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Article
Population-based case–control study on DAPK1, RAR-β2 and MGMT methylation in liquid-based cytology
Methylated genes have the potential to provide a new generation of cancer biomarkers. The aim of this study was to investigate: (1) the promoter methylation status of DAPK1, RAR-β2 and MGMT in randomly selecte...
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Article
Identification of Acetylcholinesterase Inhibitors from Seeds of Plants of Genus Peganum by Thin-Layer Chromatography-Bioautography
In traditional Chinese medicine, plants of the genus Peganum have been used to treat cough, hypertension, diabetes, asthma, jaundice, lumbago, and many other ailments. In this study, seeds of the plants of genus
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Article
Acetylcholinesterase inhibitive activity-guided isolation of two new alkaloids from seeds of Peganum nigellastrum Bunge by an in vitro TLC- bioautographic assay
Acetylcholinesterase inhibitors (AChEIs) currently form the basis of the newest drugs available for the treatment of Alzheimer’s disease. For the aim of screening effective AChEIs, the methanol extracts of the...
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Article
Simultaneous Determination of Danshensu and Puerarin in Rat Plasma by LC-MS-MS and Its Application to a Pharmacokinetics and Bioequivalence Study after Oral Administration of Tongmai Drip** Pill and Tongmai Oral Solutions
The active components danshensu (DS) and puerarin (PA) of Tongmai drip** pills (TDP) and oral solution (TOS) were detected in rat plasma after liquid–liquid extraction and oral administration of formulated ...
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Article
Pharmacokinetic behavior of gentiopicroside from decoction of radix gentianae, gentiana macrophylla after oral administration in rats: A pharmacokinetic comaprison with gentiopicroside after oral and intravenous administration alone
The pharmacokinetics in rats of gentiopicroside (GPS) from orally administered decoctions ofRadix Gentianae (DRG) andGentiana macrophlla (DGM) were compared with that of GPS alone administered at 150 mg/kg orally...
