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  1. No Access

    Article

    Neuromuscular transmission inElectrophorus electricus (L.)

    Le système neuromusculaire dansElectrophorus electricus est étudié avec des électrodes intracellulaires. La transmission neuromusculaire est supprimée avec D-tubocurarine (5 · 10−7 p/v) ou avec un excès des ions ...

    W. C. de Mello, Y. C. Chang in Experientia (1966)

  2. No Access

    Article

    Phylogenetic relationships between the chlorophyll a/b binding protein (CAB) multigene family: An intra- and interspecies study

    The genome ofGlycine max (L.) Merr. cv. “Dare” contains a chlorophyll a/b binding (Cab) protein gene family consisting of 10 genes. The primary structures of two linkedCab genes (Cab 4 andCab 5) were determined. ...

    D. S. Demmin, E. J. Stockinger, Y. C. Chang… in Journal of Molecular Evolution (1989)

  3. No Access

    Article

    Effects of concanavalin A on desensitization kinetics of GABA responses inAchatina fulica neurons

    The effects of the lectin concanavalin A (Con A), on the kinetics of desensitization of the responses of voltage clampedAchatina fulica LP5 neuron to microperfused acetylcholine (ACh) and GABA were compared. Both...

    V. L. Arvanov, H. C. Chou, Y. H. Chen, R. C. Chen… in Cell Biology and Toxicology (1995)

  4. No Access

    Article

    Novel E2F decoy oligodeoxynucleotides inhibit in vitro vascular smooth muscle cell proliferation and in vivo neointimal hyperplasia

    The transcription factor, E2F, plays a critical role in the trans-activation of several genes involved in cell cycle regulation. Previous studies showed that the transfection of cis element double-stranded dec...

    J D Ahn, R Morishita, Y Kaneda, H S Kim, Y-C Chang, K-U Lee, J-Y Park… in Gene Therapy (2002)

  5. No Access

    Article

    Transcription factor decoy for AP-1 reduces mesangial cell proliferation and extracellular matrix production in vitro and in vivo

    Diabetic nephropathy is characterized by an expansion of glomerular mesangium, caused by mesangial cell proliferation and excessive accumulation of extracellular matrix (ECM) proteins, which eventually leads t...

    J D Ahn, R Morishita, Y Kaneda, H J Kim, Y D Kim, H J Lee, K U Lee… in Gene Therapy (2004)

  6. No Access

    Article

    Characterization of 4-O-methyl-ascochlorin-induced apoptosis in comparison with typical apoptotic inducers in human leukemia cell lines

    Apoptosis can be induced by various stimuli such as the ligands of death receptors, chemotherapeutic drugs and irradiation. It is generally believed that chemotherapeutic drugs induce mitochondrial damage, cyt...

    M. Tsuruga, H. Nakajima, S. Ozawa, M. Togashi, Y.-C. Chang, K. Ando, J. Magae in Apoptosis (2004)

  7. No Access

    Article

    Ring-Sp1 decoy oligonucleotide effectively suppresses extracellular matrix gene expression and fibrosis of rat kidney induced by unilateral ureteral obstruction

    Tubulointerstitial fibrosis is the consequence of an injury characterized by the accumulation of excess collagen and other extracellular matrix components, resulting in the destruction of the normal kidney arc...

    Y-M Chae, K-K Park, I-K Lee, J-K Kim, C-H Kim, Y-C Chang in Gene Therapy (2006)

  8. Article

    Contribution of guanine exchange factor H1 in phorbol ester-induced apoptosis

    Phorbol-12-myristate-13-acetate (PMA) treatment induces erythroblastoma D2 cells kept in suspension to undergo RhoA-dependent contraction and to become proapoptotic, while attached cells are induced to differe...

    Y-C Chang, H-H Lee, Y-J Chen, G M Bokoch, Z-F Chang in Cell Death & Differentiation (2006)

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  9. No Access

    Article

    p210Bcr−Abl desensitizes Cdc42 GTPase signaling for SDF-1α-directed migration in chronic myeloid leukemia cells

    Chronic myeloid leukemia (CML) is a lethal hematological disorder caused by the p210Bcr−Abl oncogene. Previous studies have suggested that p210Bcr−Abl transformation contributes to homing and retention defects, t...

    Y -C Chang, S -C Tien, H -F Tien, H Zhang, G M Bokoch, Z -F Chang in Oncogene (2009)

  10. No Access

    Article

    MMP-9 from sublethally irradiated tumor promotes Lewis lung carcinoma cell invasiveness and pulmonary metastasis

    Matrix metalloproteinases (MMPs) associate with tumor progression and metastasis. We sought to investigate the role of MMP-9 from sublethally irradiated tumor in accelerated pulmonary metastasis of Lewis lung ...

    C H Chou, C-M Teng, K-Y Tzen, Y-C Chang, J-H Chen, J C-H Cheng in Oncogene (2012)

  11. No Access

    Article

    Autocrine/paracrine mechanism of interleukin-17B receptor promotes breast tumorigenesis through NF-κB-mediated antiapoptotic pathway

    Gain of function of membrane receptor was a good strategy exploited by cancer cells to benefit own growth and survival. Overexpression of HER2 has been found to serve as a target for develo** trastuzumab to ...

    C-K Huang, C-Y Yang, Y-M Jeng, C-L Chen, H-H Wu, Y-C Chang, C Ma, W-H Kuo… in Oncogene (2014)

  12. Article

    Open Access

    Igf1 and Pacap rescue cerebellar granule neurons from apoptosis via a common transcriptional program

    A shift of the delicate balance between apoptosis and survival-inducing signals determines the fate of neurons during the development of the central nervous system and its homeostasis throughout adulthood. Bot...

    B Maino, V D’Agata, C Severini, MT Ciotti, P Calissano, A Copani… in Cell Death Discovery (2015)

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