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Article
Open AccessFGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium
Breast cancer is one of the most common malignancies in women. Genome-wide association studies have identified FGFR2 as a breast cancer susceptibility gene. Common variation in other fibroblast growth factor (FGF...
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Article
Open AccessAnthropometric measures and epithelial ovarian cancer risk among Chinese women: results from the Shanghai Women’s Health Study
Studies of anthropometric measures and ovarian cancer risk have predominantly included women of European descent with mixed findings.
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Article
Body weight, fat distribution and colorectal cancer risk: a report from cohort studies of 134 255 Chinese men and women
The objective was to evaluate the association of body size and fat distribution with the risk of colorectal cancer (CRC) in Chinese men and women.
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Article
Genetic variants in vitamin D metabolism-related genes and body mass index: analysis of genome-wide scan data of approximately 7000 Chinese women
Vitamin D deficiency has been consistently associated with obesity. However, it is unclear whether vitamin D deficiency is the cause or consequence of obesity. We investigated this question by evaluating the a...
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Article
Open AccessBlood leukocyte Alu and LINE-1 methylation and gastric cancer risk in the Shanghai Women's Health Study
Recent data suggest a link between blood leukocyte DNA methylation, and cancer risk. However, reports on DNA methylation from a prospective study are unavailable for gastric cancer.
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Article
Open AccessPhysical activity and breast cancer risk in Chinese women
The influence of different types and intensities of physical activity on risk for breast cancer is unclear.
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Article
Open AccessMetabolic syndrome and insulin resistance in relation to biliary tract cancer and stone risks: a population-based study in Shanghai, China
Serum lipids, diabetes, and obesity, individual components of metabolic syndrome, are associated with biliary tract cancer and stone risk, but the associations of metabolic syndrome or insulin resistance with ...
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Article
Open AccessPlasma pepsinogens, antibodies against Helicobacter pylori, and risk of gastric cancer in the Shanghai Women's Health Study Cohort
Circulating pepsinogens can indicate atrophic gastritis, a precursor of gastric cancer. We tested the association between gastric cancer and plasma pepsinogens and antibodies against Helicobacter pylori in a case...
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Article
Open AccessDiabetes in relation to biliary tract cancer and stones: a population-based study in Shanghai, China
Biliary tract cancers are rare but fatal malignancies. Diabetes has been related to biliary stones, but its association with biliary tract cancers is less conclusive.
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Article
Open AccessReproductive factors and risks of biliary tract cancers and stones: a population-based study in Shanghai, China
Parity has been linked to gallbladder cancer and gallstones, but the effects of other reproductive factors are less clear.
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Article
Variants in circadian genes and prostate cancer risk: a population-based study in China
Circadian genes influence a variety of biological processes that are important in prostate tumorigenesis including metabolism. To determine if variants in circadian genes alter prostate cancer risk, we genotyp...
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Article
Open AccessBody size and the risk of biliary tract cancer: a population-based study in China
Though obesity is an established risk factor for gall bladder cancer, its role in cancers of the extrahepatic bile ducts and ampulla of Vater is less clear, as also is the role of abdominal obesity. In a popul...
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Article
Body mass index at various ages and mortality in Chinese women: impact of potential methodological biases
Inadequate control for potential methodological biases has been suggested as an explanation for the conflicting findings concerning the relationship between body mass index (BMI) and mortality.
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Article
Open AccessDuration of breast-feeding and the incidence of type 2 diabetes mellitus in the Shanghai Women’s Health Study
The aim of this study was to examine the association between lifetime breast-feeding and the incidence of type 2 diabetes mellitus in a large population-based cohort study of middle-aged women.
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Article
Impacts of weight change on prehypertension in middle-aged and elderly women
Individuals with prehypertension, a new blood pressure category defined as systolic blood pressure of 120–139 mm Hg and/or diastolic blood pressure of 80–89 mm Hg, are at an increased risk for heart diseases a...
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Article
Open AccessGallstones and the risk of biliary tract cancer: a population-based study in China
We conducted a population-based study of 627 patients with biliary tract cancers (368 of gallbladder, 191 bile duct, and 68 ampulla of Vater), 1037 with biliary stones, and 959 healthy controls randomly select...
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Article
CYP19A1 genetic polymorphisms may be associated with obesity-related phenotypes in Chinese women
To examine the relationship between genetic polymorphisms of the CYP19A1 gene and obesity-related phenotypes, body mass index (BMI) and waist-to-hip ratio (WHR).
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Article
Open AccessAnimal food intake and cooking methods in relation to endometrial cancer risk in Shanghai
We evaluated animal food intake and cooking methods in relation to endometrial cancer risk in a population-based case–control study in Shanghai, China. A validated food frequency questionnaire was used to coll...
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Article
Open AccessA case–control study in Shanghai of fruit and vegetable intake and endometrial cancer
In a population-based case–control study of 832 incident endometrial cancer cases and 846 frequency-matched controls among Chinese women in Shanghai, using a validated food-frequency questionnaire, dietary hab...
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Article
Risk of prostate cancer and family history of cancer: a population-based study in China
We evaluated prostate cancer risk and family history of cancers using data from a case–control study in China. Cancer information among first-degree relatives was collected from 709 subjects (238 cases and 471...