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  1. Article

    Open Access

    A Major Hydrothermal Reservoir Underneath the Tatun Volcano Group of Taiwan: Clues from a Dense Linear Geophone Array

    A dense linear geophone array is deployed across the Tatun volcano group (TVG) at the northern tip of Taiwan, where more than 7 million residents live in the Taipei metropolis. The array is composed of 50 geop...

    C. H. Lin, Y. C. Lai, M. H. Shih, C. J. Lin, J. S. Ku in Pure and Applied Geophysics (2020)

  2. Article

    Open Access

    Active Volcanism Revealed from a Seismicity Conduit in the Long-resting Tatun Volcano Group of Northern Taiwan

    Abundant earthquakes clustered within a particular zone often reflect an active geological feature, such as clustering seismicity along a fault zone and a huge number of volcanic-earthquakes around the eruptin...

    H. C. Pu, C. H. Lin, Y. C. Lai, M. H. Shih, L. C. Chang, H. F. Lee in Scientific Reports (2020)

  3. Article

    Open Access

    The effect of orbital-lattice coupling on the electrical resistivity of YBaCuFeO5 investigated by X-ray absorption

    Temperature-dependent X-ray absorption near-edge structures, X-ray linear dichroism (XLD) and extended X-ray absorption fine structure (EXAFS) spectroscopic techniques were used to investigate the valence stat...

    M. K. Srivastava, X.-S. Qiu, Y. Y. Chin, S. H. Hsieh, Y. C. Shao in Scientific Reports (2019)

  4. Article

    Open Access

    Therapeutic glucocorticoids prevent bone loss but drive muscle wasting when administered in chronic polyarthritis

    Patients with rheumatoid arthritis (RA) experience extra-articular manifestations including osteoporosis and muscle wasting, which closely associate with severity of disease. Whilst therapeutic glucocorticoids...

    C. G. Fenton, J. M. Webster, C. S. Martin, S. Fareed in Arthritis Research & Therapy (2019)

  5. Article

    Open Access

    Spin-charge-lattice coupling in YBaCuFeO5: Optical properties and first-principles calculations

    We combined spectroscopic ellipsometry, Raman scattering spectroscopy, and first-principles calculations to explore the optical properties of YBaCuFeO5 single crystals. Measuring the optical absorption spectrum o...

    H. W. Chen, Y.-W. Chen, J.-L. Kuo, Y. C. Lai, F. C. Chou, C. H. Du in Scientific Reports (2019)

  6. No Access

    Article

    Clinical analysis of NSCLC patients reveals lack of association between EGFR mutation and TET1 downregulation

    Lung cancer is one of the leading causes of death from cancer worldwide, with a poor prognosis in advanced cases. In the past decade, epidermal growth factor receptor (EGFR) inhibitors have shown significant effi...

    J-I Lai, Y-C Lai, Y-C Chen, N-K Wang, J-N Pan, W-S Wang, S-C Chang in Cancer Gene Therapy (2017)

  7. Article

    Open Access

    AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B

    Biguanides such as metformin have previously been shown to antagonize hepatic glucagon-stimulated cyclic AMP (cAMP) signalling independently of AMP-activated protein kinase (AMPK) via direct inhibition of aden...

    M. Johanns, Y.-C. Lai, M.-F. Hsu, R. Jacobs, D. Vertommen in Nature Communications (2016)

  8. Article

    Open Access

    Macrophage migration inhibitory factor has a permissive role in concanavalin A-induced cell death of human hepatoma cells through autophagy

    Concanavalin A (ConA) is a lectin and T-cell mitogen that can activate immune responses. In recent times, ConA-induced cell death of hepatoma cells through autophagy has been reported and its therapeutic effec...

    Y-C Lai, Y-C Chuang, C-P Chang, T-M Yeh in Cell Death & Disease (2015)

  9. No Access

    Article

    Optimal track class assignment for a railroad network

    The track class and speed for North American railroads are governed by regulations from the Federal Railroad Administration. Better quality of track permits greater operational speeds and lower transportation ...

