pseudohypoparathyroidism type-1 (PHP1) is less popular than the second-gener...
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Article
Open AccessSerum vitamin D levels and acute kidney injury: a systemic review and meta-analysis
Numerous researches have evaluated the prevalence and clinical outcome of vitamin D deficiency in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). But the quantitative vitamin D s...
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Open AccessEffect of modified Total Body Recumbent Stepper training on exercise capacity and thioredoxin in COPD: a randomized clinical trial
Exercise intolerance is one of the major symptoms of chronic obstructive pulmonary disease (COPD). Exercise training can benefit COPD patients, but the underlying mechanism remains unclear. The modified Total ...
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Article
Open AccessNecroptosis-associated classification combined with tumor microenvironment characteristic analysis of cutaneous melanoma
Necroptosis is a mode of programmed cell death that overcomes apoptotic resistance. The accurate prognosis of cutaneous melanoma is complicated to predict due to tumor heterogeneity. Necroptosis contributes to...
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Article
A novel long-range deletion spanning CDC73 and upper-stream genes discovered in a kindred of familial primary hyperparathyroidism
To confirm the exact break-point of a novel long-range deletion discovered in one female parathyroid carcinoma (PC) patient who has a strong family history suggesting familial hyperparathyroidism, and to inves...
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Open AccessSynergistic effects of crop residue and microbial inoculant on soil properties and soil disease resistance in a Chinese Mollisol
The soil-borne disease caused by Fusarium graminearum seriously affects the corn quality. Straw can greatly improve soil quality, but the effect is limited by its nature and environmental factors. This study expl...
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Open AccessNeuron-specific chromosomal megadomain organization is adaptive to recent retrotransposon expansions
Regulatory mechanisms associated with repeat-rich sequences and chromosomal conformations in mature neurons remain unexplored. Here, we map cell-type specific chromatin domain organization in adult mouse cereb...