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  1. Article

    Open Access

    Quantitative proteomic screening uncovers candidate diagnostic and monitoring serum biomarkers of ankylosing spondylitis

    We sought to discover serum biomarkers of ankylosing spondylitis (AS) for diagnosis and monitoring disease activity.

    Mark Hwang, Shervin Assassi, Jim Zheng, Jessica Castillo… in Arthritis Research & Therapy (2023)

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  2. Article

    Open Access

    Long-acting capsid inhibitor protects macaques from repeat SHIV challenges

    Because no currently available vaccine can prevent HIV infection, pre-exposure prophylaxis (PrEP) with antiretrovirals (ARVs) is an important tool for combating the HIV pandemic1,2. Long-acting ARVs promise to bu...

    Samuel J. Vidal, Elena Bekerman, Derek Hansen, Bing Lu, Kelly Wang, Judy Mwangi… in Nature (2022)

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  3. No Access

    Article

    Clinical targeting of HIV capsid protein with a long-acting small molecule

    Oral antiretroviral agents provide life-saving treatments for millions of people living with HIV, and can prevent new infections via pre-exposure prophylaxis1–5. However, some people living with HIV who are heavi...

    John O. Link, Martin S. Rhee, Winston C. Tse, Jim Zheng, John R. Somoza… in Nature (2020)

  4. No Access

    Article

    A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model

    People living with HIV (PLWH) have expressed concern about the life-long burden and stigma associated with taking pills daily and can experience medication fatigue that might lead to suboptimal treatment adher...

    Stephen R. Yant, Andrew Mulato, Derek Hansen, Winston C. Tse… in Nature Medicine (2019)