160 Result(s)
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Article
Band offset determination of p-NiO/n-TiO2 heterojunctions for applications in high-performance UV photodetectors
Nickel oxide (NiO)-decorated titanium dioxide (TiO2) heterojunction photodetectors were prepared by two-step anodization. Surface scattering of NiO particles was successfully controlled by varying second-step ano...
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Open AccessInterplay of negative electronic compressibility and capacitance enhancement in lightly-doped metal oxide Bi0.95La0.05FeO3 by quantum capacitance model
Light-sensitive capacitance variation of Bi0.95La0.05FeO3 (BLFO) ceramics has been studied under violet to UV irradiation. The reversible capacitance enhancement up to 21% under 405 nm violet laser irradiation ha...
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Structural, chemical and electronic differences between bare and nitrogen-doped carbon nanoparticles
Comparisons between bare carbon (CPs) and nitrogen-doped carbon nanoparticles (N-CPs) synthesised using hydrothermal reaction are carried out. It was found that hydrothermal reaction of citric acid yields grap...
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Open AccessCXorf48 is a potential therapeutic target for achieving treatment-free remission in CML patients
Although the introduction of tyrosine kinase inhibitors (TKIs) has improved overall survival of patients with chronic myeloid leukemia (CML), about half of the patients eventually relapse after cessation of TK...
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One-port ring refractive index sensor with attached sub-ring
In this report, we propose a ring resonator with one port for surface normal input/output attached with another ring resonator. A resonance generated by one of the ring resonators is used for sensing and that ...
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Article
Turnover Frequency in Solar Microwave Bursts with an Extremely Flat Optically Thin Spectrum
Four microwave bursts have been selected from the Nobeyama Radio Polarimeter (NoRP) observations with an extremely flat spectrum in the optically thin part and a very hard spectral index between 0 and −1 in the m...
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Open AccessGenetic basis of myeloid transformation in familial platelet disorder/acute myeloid leukemia patients with haploinsufficient RUNX1 allele
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Deficiency in WT1-targeting microRNA-125a leads to myeloid malignancies and urogenital abnormalities
The Wilms’ tumor gene WT1 is overexpressed in leukemia and solid tumors and has an oncogenic role in leukemogenesis and tumorigenesis. However, precise regulatory mechanisms of WT1 overexpression remain undetermi...
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Open AccessRUNX1 haploinsufficiency results in granulocyte colony-stimulating factor hypersensitivity
RUNX1/AML1 is among the most commonly mutated genes in human leukemia. Haploinsufficiency of RUNX1 causes familial platelet disorder with predisposition to myeloid malignancies (FPD/MM). However, the molecular me...
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Impaired hematopoietic differentiation of RUNX1-mutated induced pluripotent stem cells derived from FPD/AML patients
Somatic mutation of RUNX1 is implicated in various hematological malignancies, including myelodysplastic syndrome and acute myeloid leukemia (AML), and previous studies using mouse models disclosed its critical r...
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Article
Recent Northern Hemisphere stratospheric HCl increase due to atmospheric circulation changes
Policies have been in place since 1987 to reduce the release of chlorine atoms in the stratosphere, where they deplete ozone; here observations show that since 2007 hydrogen chloride has been increasing in the...
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In vivo eradication of MLL/ENL leukemia cells by NK cells in the absence of adaptive immunity
It remains unclear how the immune system affects leukemia development. To clarify the significance of the presence of immune systems in leukemia development, we transferred MLL/ENL leukemia cells into immune-c...
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Observation of quadrupole helix chirality and its domain structure in DyFe3(BO3)4
Resonant X-ray diffraction (RXD) uses X-rays in the vicinity of a specific atomic absorption edge and is a powerful technique for studying symmetry breaking by motifs of various multipole moments, such as elec...
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Open AccessMaintenance of complete remission after allogeneic stem cell transplantation in leukemia patients treated with Wilms tumor 1 peptide vaccine
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Fabrication of Porous Aluminum with Directional Pores through Continuous Casting Technique
Lotus-type porous aluminum with slender directional pores is fabricated via a continuous casting technique in pressurized hydrogen or a mixed gas containing hydrogen and argon. The influence of solidification con...
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CD138-negative clonogenic cells are plasma cells but not B cells in some multiple myeloma patients
Clonogenic multiple myeloma (MM) cells reportedly lacked expression of plasma cell marker CD138. It was also shown that CD19+ clonotypic B cells can serve as MM progenitor cells in some patients. However, it is u...
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Long-term WT1 peptide vaccination for patients with acute myeloid leukemia with minimal residual disease
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Tensile deformation of anisotropic porous copper with directional pores
The tensile deformation of anisotropic porous copper with unidirectionally oriented cylindrical pores was investigated by an acoustic emission method. In the loadings parallel and perpendicular to the orientat...
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Fabrication of Porous Iron with Directional Pores through Thermal Decomposition of Chromium Nitride
Lotus-type porous iron with long directional pores was fabricated by a continuous zone melting technique through thermal decomposition of chromium nitride Cr1.18N. Nitrogen decomposed from the nitride powders dis...
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Article
Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation
Mixed-lineage-leukemia (MLL) fusion oncogenes are closely involved in infant acute leukemia, which is frequently accompanied by mutations or overexpression of FMS-like receptor tyrosine kinase 3 (FLT3). Earlier s...