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Article
Association of serum osteocalcin with bone microarchitecture and muscle mass in Bei**g community-dwelling postmenopausal women
Osteoporosis is a systemic skeletal disease with increasing bone fragility and prone to fracture. Osteocalcin (OC), as the most abundant non collagen in bone matrix, has been extensively used in clinic as a bi...
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Article
Open AccessCorrection to : E-commerce food choice in the west: comparing business-to-consumer, online-to-offline food delivery service, and click and collect
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Article
Novel 4.18 Mb deletion resulting in 2q37 microdeletion syndrome combined with PTH resistance found in one Chinese patient
2q37 microdeletion syndrome is a rare clinical condition characterized by a series of physical abnormalities. Its Albright hereditary osteodystrophy (AHO)-like manifestations and possible complication of bioch...
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Article
Open AccessE-commerce food choice in the west: comparing business-to-consumer, online-to-offline food delivery service, and click and collect
This study aims to explore the significant factors driving food consumption through three e-commerce modes: Business-to-Consumer, Online-to-Offline Food Delivery Service, and Click & Collect in developed Weste...
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Chapter and Conference Paper
Application of AI Technology in Internet Finance and Analysis of Security Risks
Internet finance is a new financial market formed by the interaction of traditional financial markets and emerging financial markets. In this article, we will focus on how to use AI technology to analyze secur...
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Article
The risk of concurrent malignancies in patients with multiple endocrine neoplasia type 1: insights into clinical characteristics of those with multiple endocrine neoplasia type 1
Summarize and analyze the characteristics of patients with Multiple Endocrine Neoplasia type 1 (MEN-1) who were diagnosed with malignant tumors that do not belong to MEN-1 components.
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Article
Open AccessExplorative research on glucolipid metabolism and levels of adipokines in pseudohypoparathyroidism type 1 patients
Pseudohypoparathyroidism type 1 (PHP1) is a rare disease featuring hypocalcemia and elevated PTH level. Though disturbed calcium and phosphorus metabolism under PTH resistant have been widely studied, glucolip...
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Article
Influence of Obesity and Changes in Weight or BMI on Incident Fractures in Postmenopausal Women: From Peking Vertebral Fracture Study
This study aims to investigate the influence of overweight/obesity and change in weight or body mass index (BMI) on incident fractures among Chinese postmenopausal women. According to BMI, 754 postmenopausal w...
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Article
Open AccessCan we skip technetium-99 m sestamibi scintigraphy in pediatric primary hyperparathyroidism patients with positive neck ultrasound results?
Parathyroidectomy is the only curative treatment for primary hyperparathyroidism (PHPT). Ultrasound (US) and technetium-99 m sestamibi (99mTc-MIBI) scintigraphy are recommended as the first-line localization imag...
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Article
Incident vertebral fracture and longitudinal BMD change in Chinese postmenopausal women with early CKD: Peking Vertebral Fracture Study
Early chronic kidney disease (CKD) and non-CKD individuals had similar morphometric vertebral fracture (mVF) incidence and longitudinal bone mineral density (BMD) change. CKD did not modify the association bet...
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Article
Open AccessComparison of bone microstructure and strength in the distal radius and tibia between the different types of primary hypertrophic osteoarthropathy: an HR-pQCT study
Primary hypertrophic osteoarthropathy (PHO) is a hereditary bone disease that is grouped into PHO autosomal recessive 1 (PHOAR1) and PHO autosomal recessive 2 (PHOAR2) due to different causative genes. Data co...
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Article
A Chinese case of CHST3-related skeletal dysplasia and a systematic review
We reported a case with carbohydrate sulfotransferase 3 (CHST3) spondyloepiphyseal dysplasia and made a systematic review of all previously reported cases.
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Article
Open AccessNovel mutation in LRP5 gene cause rare osteosclerosis: cases studies and literature review
To study the effects of low-density lipoprotein receptor-related protein 5 (LRP5) gene mutations on bone, and to open up our view of LRP5 and Wnt pathways on bone mass regulation. Three patients with increased bo...
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Article
Relationships between sclerostin and morphometric vertebral fractures, bone mineral density, and bone microarchitecture in postmenopausal women
Higher sclerostin levels in postmenopausal women are associated with improved bone microarchitecture, areal and volumetric bone mineral density, and bone strength. However, the serum sclerostin level had no in...
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Article
Open AccessHealth-related quality of life of men with primary osteoporosis and its changes after bisphosphonates treatment
Osteoporosis leads to more serious consequences in men than in women, but less is known about its impacts on health-related quality of life (HRQoL) of men, and whether the anti-osteoporosis treatment can impro...
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Article
Open AccessPathogenesis and treatment of osteoporosis in patients with hemophilia
Hemophilia is a rare X-linked recessive inherited bleeding disorder caused by mutations of the genes encoding coagulation factor VIII (FVIII) or IX (FIX). Patients with hemophilia (PWH) often have a high risk ...
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Protocol
Large-Scale Complete Sequencing and Haploty** of 1–10 kb DNA Molecules Using Short Massively Parallel Reads
In this chapter, we describe a simple, low-cost method for making many copies of a single DNA molecule (1–10 kb in length) as a concatemer on a long DNA strand. This can enable applications requiring high-qual...
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Protocol
A Simple Cost-Effective Method for Whole-Genome Sequencing, Haploty**, and Assembly
In this chapter, we describe single-tube long fragment read (stLFR), a simple preparation method for whole-genome sequencing and physical haploty** based on the DNA co-barcoding strategy. Similar to LFR, stL...
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Article
Evaluation of Volumetric Bone Mineral Density, Bone Microarchitecture, and Bone Strength in Patients with Achondroplasia Caused by FGFR3 c.1138G > A Mutation
Achondroplasia (ACH) is a skeletal disorder caused by fibroblast growth factor receptor 3 (FGFR3) variants. Volumetric bone mineral density (vBMD), bone microarchitecture, and strength have not been evaluated in ...
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Article
A Novel Synonymous Variant of PHEX in a Patient with X-Linked Hypophosphatemia
X-linked dominant hypophosphatemia (XLH), the most common form of hereditary hypophosphatemic rickets/osteomalacia, is caused by loss-of-function phosphate-regulating endopeptidase homolog X-linked gene (PHEX) va...
