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Article
Open AccessVenous resection increases risk of chyle leak after total pancreatectomy for pancreatic tumors
Existing research on chyle leak (CL) after pancreatic surgery is mostly focused on pancreaticoduodenectomy and lacks investigation on total pancreatectomy (TP). This study aimed to explore potential risk facto...
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Article
Influence of Microstructure on Corrosion Properties of Fe–V Alloy from Vanadium Slag
Four types of multiphase Fe–V alloys were examined, comprising ferrite, pearlite, and bainite microstructures. Electrochemical impedance spectroscopy and potentiodynamic polarization were employed to study the...
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Article
Lateral lymph node metastasis in papillary thyroid microcarcinoma: a study of 5241 follow-up patients
To investigate the impact of lateral lymph node metastasis in papillary thyroid microcarcinoma (PTMC).
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Article
Open AccessDevelopment and validation of a nomogram model based on pretreatment ultrasound and contrast-enhanced ultrasound to predict the efficacy of neoadjuvant chemotherapy in patients with borderline resectable or locally advanced pancreatic cancer
To develop a nomogram using pretreatment ultrasound (US) and contrast-enhanced ultrasound (CEUS) to predict the clinical response of neoadjuvant chemotherapy (NAC) in patients with borderline resectable pancre...
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Article
MBD1 protects replication fork stability by recruiting PARP1 and controlling transcription-replication conflicts
The replication-stress response is essential to ensure the faithful transmission of genetic information to daughter cells. Although several stress-resolution pathways have been identified to deal with replicat...
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Article
Open AccessExploring microproteins from various model organisms using the mip-mining database
Microproteins, prevalent across all kingdoms of life, play a crucial role in cell physiology and human health. Although global gene transcription is widely explored and abundantly available, our understanding ...
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Article
Open AccessPancreatic cancer stemness: dynamic status in malignant progression
Pancreatic cancer (PC) is one of the most aggressive malignancies worldwide. Increasing evidence suggests that the capacity for self-renewal, proliferation, and differentiation of pancreatic cancer stem cells ...
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Article
Analysis of free vibration characteristics of porous rectangular plates with variable thickness
Porous solid structures have attracted much attention because they are widely used in national defense, military industry, machinery, civil engineering and other fields. In this paper, the problem of free vibr...
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Article
Open AccessEGR1 induces EMT in pancreatic cancer via a P300/SNAI2 pathway
The prognosis of pancreatic cancer patients remains relatively poor. Although some patients would receive surgical resection, distant metastasis frequently occurs within one year. Epithelial-mesenchymal transi...
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Article
Open AccessSTOML2 restricts mitophagy and increases chemosensitivity in pancreatic cancer through stabilizing PARL-induced PINK1 degradation
Pancreatic cancer remains one of the most lethal diseases with a relatively low 5-year survival rate, and gemcitabine-based chemoresistance occurs constantly. Mitochondria, as the power factory in cancer cells...
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Article
Utilization of Vanadium Slag and Iron-Rich Red Mud for the Fabrication of Fe–V Alloy: Mechanism and Performance Analysis
An innovative technique that provides a new way to use vanadium slag and red mud has been developed. In the proposed method, vanadium slag was used to prepare Fe–V alloys by combining the slag with iron-rich r...
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Article
Smartphone touch gesture for right-handed older adults: touch performance and offset models
Older adults have difficulties with smartphone touch gestures, such as tap**, dragging, zooming, and rotating. To alleviate these difficulties, this study examined error patterns in interaction traces of old...
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Article
Open AccessKAT8 acetylation-controlled lipolysis affects the invasive and migratory potential of colorectal cancer cells
Epigenetic mechanisms involved in gene expression play an essential role in various cellular processes, including lipid metabolism. Lysine acetyltransferase 8 (KAT8), a histone acetyltransferase, has been repo...
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Chapter and Conference Paper
An Improved Multi-Instance Learning Model for Postoperative Early Recurrence Prediction of Hepatocellular Carcinoma Using Histopathological Images
HCC(Hepatocellular carcinoma) is one of the primary liver cancer around the world, and it produces a high mortality rate in clinical. Surgical resection is the first-line treatment choice for patients with HCC...
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Chapter and Conference Paper
A Transformer-Based Model for Preoperative Early Recurrence Prediction of Hepatocellular Carcinoma with Muti-modality MRI
Hepatocellular carcinoma (HCC) is the most common primary liver cancer which accounts for a high mortality rate in clinical, and the most effective treatment for HCC is surgical resection. However, patients wi...
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Article
Spatial-temporal Characteristics of Holocene Paleosols in the Chinese Loess Plateau and Paleoclimatic Significance
The evolution of Holocene climate was investigated using grain size and magnetic susceptibility of the Holocene paleosols from Baicaoyuan (BCY), **feng (XF) and Linyou (LY) sections in the northwest, central a...
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Article
Open AccessMultidrug resistance genes screening of pancreatic ductal adenocarcinoma based on sensitivity profile to chemotherapeutic drugs
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancer types and chemotherapeutic drug resistance is a stumbling block in improving the overall survival of PDAC patients. The nature of specif...
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Article
Open AccessCHRNB2 represses pancreatic cancer migration and invasion via inhibiting β-catenin pathway
Pancreatic cancer is one of the most lethal disease with highly fatal and aggressive properties. Lymph node ratio (LNR), the ratio of the number of metastatic lymph nodes to the total number of examined lymph ...
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Article
Open AccessAuthor Correction: Artificial intelligence defines protein-based classification of thyroid nodules
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Article
Open AccessArtificial intelligence defines protein-based classification of thyroid nodules
Determination of malignancy in thyroid nodules remains a major diagnostic challenge. Here we report the feasibility and clinical utility of develo** an AI-defined protein-based biomarker panel for diagnostic...
