48 Result(s)

Article

Necrostatin-1 reverts shikonin-induced necroptosis to apoptosis

Degterev et al. previously demonstrated that death receptor mediated apoptosis could be diverted to necroptosis when apoptosis signaling was blocked, suggesting that necroptosis may function as a backup mechan...

Weidong Han, Jiansheng **e, Ling Li, Zhen Liu, Xun Hu in Apoptosis (2009)

Article

Polymorphisms of Thymidylate Synthase in the 5′- and 3′-Untranslated Regions and Gastric Cancer

Studies investigating the association of polymorphisms in the 5′-untranslated regions (5′UTR) and 3′-untranslated regions (3′UTR) of thymidylate synthase with gastric cancer susceptibility and sensitivity to f...

Wen Zhuang, **ao-Ting Wu, Yong Zhou, Guan-Jian Liu… in Digestive Diseases and Sciences (2009)

Article

The Effectiveness of the Treatment of Octreotide on Chylous Ascites After Liver Cirrhosis

Octreotide is a crucial drug used for treating patients with chylous ascites; however, there have been few reports related to octreotide that are being used in cirrhotic patients. Thus, this thesis is designe...

Dong Xun Zhou, Hua Bang Zhou, Qing Wang, Shan Shan Zou… in Digestive Diseases and Sciences (2009)

Article

Interleukin10 -592 Promoter Polymorphism Associated with Gastric Cancer Among Asians: A Meta-Analysis of Epidemiologic Studies

Studies investigating the association between interleukin10 (IL10) -592 promoter polymorphism and gastric cancer risk report conflicting results. The objective of this study was to quantitatively summarize the...

Wen Zhuang, **ao-Ting Wu, Yong Zhou, Liu Liu… in Digestive Diseases and Sciences (2010)

Article

Glutathione S-Transferase M1 Null Genotype Associated with Gastric Cancer Among Asians

The Glutathione S-transferases (GSTs) play multiple roles in the pathogenesis and treatment of cancer. Studies investigating the association between Glutathione S-transferase M1 (GSTM1) null genotype and gastr...

Hong Wang, Yong Zhou, Wen Zhuang, Yi-Qiong Yin… in Digestive Diseases and Sciences (2010)

Article

Granulocyte Colony-Stimulating Factor Enhances Bone Marrow Mononuclear Cell Homing to the Liver in a Mouse Model of Acute Hepatic Injury

Experiments have reported that granulocyte colony stimulating factor (G-CSF) can mobilize stem cells. However, few studies have examined the effect of G-CSF on bone marrow mononuclear cell (BMMC) mobilization,...

Shi-Zhu **, **ang-Wei Meng, Xun Sun, Ming-Zi Han… in Digestive Diseases and Sciences (2010)

Article

Effects of RNAi-Mediated Matrix Metalloproteinase-2 Gene Silencing on the Invasiveness and Adhesion of Esophageal Carcinoma Cells, KYSE150

Esophageal carcinoma is one of the main malignancies in China. Previous studies indicated that matrix metalloproteinases (MMPs) play important roles in the process of tumor invasion and metastasis in several t...

Yu-Guang Shen, Yi-Jun Xu, Zhen-Liang Shi, Hong-Li Han… in Digestive Diseases and Sciences (2012)

Article

Esophageal Squamous Cell Carcinoma: Assessing Tumor Angiogenesis Using Multi-Slice CT Perfusion Imaging

The purpose of this study was to investigate the correlation between multi-slice computed tomographic perfusion imaging (CTPI) parameters and immunohistologic markers of angiogenesis in esophageal squamous cel...

Tao Song, Yu-Guang Shen, Na-Na Jiao, **n-Hui Li… in Digestive Diseases and Sciences (2012)

Article

CD30 Ligand/CD30 Interaction Is Involved in Pathogenesis of Inflammatory Bowel Disease

Although CD30 has long been recognized as an important marker in many lymphomas of diverse origin, and as an activation molecule on B and T cells, its primary function has remained obscure. Soluble CD30 (sCD30...

Shinichi Somada, Hiromi Muta, Kazuhiko Nakamura, Xun Sun… in Digestive Diseases and Sciences (2012)

Article

Neoadjuvant Chemoradiotherapy Could Improve Survival Outcomes for Esophageal Carcinoma: A Meta-Analysis

The effectiveness of neoadjuvant chemoradiotherapy in patients with resectable esophageal carcinoma remains controversial.

