-
Article
Open AccessEffects of genetically proxied lipid-lowering drugs on acute myocardial infarction: a drug-target mendelian randomization study
High low-density-lipoprotein (LDL) cholesterol has been associated with an increased risk of coronary artery diseases (CAD) including acute myocardial infarction (AMI). However, whether lipids lowering drug tr...
-
Article
Open AccessElevated blood remnant cholesterol and triglycerides are causally related to the risks of cardiometabolic multimorbidity
The connection between triglyceride-rich lipoproteins and cardiometabolic multimorbidity, characterized by the concurrence of at least two of type 2 diabetes, ischemic heart disease, and stroke, has not been d...
-
Article
Associations of healthy aging index and all-cause and cause-specific mortality: a prospective cohort study of UK Biobank participants
The healthy aging index (HAI) has been recently developed as a surrogate measure of biological age. However, to what extent the HAI is associated with all-cause and cause-specific mortality and whether this as...
-
Article
Qualitative identification of lonicerae japonicae flos in traditional chinese medicine using metabarcoding combined with specific mini-barcodes
Lonicerae japonicae flos, also known as **yinhua (JYH), is an important component of traditional Chinese patent medicine (TCPM) products. However, the potential for adulteration and substitution with low-qual...
-
Article
Total and regional fat-to-muscle mass ratio and risk of incident breast and ovarian cancers
The fat-to-muscle mass ratio (FMR) has been proposed as a meaningful indicator of risk of obesity. This study investigated the associations between total and regional FMR and incident breast/ovarian cancer.
-
Article
Open AccessPublisher Correction: Particle fusion of super-resolution data reveals the unit structure of Nup96 in Nuclear Pore Complex
-
Article
Open AccessParticle fusion of super-resolution data reveals the unit structure of Nup96 in Nuclear Pore Complex
Single molecule localization microscopy offers resolution nearly down to the molecular level with specific molecular labelling, and is thereby a promising tool for structural biology. In practice, however, the...
-
Article
Photoexcited cryptochromes interact with ADA2b and SMC5 to promote the repair of DNA double-strand breaks in Arabidopsis
Cryptochromes (CRYs) act as blue-light photoreceptors that regulate development and circadian rhythms in plants and animals and as navigating magnetoreceptors in migratory birds. DNA double-strand breaks (DSBs...
-
Article
Physicochemical, sensory characterisation and volatile components of 16 NFC pear juice
Pear (Pyrus spp.) has the function of clearing heat, reducing fire and moistening the lungs. Not from concentrated (NFC) pear juice can better maintain the nutrition, aroma and taste of pear fruit, which is worth...
-
Article
Open AccessUnmet supportive care needs of breast cancer survivors: a systematic sco** review
Breast cancer is the most common type of cancer in women worldwide. Though improved treatments and prolonged overall survival, breast cancer survivors (BCSs) persistently suffer from various unmet supportive c...
-
Article
Associations of polysocial risk score, lifestyle and genetic factors with incident type 2 diabetes: a prospective cohort study
We aimed to investigate the association between polysocial risk score (PsRS), an estimator of individual-level exposure to cumulative social risks, and incident type 2 diabetes in the UK Biobank study.
-
Article
Open AccessPublisher Correction: Size-fractionated microbiome observed during an eight-month long sampling in Jiaozhou Bay and the Yellow Sea
-
Article
Open AccessSize-fractionated microbiome observed during an eight-month long sampling in Jiaozhou Bay and the Yellow Sea
Jiaozhou Bay is a typical semi-enclosed bay with a temperate climate imposed by strong anthropogenic influence. To investigate microbial biodiversity and ecosystem services in this highly dynamic coastal envir...
-
Article
GWAS-associated bacteria and their metabolites appear to be causally related to the development of inflammatory bowel disease
Accumulating evidence has suggested that the imbalance of gut microbiota is commonly observed in patients with inflammatory bowel disease (IBD). However, it remains unclear whether dysbiosis is a cause or cons...
-
Article
Open AccessAuthor Correction: 53BP1 regulates heterochromatin through liquid phase separation
-
Article
Open Access53BP1 regulates heterochromatin through liquid phase separation
Human 53BP1 is primarily known as a key player in regulating DNA double strand break (DSB) repair choice; however, its involvement in other biological process is less well understood. Here, we report a previou...
-
Article
Open AccessBiological composition analysis of a natural medicine, Faeces Vespertilionis, with complex sources using DNA metabarcoding
Faeces Vespertilionis is a commonly used fecal traditional Chinese medicine. Traditionally, it is identified relying only on morphological characters. This poses a serious challenge to the composition analysis...
-
Article
Open AccessAssociation of healthy lifestyle including a healthy sleep pattern with incident type 2 diabetes mellitus among individuals with hypertension
Evidence is limited regarding the association of healthy lifestyle including sleep pattern with the risk of complicated type 2 diabetes mellitus (T2DM) among patients with hypertension. We aimed to investigate...
-
Article
Infrared Pedestrian Detection Method Based on Attention Model
A new infrared pedestrian detection method based on semantic segmentation is proposed. First, an attention model is introduced using traditional semantics to enhance the attention area of the pedestrian target...
-
Article
Design and characterization of bio-amine responsive films enriched with colored potato (Black King Kong) anthocyanin for visual detecting pork freshness in cold storage
Intelligent films serving as a response to a particular stimulus (e.g., biogenic amines) endow great potential to monitor the meat freshness. The aim of this study was to develop intelligent films with excelle...
