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Biological evaluation of Korean medicinal plants(III)
The extracts of sixty Korean plants were evaluated for their biological activities such as antitumor activities against Sarcoma 180, Leukemia SN-36 and Ehrlich ascites carcinoma, antimicrobial activities and b...
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Article
Central nervous depressant activity of piperine
Piperine showed a central nervous system depressant activity which was characterized by the antagonistic effect against chemoshock seizure as well as potent muscular incoordination in mice.
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Article
AtObgC, a plant ortholog of bacterial Obg, is a chloroplast-targeting GTPase essential for early embryogenesis
Obg is a ribosome-associated GTPase essential for bacterial viability and is conserved in most organisms, from bacteria to eukaryotes. Obg is also expressed in plants, which predicts an important role for this...
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Article
OsPRA1 plays a significant role in targeting of OsRab7 into the tonoplast via the prevacuolar compartment during vacuolar trafficking in plant cells
In yeast and mammals, the Yip/PRA1 family of proteins has been reported to facilitate the delivery of Rab GTPases to the membrane by dissociating the Rab–GDI complex during vesicle trafficking. Recently, we id...
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Article
Clinical features of supervoiders who suffer from lower urinary tract symptoms: a propensity score-matching study
To evaluate the clinical characteristics of patients with maximal urine flow rate (Q max) ≥ 25 ml/s complaining of lower urinary tract symptoms (LUTS), using propensity score-matching analysis t...
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Article
Combined application of 2D correlated spectroscopy and 2D nuclear Overhauser enhancement spectroscopy to the brain metabolites
The 2D NMR has great potential for routine use in organic chemistry, biochemistry and structural biology. The 2D correlated spectroscopy (COSY) and 2D nuclear Overhauser enhancement (NOE) spectroscopy are part...
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Article
Open AccessStructural importance of the C-terminal region in pig aldo-keto reductase family 1 member C1 and their effects on enzymatic activity
Pig aldo-keto reductase family 1 member C1 (AKR1C1) belongs to AKR superfamily which catalyzes the NAD(P)H-dependent reduction of various substrates including steroid hormones. Previously we have reported two ...
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Article
Antioxidant activities and quality characteristics of omija (Schizandra chinesis Baillon) cookies
Omija fruit was included in cookie formulations and antioxidant properties and quality characteristics of omija cookies were determined. Five different cookie types were prepared using 0, 1.5, 3....
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Article
Open AccessComparison of carnivore, omnivore, and herbivore mammalian genomes with a new leopard assembly
There are three main dietary groups in mammals: carnivores, omnivores, and herbivores. Currently, there is limited comparative genomics insight into the evolution of dietary specializations in mammals. Due to ...
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Article
Effect of the ingredients on the microbial qualities of six varieties of Dasik during storage
This study was conducted to evaluate the microbial quality of 6 varieties of brown rice Dasik prepared with roasted bean powder, Omija juice, red ginseng, propolis, and a combination of red ginseng and propolis d...
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Article
Bioactive secondary metabolites produced by an endophytic fungus Gaeumannomyces sp. JS0464 from a maritime halophyte Phragmites communis
Endophytes, important plant-associated mycobionts, have attracted a great deal of attention because of their bioactive secondary metabolites. Even though halophytes have been reported to overcome salt stress v...
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Article
Clinical outcomes of everolimus in patients with advanced, nonfunctioning pancreatic neuroendocrine tumors: a multicenter study in Korea
Everolimus is a standard treatment option for advanced pancreatic neuroendocrine tumors (pNETs). This multicenter study evaluated the efficacy and safety of everolimus in low and intermediate grade advanced pN...
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Article
Recurrent esophageal perforation after anterior cervical spine surgery: case report
Delayed esophageal perforation after anterior cervical discectomy and fusion (ACDF) is an extremely rare cause of infection such as spondylodiscitis. We present a rare case in which a patient had two delayed e...
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Endoscopic Management of Renal Stone: Retrograde, Antegrade, and Combined Approaches
Owing to its technical development, tailored management for renal stones has become available to reduce mortality rates and increase surgical outcomes. In the era of flexible ureteroscopic surgery and miniatur...
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Article
The association between hepatitis and osteoporosis: a nested case-control study using a national sample cohort
The prevalence of hepatitis B was higher in osteoporosis patients than the control group, especially in females. However, the prevalence of hepatitis C was not different. The matching for various factors impro...
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Open AccessSolving the controversy of healthier organic fruit: Leaf wounding triggers distant gene expression response of polyphenol biosynthesis in strawberry fruit (Fragaria x ananassa)
The claim that organic agriculture produces higher levels of phytochemicals has been controversial for decades. Using strawberries as a model crop in field conditions, a preharvest leaf wounding stress was app...
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Rheumatoid arthritis and neurodegenerative dementia: a nested case-control study and a follow-up study using a national sample cohort
The present study evaluated the associations between rheumatoid arthritis (RA) and neurodegenerative dementia using a Korean national sample cohort.
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Open AccessAlpha-tocopherol exerts protective function against the mucotoxicity of particulate matter in amphibian and human goblet cells
Exposure to particulate matter (PM) in ambient air is known to increase the risk of cardiovascular disorders and mortality. The cytotoxicity of PM is mainly due to the abnormal increase of reactive oxygen spec...
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Rapid generation of transgenic and gene-edited Solanum nigrum plants using Agrobacterium-mediated transformation
In this study, genetic engineering methods, ranging from gene transformation to gene editing, were efficiently conducted on cotyledon explants in Solanum nigrum. Organogenic calli were observed on the explants fo...
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Correlation between prostatic urethral angulation and symptomatic improvement after surgery in patients with lower urinary tract symptoms according to prostate size
To investigate the effect of prostate anatomical factors on the changes in lower urinary tract symptoms (LUTS) and uroflowmetric values after surgery.