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Article
Intracellular angiotensin-(1–12) changes the electrical properties of intact cardiac muscle
In the present work, the influence of intracellular injection of angiotensin-(1–12) [Ang-(1–12)] on the electrical properties of the intact left ventricle of Wistar Kyoto rats was investigated with electrophys...
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Article
Electrical activity of the heart and angiotensin-converting enzyme inhibitors on the hyperpolarising action of enalapril
This paper describes the effect of angiotensin- converting enzyme (ACE) inhibitors on the electrical properties of the heart, particularly the effect of these drugs on heart cell coupling and impulse propagati...
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Article
Cell-to-cell coupling assayed by means of electrical measurements
The importance of electrical measurements in the evaluation of cell-to-cell coupling in heart muscle was discussed. The presence of gap junctions in heart and smooth muscle, and the implications of this for el...
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Article
Effect of 2–4-dinitrophenol on intercellular communication in mammalian cardiac fibres
The effect of 2–4-dinitrophenol (DNP) on cell communication, in canine Purkinje fibres, was investigated. It was found that DNP (0.5 mM) suppressed the electrical coupling in about 10 min. This effect of DNP w...
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Article
Passive electrical properties of the atrio-ventricular node
The passive electrical properties of the atrioventricular node and of the atrial muscle of the rabbit heart were determined. To polarize the cells, a small suction electrode was used. The space constant of the...
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Article
Sodium pump: Its importance to intercellular communication in heart fibres
The effect of ouabain on the electrical coupling of canine Purkinje cells was investigated. It was found that the glycoside decreases cell communication through an increase in junctional resistance, what suppo...
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Article
Uncoupling of heart cells produced by intracellular sodium injection
L'influence de l'augmentation de la teneur en Na+ intracellulaire sur le processus de communication entre les cellules cardiaques du lapin est étudiée. Une suppression de la communication électrique est provoquée...
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Article
Influence of temperature on myocardial healing-over
L'influence de la température dans le phénoméne de suppression des potentiels de lésion «healingover» du muscle cardiaque deBufo marinus est édudiée avec des électrodes extracellulaires. A la température de 15°C ...
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Article
Neuromuscular transmission inElectrophorus electricus (L.)
Le système neuromusculaire dansElectrophorus electricus est étudié avec des électrodes intracellulaires. La transmission neuromusculaire est supprimée avec D-tubocurarine (5 · 10−7 p/v) ou avec un excès des ions ...
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Article
Hyperpolarizing Action Potentials recorded from the Œsophagus of Ascaris lumbricoides
THE œsophagus of Ascaris is a stout cylindrical organ up to 7 mm in length and more than 1 mm in diameter, which in fresh preparations is often seen to contract rhythmically. Vigorous contractions are also elicit...
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Article
Inhibitory action ofγ-aminobutyric acid (GABA) onAscaris muscle
Die somatische Muskulatur vonAscaris lumbricoides wird durchγ-Aminobuttersäure in Konzentrationen von 10−6-10−5 M völlig gehemmt. Eine hnliche Hemmung wird durch Piperazin (10−3 M) erzielt. Beide Substanzen steig...
