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  1. No Access

    Article

    Clinical targeting of HIV capsid protein with a long-acting small molecule

    Oral antiretroviral agents provide life-saving treatments for millions of people living with HIV, and can prevent new infections via pre-exposure prophylaxis1–5. However, some people living with HIV who are heavi...

    John O. Link, Martin S. Rhee, Winston C. Tse, Jim Zheng, John R. Somoza… in Nature (2020)

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    Article

    A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model

    People living with HIV (PLWH) have expressed concern about the life-long burden and stigma associated with taking pills daily and can experience medication fatigue that might lead to suboptimal treatment adher...

    Stephen R. Yant, Andrew Mulato, Derek Hansen, Winston C. Tse… in Nature Medicine (2019)