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Article
The effect of a geriatric evaluation on treatment decisions for older patients with colorectal cancer
Treating elderly colorectal cancer patients can be challenging. It is very important to carefully weigh the risks and benefits of potential treatments in individual patients. This treatment decision making can...
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Article
The impact of an ostomy on older colorectal cancer patients: a cross-sectional survey
Ostomies are being placed in 35 % of patients after colorectal cancer surgery. As decision-making regarding colorectal surgery is challenging in the older patients, it is important to have insight in the poten...
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Article
Open AccessA multi-centred randomised trial of radical surgery versus adjuvant chemoradiotherapy after local excision for early rectal cancer
Rectal cancer surgery is accompanied with high morbidity and poor long term functional outcome. Screening programs have shown a shift towards more early staged cancers. Patients with early rectal cancer can po...
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Article
Local administration of gentamicin collagen sponge in surgical excision of sacrococcygeal pilonidal sinus disease: a systematic review and meta-analysis of the literature
Surgical site infections occur in up to 24 % of patients after surgical excision of sacrococcygeal pilonidal sinus disease with primary wound closure. Local administration of antibiotics by a gentamicin colla...
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Article
Improved survival for older patients undergoing surgery for colorectal cancer between 2008 and 2011
Older colorectal cancer patients have a higher risk of postoperative complications, and the impact of adverse events on survival is also significantly higher. Innovations like laparoscopic surgery which improv...
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Article
Short-term follow-up after laparoscopic versus conventional total mesorectal excision for low rectal cancer in a large teaching hospital
Laparoscopic resection for low rectal cancer remains controversial, and large randomized studies on oncologic outcome are lacking. The objective of this study was to analyze the short-term results of laparosco...
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Article
Open AccessIntraoperative blood pressure changes as a risk factor for anastomotic leakage in colorectal surgery
Anastomotic leakage is a serious complication after colorectal surgery. Pre- and intraoperative factors may contribute to failure of colorectal anastomosis. In this study we have tried to determine risk factor...
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Article
Open AccessPhysical activity and breast cancer risk in Chinese women
The influence of different types and intensities of physical activity on risk for breast cancer is unclear.
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Article
Afgebroken K-draad tijdens schroefosteosynthese van collum femoris bij jonge patiënt
Mediale collumfracturen zijn veel geziene fracturen in de traumatologie. Zij hebben echter een lage incidentie bij jonge patiënten. Deze casus beschrijft het peroperatief afbreken van een kirschner (K)-draad b...
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Article
Validation of 70-gene prognosis signature in node-negative breast cancer
Purpose The 70-gene prognosis signature (van’t Veer et al., Nature 415(6871):530–536, 2002) may improve the selection of lymph node-negative breast cancer patients for adjuvant systemic therapy. Optimal validatio...
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Article
Fatigue of bituminous mixtures
This paper presents an interlaboratory test campaign organized by the RILEM 182-PEB Technical Committee. In the campaign, 11 different test methods, comprising uniaxial tension/compression, 2-, 3- and 4-point ...
