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  1. Article

    Open Access

    SUMOylation of annexin A6 retards cell migration and tumor growth by suppressing RHOU/AKT1–involved EMT in hepatocellular carcinoma

    The protein annexin A6 (AnxA6) is involved in numerous membrane-related biological processes including cell migration and invasion by interacting with other proteins. The dysfunction of AnxA6, including protei...

    Yanfang Yang, Lan Huang, Nan Zhang, Ya-Nan Deng, Xu Cao… in Cell Communication and Signaling (2024)

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  2. Article

    Open Access

    SUMOylation of AnxA6 facilitates EGFR-PKCα complex formation to suppress epithelial cancer growth

    The Annexin A6 (AnxA6) protein is known to inhibit the epidermal growth factor receptor (EGFR)-extracellular signal regulated kinase (ERK)1/2 signaling upon EGF stimulation. While the biochemical mechanism of ...

    Zenghua Sheng, Xu Cao, Ya-nan Deng, **nyu Zhao… in Cell Communication and Signaling (2023)

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  3. Article

    Open Access

    A wheat resistosome defines common principles of immune receptor channels

    Plant intracellular nucleotide-binding leucine-rich repeat receptors (NLRs) detect pathogen effectors to trigger immune responses1. Indirect recognition of a pathogen effector by the dicotyledonous Arabidopsis th...

    Alexander Förderer, Ertong Li, Aaron W. Lawson, Ya-nan Deng, Yue Sun… in Nature (2022)

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  4. No Access

    Article

    A magnetic adsorbent grafted with pendant naphthyl polymer brush for enrichment of the nonsteroidal anti-inflammatory drugs indomethacin and diclofenac

    Poly(2-naphthyl acrylate) was first grafted onto silica-coated magnetic nanoparticles by surface-initiated atom transfer radical polymerization to prepare a reversed-phase magnetic adsorbent. The resulting pol...

    Ya’nan Deng, Jiwei Shen, Jiawei Liu, Yinmao Wei, Chaozhan Wang in Microchimica Acta (2018)

  5. No Access

    Article

    Preparation of a boronate affinity material with ultrahigh binding capacity for cis-diols by grafting polymer brush from polydopamine-coated magnetized graphene oxide

    Poly(3-acrylamidophenylboronic acid) (PAAPBA) was grafted onto polydopamine-coated magnetic graphene oxide via surface-initiated atom transfer radical polymerization to obtain a new kind of boronate affinity m...

    Ya’nan Deng, Qin Gao, Juan Ma, Chaozhan Wang, Yinmao Wei in Microchimica Acta (2018)

  6. No Access

    Article

    A novel heterozygous NR1H4 termination codon mutation in idiopathic infantile cholestasis

    This study aimed to evaluate the genetic effect of the NR1H4 gene in the pathogenesis of idiopathic infantile cholestasis of Chinese subjects in Guangxi, China.

    **u-Qi Chen, Lin-Lin Wang, Qing-Wen Shan, Qing Tang… in World Journal of Pediatrics (2012)