757 Result(s)

Article

Early change of plasma Epstein-Barr virus DNA load and the viral lytic genome level could positively predict clinical outcome in recurrent or metastatic nasopharyngeal carcinoma receiving anti-programmed cell death 1 monotherapy

Patients with recurrent or metastatic nasopharyngeal carcinoma (RM-NPC) have proven benefit from anti-programmed cell death 1 (anti-PD-1) monotherapy. Here, we retrospectively analyze the association of plasma...

Shaoyan Lin, Huaqiang Zhou, Gang Chen, **hui Xue, Qianwen Liu, Jianing Li… in BMC Cancer (2024)

Article

Serum miRNA-1 may serve as a promising noninvasive biomarker for predicting treatment response in breast cancer patients receiving neoadjuvant chemotherapy

MicroRNA-1 (miR-1) is a tumour suppressor that can inhibit cell proliferation and invasion in several cancer types. In addition, miR-1 was found to be associated with drug sensitivity. Circulating miRNAs have ...

**g Peng, Yan** Lin, **aonan Sheng, Chenwei Yuan, Yan Wang, Wen** Yin… in BMC Cancer (2024)

Article

Rapid detection of lung cancer based on serum Raman spectroscopy and a support vector machine: a case-control study

Early screening and detection of lung cancer is essential for the diagnosis and prognosis of the disease. In this paper, we investigated the feasibility of serum Raman spectroscopy for rapid lung cancer screen...

Linfang Yan, Huiting Su, Jiafei Liu, **aozheng Wen, Huaichao Luo, Yu Yin… in BMC Cancer (2024)

Article

The association between systemic immune-inflammation index and cardiotoxicity related to 5-Fluorouracil in colorectal cancer

The cardiotoxicity related to 5-Fluorouracil (5-FU) in cancer patients has garnered widespread attention. The systemic immune-inflammation index (SII) has recently been identified as a novel predictive marker ...

**aoqin Liu, Yan Wang, Wenling Wang, Hongming Dong, Gang Wang, Wanghua Chen… in BMC Cancer (2024)

Article

LMO family gene polymorphisms and Wilms tumor susceptibility in Chinese children: a five-center case-control study

Wilms tumor is the most prevalent embryonal kidney malignancy in children worldwide. Previous genome-wide association study (GWAS) identified that LIM domain only 1 (LMO1) gene polymorphisms affected the suscepti...

Wen Fu, Linqing Deng, **aosong Yan, Rui-** Hua, Jiao Zhang, Haixia Zhou… in BMC Cancer (2024)

Article

Antibiotic use during radical surgery in stage I-III colorectal cancer: correlation with outcomes?

Accumulating evidence indicates that the use of antibiotics (ATBs) in cancer patients is potentially correlated with patient prognosis. Interestingly, the use of these agents is not uncommon in colorectal canc...

Mingyue Xu, Yuanyuan Chen, Panhua Li, Qianwen Ye, Shouhan Feng, Bing Yan in BMC Cancer (2024)

Article

Targeted inhibition of DHODH is synergistic with BCL2 blockade in HGBCL with concurrent MYC and BCL2 rearrangement

High-grade B-cell lymphoma (HGBCL), the subtype of non-Hodgkin lymphoma, to be relapsed or refractory in patients after initial therapy or salvage chemotherapy. Dual dysregulation of MYC and BCL2 is one of the...

Lin Liu, Wenbin Mo, Miao Chen, Yi Qu, **** Wang, Ying Liang, **ao**g Yan in BMC Cancer (2024)

Article

Safety and efficacy of multi-target TKI combined with nivolumab in check-point inhibitor-refractory patients with advanced NSCLC: a prospective, single-arm, two-stage study

Resistance to immune checkpoint inhibitors (ICIs) represents a major unmet medical need in non-small cell lung cancer (NSCLC) patients. Vascular endothelial growth factor (VEGF) inhibition may reverse a suppre...

Bo Zhang, Hongyu Liu, Chunlei Shi, Zhiqiang Gao, Runbo Zhong, Aiqin Gu… in BMC Cancer (2024)

Article

Prediction of the axillary lymph-node metastatic burden of breast cancer by ¹⁸F-FDG PET/CT-based radiomics

The axillary lymph-node metastatic burden is closely associated with treatment decisions and prognosis in breast cancer patients. This study aimed to explore the value of ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) positron...

Yan Li, Dong Han, Cong Shen in BMC Cancer (2024)

Article

Radiomics model based on contrast-enhanced computed tomography imaging for early recurrence monitoring after radical resection of AFP-negative hepatocellular carcinoma

Although radical surgical resection is the most effective treatment for hepatocellular carcinoma (HCC), the high rate of postoperative recurrence remains a major challenge, especially in patients with alpha-fe...

