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Article
Open Accessmmu-miR-374b-5p modulated inflammatory factors via downregulation of C/EBP β/NF-κB signaling in Kupffer cells during Echinococcus multilocularis infection
Alveolar echinococcosis (AE) is an important infectious disease caused by the metacestode larvae of Echinococcus multilocularis, seriously threatening global public health security. Kupffer cells (KCs) play impor...
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Article
Open AccessTh17 cell differentiation induced by cytopathogenic biotype BVDV-2 in bovine PBLCs
Bovine viral diarrhea virus (BVDV) is a major pathogen that causes bovine viral diarrhea/mucosal disease (BVD-MD), which has become a global infectious disease due to its wide spread and the lack of effective ...
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Article
Open AccessThe genome of the thin-necked bladder worm Taenia hydatigena reveals evolutionary strategies for helminth survival
Taenia hydatigena is a widespread gastrointestinal helminth that causes significant health problems in livestock industry. This parasite can survive in a remarkably wide range of intermediate hosts and affects th...
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Article
Open AccessRegulation of DNA methylation on key parasitism genes of Cysticercus cellulosae revealed by integrative epigenomic-transcriptomic analyses
The life cycle of Taenia solium is characterized by different stages of development, requiring various kinds of hosts that can appropriately harbor the eggs (proglottids), the oncospheres, the larvae and the adul...
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Article
Open AccessPrimary characterization of the immune response in pigs infected with Trichinella spiralis
Trichinellosis, which is caused by Trichinella spiralis (T. spiralis), is a serious zoonosis. Pigs play an important role in the transmission of human trichinellosis. Characterizing the immune response to T. spir...
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Article
Open AccessImmunoproteomic analysis of the excretory-secretory products of Trichinella pseudospiralis adult worms and newborn larvae
The nematode Trichinella pseudospiralis is an intracellular parasite of mammalian skeletal muscle cells and exists in a non-encapsulated form. Previous studies demonstrated that T. pseudospiralis could induce a l...
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Article
Open AccessErratum: Comparative genomics reveals adaptive evolution of Asian tapeworm in switching to a new intermediate host
Nature Communications 7:: Article number: 12485 (2016); Published: 22 September 2016; Updated: 3 November 2016 This Article contains errors in Fig. 3. In panel b, the axes are displaced relative to the data, a...
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Article
Open AccessComparative genomics reveals adaptive evolution of Asian tapeworm in switching to a new intermediate host
Taenia saginata, Taenia solium and Taenia asiatica (beef, pork and Asian tapeworms, respectively) are parasitic flatworms of major public health and food safety importance. Among them, T. asiatica is a newly reco...
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Article
Open AccessAnalysis of codon usage pattern in Taenia saginata based on a transcriptome dataset
Codon usage bias is an important evolutionary feature in a genome and has been widely documented in many genomes. Analysis of codon usage bias has significance for mRNA translation, design of transgenes, new g...
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Article
Open AccessGenome-wide analysis of regulatory proteases sequences identified through bioinformatics data mining in Taenia solium
Cysticercosis remains a major neglected tropical disease of humanity in many regions, especially in sub-Saharan Africa, Central America and elsewhere. Owing to the emerging drug resistance and the inability of...
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Article
Open AccessMultiple microRNAs targeted to internal ribosome entry site against foot-and-mouth disease virus infection in vitro and in vivo
Foot-and-mouth disease virus (FMDV) causes a severe vesicular disease in domestic and wild cloven-hoofed animals. Because of the limited early protection induced by current vaccines, emergency antiviral strate...
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Article
Phylogenetic analysis of two Chinese orf virus isolates based on sequences of B2L and VIR genes
Orf virus (ORFV) is an enveloped virus with a double-stranded DNA genome, causing a contagious pustular dermatitis, mainly in goats and sheep. In this study, two strains of ORFV were isolated from sheep and go...
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Article
Open AccessThe genomes of four tapeworm species reveal adaptations to parasitism
Tapeworms (Cestoda) cause neglected diseases that can be fatal and are difficult to treat, owing to inefficient drugs. Here we present an analysis of tapeworm genome sequences using the human-infective species Ec...
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Article
A Combined Use of Autolysin p60 and Listeriolysin O Antigens Induces High Protective Immune Responses Against Listeria monocytogenes Infection
Listeria monocytogenes is an intracellular bacterium responsible for listeriosis in both humans and animals. Infected livestock is believed to be one source of this pathogen. Vaccination is an op...
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Article
Open AccessOutbreaks of highly pathogenic porcine reproductive and respiratory syndrome in Jiangxi province, China
In 2007, herds of pigs in Jiangxi Province, China experienced outbreaks of a severe form of suspected porcine reproductive and respiratory syndrome (PRRS) characterized by high fever, high morbidity and mortal...
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Article
Map** of Taenia solium TSOL18 antigenic epitopes by phage display library
Taenia solium is a cestode parasite that causes cysticercosis in humans and pigs. TSOL18 has been identified as a host-protective oncosphere antigen. To obtain mouse monoclonal antibodies (mAbs) against TSOL18 an...
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Article
Comparison of 18S ribosomal RNA gene sequences of Eurytrema coelmaticum and Eurytrema pancreaticum
The partial 18S rRNA sequences of E. coelmaticum and E. pancreaticum were amplified using conserved primers and an evolutionary tree was constructed using Neighbor-Joining. The percent identity of Eurytrema speci...
