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  1. No Access

    Article

    METTL3 preferentially enhances non-m6A translation of epigenetic factors and promotes tumourigenesis

    METTL3 encodes the predominant catalytic enzyme to promote m6A methylation in nucleus. Recently, accumulating evidence has shown the expression of METTL3 in cytoplasm, but its function is not fully understood. He...

    Xueju Wei, Yue Huo, **gnan Pi, Yufeng Gao, Shuan Rao, Manman He… in Nature Cell Biology (2022)

  2. No Access

    Article

    MiRNA-221-3p desensitizes pancreatic cancer cells to 5-fluorouracil by targeting RB1

    Pancreatic cancer is a highly lethal disease due to its rapid dissemination and resistance to conventional chemotherapy. MicroRNAs (miRNAs) are emerging as novel regulators of chemoresistance, which modulate t...

    Lijun Zhao, Dongling Zou, Xueju Wei, Lanlan Wang, Yuanyuan Zhang, Siqi Liu… in Tumor Biology (2016)

  3. Article

    Open Access

    MicroRNA-320a promotes 5-FU resistance in human pancreatic cancer cells

    The drug-resistance of pancreatic cancer cells results in poor therapeutic effect. To predict the therapeutic effect of the chemotherapy drugs to specific patients and to reverse the resistance of pancreatic c...

    Weibin Wang, Lijun Zhao, Xueju Wei, Lanlan Wang, Siqi Liu, Yu Yang… in Scientific Reports (2016)

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