Xuanzhi Yan, Yicheng Li, Wanying Qin, Jiayi Liao, Jiaxing Fan, Yu** **e… in BMC Cancer (2024)

Article

The Naples prognostic score serves as a predictor and prognostic indicator for cancer survivors in the community

Inflammation, malnutrition, and cancer are intricately interconnected. Despite this, only a few studies have delved into the relationship between inflammatory malnutrition and the risk of death among cancer su...

Chaoqun Liang, Chao Zhang, Jun Song, Lin Yan, Yun **ao, Nan Cheng, Han Wu… in BMC Cancer (2024)

Article

The mediating role of meaning in life between experiential avoidance and death anxiety among cancer patients: a cross-sectional study

Death anxiety is thought to cause a range of mental disorders among cancer patients, which may affect their mental health and even quality of life. This study sought to investigate experiential avoidance, mean...

Yixia Yan, Yongyi Chen, Meijun Ou, Youwen Gong, Renting Yang, **angyu Liu… in BMC Cancer (2024)

Article

Neoadjuvant chemotherapy followed by surgery versus concurrent chemoradiotherapy in patients with stage IIB cervical squamous cell carcinoma: a retrospective cohort study

This study aims to compare treatment outcomes between neoadjuvant chemotherapy (NACT) followed by surgery and concurrent chemoradiotherapy (CCRT) in patients with stage IIB cervical squamous cell carcinoma (CS...

**n-Bin Pan, Yan Lu, You-Sheng Wei, De-Sheng Yao in BMC Cancer (2024)

Article

Neuroendocrine carcinoma of the endometrium: a retrospective analysis of data from a single center

Neuroendocrine carcinoma (NEC) originating from the endometrium is rare, and there is limited knowledge regarding its diagnosis and optimal management. In this study, we present our experience with 11 patients...

Xueyan Liu, Yanpeng Tian, Shu** Yan, Hanlin Fu, Lulu Si, Tianjiao Lai… in BMC Cancer (2024)

Article

Systematic literature review of real-world evidence for treatments in HR+/HER2- second-line LABC/mBC after first-line treatment with CDK4/6i

Cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i) combined with endocrine therapy (ET) are currently recommended by the National Comprehensive Cancer Network (NCCN) guidelines and the European Society for M...

Veronique Lambert, Sarah Kane, Belal Howidi, Bao-Ngoc Nguyen… in BMC Cancer (2024)

Article

PTEN and P-4E-BP1 might be associated with postoperative recurrence of rectal cancer patients undergoing concurrent radiochemotherapy

Local recurrence after surgery and radiochemotherapy seriously affects the prognosis of locally advanced rectal cancer (LARC) patients. Studies on molecular markers related to the radiochemotherapy sensitivity...

Heng Zhang, **aofan Li, Wanjun Sun, Haoren Qin, Haipeng Li, Hao Yan… in BMC Cancer (2024)

Article

Correction: A chest CT-based nomogram for predicting survival in acute myeloid leukemia

** Yi, Huien Zhan, Jun Lyu, Juan Du, Min Dai, Min Zhao, Yu Zhang… in BMC Cancer (2024)

Article

WNT3 promotes chemoresistance to 5-Fluorouracil in oral squamous cell carcinoma via activating the canonical β-catenin pathway

5-Fluorouracil (5FU) is a primary chemotherapeutic agent used to treat oral squamous cell carcinoma (OSCC). However, the development of drug resistance has significantly limited its clinical application. There...

Xuyang Zhang, Kairui Sun, Ruihuan Gan, Yuxiang Yan, Chaochao Zhang… in BMC Cancer (2024)

Article

Association of serum 25-hydroxy-vitamin D concentration and risk of mortality in cancer survivors in the United States

Cancer survivors have a high risk of mortality, and vitamin D (VD) is associated with the risk of mortality. This study is aim to examine the impact of VD on mortality in cancer survivors.

**aofei Mo, Chen He, Fengfeng Han, Hui Yan, Xueqin Chen, Yuetao Wang… in BMC Cancer (2024)

Article

Ultrasound-based radiomics machine learning models for diagnosing cervical lymph node metastasis in patients with non-small cell lung cancer: a multicentre study

Cervical lymph node metastasis (LNM) is an important prognostic factor for patients with non-small cell lung cancer (NSCLC). We aimed to develop and validate machine learning models that use ultrasound radiomi...

Zhiqiang Deng, **aoling Liu, Renmei Wu, Haoji Yan, Lingyun Gou, Wenlong Hu… in BMC Cancer (2024)