Dong-Bin Wang, Xun Zhang, Hong-Li Han, Yi-Jun Xu… in Digestive Diseases and Sciences (2012)

Article

Effect of High-Dose Nano-selenium and Selenium–Yeast on Feed Digestibility, Rumen Fermentation, and Purine Derivatives in Sheep

The aim of this study was to evaluate the effect of nano-selenium (NS) and yeast–selenium (YS) supplementation on feed digestibility, rumen fermentation, and urinary purine derivatives in sheep. Six male rumin...

Wenjuan Xun, Liguang Shi, Wenbin Yue, Chunxiang Zhang… in Biological Trace Element Research (2012)

Article

Analysis of the Genome-Wide DNA Methylation Profile of Side Population Cells in Hepatocellular Carcinoma

DNA methylation plays an important role in maintaining pluripotency and regulating the differentiation of stem cells, but the DNA methylation profile of stem cells in hepatocellular carcinoma (HCC) remains unc...

**g-Ming Zhai, **ao-Yu Yin, Xun Hou, **ao-Yi Hao… in Digestive Diseases and Sciences (2013)

Article

Betaine Protects Against High-Fat-Diet-Induced Liver Injury by Inhibition of High-Mobility Group Box 1 and Toll-Like Receptor 4 Expression in Rats

Previous studies have shown that betaine prevents alcohol-induced liver injury and improves liver function. The purpose of this study was to investigate the hepatoprotective effects of betaine on nonalcoholic ...

Wei Zhang, Lu-wen Wang, Li-kun Wang, Xun Li, Hong Zhang… in Digestive Diseases and Sciences (2013)

Article

A Case of Primary Malignant Melanoma of the Esophagus

Luoluo Yang, Xun Sun, **angwei Meng in Digestive Diseases and Sciences (2013)

Article

Downregulation of TLR4 and 7 mRNA Expression Levels in Broiler’s Spleen Caused by Diets Supplemented with Nickel Chloride

Toll-like receptors (TLRs) are important immune receptors in discriminating self from nonself and in initiating the innate and adaptive immune response. TLR4 and TLR7 have been proven to be highly expressed in...

Jianying Huang, Hengmin Cui, ** Peng, **g Fang… in Biological Trace Element Research (2014)

Article

Effect of Dietary Nickel Chloride on Splenic Immune Function in Broilers

This study was designed to evaluate the effects of dietary nickel chloride (NiCl₂) on the splenic immunity in broilers by observing changes of cytokine mRNA expression and protein levels, immunoglobulin (IgA, IgG...

Jianying Huang, Hengmin Cui, ** Peng, **g Fang… in Biological Trace Element Research (2014)

Article

Effects of Nickel Chloride on the Erythrocytes and Erythrocyte Immune Adherence Function in Broilers

This study was conducted to investigate the immune adherence function of erythrocytes and erythrocyte induced by dietary nickel chloride (NiCl₂) in broilers fed on a control diet and three experimental diets supp...

Jian Li, Bangyuan Wu, Hengmin Cui, ** Peng, **g Fang… in Biological Trace Element Research (2014)

Article

NiCl₂-Down-Regulated Antioxidant Enzyme mRNA Expression Causes Oxidative Damage in the Broiler^’s Kidney

The kidney serves as a major organ of nickel (Ni) excretion and is a target organ for acute Ni toxicity due to Ni accumulation. There are no studies on the Ni or Ni compound-regulated antioxidant enzyme mRNA e...

Hongrui Guo, Bangyuan Wu, Hengmin Cui, ** Peng… in Biological Trace Element Research (2014)

Article

Inhibitive Effects of Nickel Chloride (NiCl₂) on Thymocytes

The purpose of this study was to define the inhibitive effects of dietary nickel chloride (NiCl₂) on thymocytes in broilers fed on diets supplemented with 0, 300, 600, and 900 mg/kg of NiCl₂ for 42 days. We exami...

Kun Tang, Hongrui Guo, Jie Deng, Hengmin Cui, ** Peng… in Biological Trace Element Research (2015)

Article

Hepatoprotective Effect of Ulinastatin in a Rat Model of Major Hepatectomy After Obstructive Jaundice

To date, major hepatectomy with obstructive jaundice is still a highly risky and difficult surgery because of the high rate of complications. An excessive inflammatory response may be the primary hindrance to ...

Xun Li, **g Li, Yang-Jie Ou, **ao-Xu Zhu, **ao-Yu Yin… in Digestive Diseases and Sciences (2015)