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Article
Open AccessThe emerging and diverse roles of F-box proteins in spermatogenesis and male infertility
F-box proteins play essential roles in various cellular processes of spermatogenesis by means of ubiquitylation and subsequent target protein degradation. They are the substrate-recognition subunits of SKP1–cu...
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Article
Open AccessElectroacupuncture as an effective therapy for Tapia’s syndrome after transoral intubation for general anesthesia: a case report and review of the literature
Tapia’s syndrome is a rare complication of airway manipulation under general anesthesia. Injuries to the vagus nerve (X) and hypoglossal nerve (XII) during transoral intubation are the primary cause of the dis...
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Article
Correction to: Evolution of chaperome gene expression and regulatory elements in the antarctic notothenioid fishes
A Correction to this paper has been published: https://doi.org/10.1038/s41437-020-00399-1
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Article
Evolution of chaperome gene expression and regulatory elements in the antarctic notothenioid fishes
Confined within the cold-stable Southern Ocean, Antarctic notothenioid fishes have undergone an evolutionary loss of the inducible heat shock response (HSR), while facing perpetual low-temperature challenges t...
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Molecular Origins and Mechanisms of Fish Antifreeze Evolution
Independent evolution of distinctive types of antifreeze glycoprotein (AFGP) and peptides (AFP) in various polar and subpolar bony fish lineages bespeaks the breath of evolutionary ingenuity in converging on a...
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Article
Association between KITLG Gene Polymorphisms and Testicular Germ Cell Tumors: A Systematic Review and Meta-analysis
It has been reported that c-KIT ligand (KITLG) gene polymorphisms may be associated with testicular germ cell tumors (TGCT). Owing to mixed and inconclusive results, we conducted a systematic review and meta-a...
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Article
Open AccessUsing Positively Charged Magnetic Nanoparticles to Capture Bacteria at Ultralow Concentration
Detecting bacteria at low concentrations without time-consuming culture processes would allow rapid diagnoses. Since electrostatic attraction exists between negatively charged bacterial cells and positively ch...
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Article
Open AccessEffective capture of circulating tumor cells from an S180-bearing mouse model using electrically charged magnetic nanoparticles
Technology enabling the separation of rare circulating tumor cells (CTCs) provides the potential to enhance our knowledge of cancer metastasis and improve the care of cancer patients. Modern detection approach...
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Article
Open AccessZCCHC13-mediated induction of human liver cancer is associated with the modulation of DNA methylation and the AKT/ERK signaling pathway
Previous studies have shown that zinc-finger CCHC-type containing 13 (ZCCHC13) is located in an imprinted gene cluster in the X-inactivation centre, but few published studies have provided evidence of its expr...
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Article
Open AccessNovel biomarker ZCCHC13 revealed by integrating DNA methylation and mRNA expression data in non-obstructive azoospermia
The objective of this study was to identify genes regulated by methylation that were involved in spermatogenesis failure in non-obstructive azoospermia (NOA). Testis biopsies of patients with NOA and OA (with ...
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Article
Open AccessIntegrated miRNA and mRNA expression profiling to identify mRNA targets of dysregulated miRNAs in non-obstructive azoospermia
The aim of this study was to identify mRNA targets of dysregulated miRNAs through the integrated analysis of miRNA and mRNA expression profiling in men with normal versus impaired spermatogenesis. The expressi...
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Article
Open AccessProtein genes in repetitive sequence—antifreeze glycoproteins in Atlantic cod genome
Highly repetitive sequences are the bane of genome sequence assembly, and the short read lengths produced by current next generation sequencing technologies further exacerbates this obstacle. An adopted practi...
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Article
Molecular phylogenetic relationships of China Seas groupers based on cytochrome b gene fragment sequences
The classification and evolutionary relationships are important issues in the study of the groupers. Cytochrome b gene fragment of twenty-eight grouper species within six genera of subfamily Epinephelinae was amp...