    Y-C Lai, M Dingler, S-Y Lin, K-C Liu in Journal of the Operational Research Society (2013)

  10. No Access

    Article

    Uncovering evolutionary ages of nodes in complex networks

    In a complex network, different groups of nodes may have existed for different amounts of time. To detect the evolutionary history of a network is of great importance. We present a spectral-analysis based met...

    G. -M. Zhu, H. J. Yang, R. Yang, J. Ren, B. Li in The European Physical Journal B (2012)

  11. No Access

    Article

    Impact of bloodstream infections on outcome and the influence of prophylactic oral antibiotic regimens in allogeneic hematopoietic SCT recipients

    This study aimed to determine the impact of blood stream infections (BSIs) on outcome of allogeneic hematopoietic SCT (HSCT), and to examine the influence of old (non-levofloxacin-containing) and new (levoflox...

    C-Y Liu, Y-C Lai, L-J Huang, Y-W Yang, T-L Chen, L-T Hsiao in Bone Marrow Transplantation (2011)

  12. No Access

    Article

    Information explosion on complex networks and control

    When a piece of information spreads on a complex network, error or distortion can occur. For a high error probability, the phenomenon of information explosion can occur where the number of distinct pieces of i...

    X. J. Ma, W.-X. Wang, Y.-C. Lai, Z. Zheng in The European Physical Journal B (2010)

  13. No Access

    Article

    Correlation between Klebsiella pneumoniae carrying pLVPK-derived loci and abscess formation

    Klebsiella pneumoniae-caused liver abscess (KLA) is an emerging infectious disease. However, factors other than K1-specific loci that contribute to the pathogenesis of this disease have not been identified. pLVPK...

    H.-L. Tang, M.-K. Chiang, W.-J. Liou in European Journal of Clinical Microbiology … (2010)

  14. No Access

    Article

    Application of integrated GIS and multimedia modeling on NPS pollution evaluation

    In Taiwan, nonpoint source (NPS) pollution is one of the major causes of the impairment of surface waters. I-Liao Creek, located in southern Taiwan, flows approximately 90 km and drains toward the Kao** Rive...

    C. E. Lin, C. M. Kao, Y. C. Lai, W. L. Shan in Environmental Monitoring and Assessment (2009)

  15. No Access

    Article

    Stochastic resonance and energy optimization in spatially extended dynamical systems

    We investigate a class of nonlinear wave equations subject to periodic forcing and noise, and address the issue of energy optimization. Numerically, we use a pseudo-spectral method to solve the nonlinear stoc...

    Y.-C. Lai, K. Park, L. Rajagopalan in The European Physical Journal B (2009)

  16. No Access

    Article

    Autocrine activation of PDGFRα promotes the progression of ovarian cancer

    Platelet-derived growth factor receptor (PDGFR)α expression was found in ovarian cancer cells and tumors by microarray hybridization. This led us to test whether ovarian cancers also produce ligands for this rece...

    D Matei, R E Emerson, Y-C Lai, L A Baldridge, J Rao, C Yiannoutsos, D D Donner in Oncogene (2006)

  17. No Access

    Chapter

    On the Influence of Resonant States on Ballistic Transport in Open Quantum Dots: Spectroscopy and Tunneling in the Presence of Multiple Conducting Channels

    A fundamental issue in quantum mechanics concerns the manner in which the discrete level spectrum of an isolated system is modified when it is coupled to some external, macroscopic measuring environment. From ...

    R. Akis, J. P. Bird, D. Vasileska, D. K. Ferry in Electron Transport in Quantum Dots (2003)

  18. Chapter

    Performance Analysis of Rate-Based Flow Control under a Variable Number of Sources

    Rate-based flow control plays an important role for efficient traffic management of ABR service in ATM networks. In this paper, a performance analysis of a rate-based flow control mechanism is presented. In ou...

    Y.-C. Lai, Y.-D. Lin in Broadband Communications (2000)