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Article
Open Access“Qi Nan” agarwood restores podocyte autophagy in diabetic kidney disease by targeting EGFR signaling pathway
Diabetic kidney disease (DKD) is a microvascular complication of diabetes mellitus, contributing to end-stage renal disease with limited treatment options. The development of DKD is attributed to podocyte inju...
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Article
Open AccessTailored apoptotic vesicles promote bone regeneration by releasing the osteoinductive brake
Accumulating evidence has demonstrated that apoptotic vesicles (apoVs) derived from mesenchymal stem cells (MSCs; MSC-apoVs) are vital for bone regeneration, and possess superior capabilities compared to MSCs ...
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Article
Open AccessTooth brushing with fluoridated toothpaste and associated factors among Chinese adolescents: a nationwide cross-sectional study
Tooth brushing with fluoridated toothpaste has become the most important way to provide the anti-caries effect of fluoride around the world. China has promoted the use of fluoridated toothpaste since 1989. How...
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Article
Open AccessHeavy metals in drinking water and periodontitis: evidence from the national oral health survey from China
Periodontitis has become an increasingly important public health issue, coupled with a high economic burden for prevention and treatment. Exposure to essential trace heavy metals has been associated with vario...
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Article
Open AccessDecomposing socioeconomic inequalities in dental caries among Chinese adults: findings from the 4th national oral health survey
This cross-sectional study aimed to investigate socioeconomic inequalities in dental caries among adults (35 years and older) in China and explore the contributions of various factors to these inequalities.
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Article
Open AccessD-Mannose prevents bone loss under weightlessness
Astronauts undergo significant microgravity-induced bone loss during space missions, which has become one of the three major medical problems hindering human's long-term space flight. A risk-free and antiresor...
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Article
Open AccessMacrophage-derived apoptotic vesicles regulate fate commitment of mesenchymal stem cells via miR155
In tissue engineering, mesenchymal stem cells (MSCs) are common seed cells because of abundant sources, strong proliferation ability and immunomodulatory function. Numerous researches have demonstrated that MS...
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Article
Open AccessIncome-related inequality and decomposition of edentulism among aged people in China
The aim of this study was to assess the income-related inequality of edentulism among the aged in China and identify the contributing factors.
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Article
Open AccessRelated factors of periodontal health among Chinese middle school students, findings from a national cross-sectional survey
To investigate the related risk factors of periodontal health status among Chinese middle school students.
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Article
Open AccessAldo-keto reductase family 1 member C1 regulates the osteogenic differentiation of human ASCs by targeting the progesterone receptor
As a promising way to repair bone defect, bone tissue engineering has attracted a lot of attentions from researchers in recent years. Searching for new molecular target to modify the seed cells and enhance the...
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Article
Open AccessLAMA2 regulates the fate commitment of mesenchymal stem cells via hedgehog signaling
Bone defects are a common clinical condition that has gained an increasing amount of attention in recent years. Causes of bone defect include tumors, inflammation, and fractures. Bone tissue engineering is a n...
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Article
Open AccessUtilization of dental services and associated factors among preschool children in China
This study sought to evaluate dental utilization among 3-,4-, and 5-year-old children in China and to use Andersen’s behavioural model to explore influencing factors, thereby providing a reference for future p...
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Article
Open AccessLow concentration flufenamic acid enhances osteogenic differentiation of mesenchymal stem cells and suppresses bone loss by inhibition of the NF-κB signaling pathway
As the representative of fenamic acids, an important group of NSAIDs, flufenamic acid (FFA) has been used for anti-inflammation and analgesia in the clinic. Recently, researches have focused on the role of som...
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Article
Exploring the oral microflora of preschool children
The oral cavity is one of the most important and complicated habitats in our body and supports diverse microbial communities. In this study, we aimed to determine the bacterial diversity and composition of var...
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Open AccessMeeting the oral health needs of 12-year-olds in China: human resources for oral health
An appropriate level of human resources for oral health [HROH] is required to meet the oral health needs of population, and enable maximum improvement in health outcomes. The aim of this study was to estimate ...
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Article
Open AccessTongue Coating and the Salivary Microbial Communities Vary in Children with Halitosis
Halitosis is a common symptom mainly caused by microbial activities in the oral cavity. Here, we used 16S rRNA gene pyrosequencing and metagenomic sequencing to examine oral microbial compositions and their funct...
