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  1. Article

    Open Access

    Targeting the E2F1/Rb/HDAC1 axis with the small molecule HR488B effectively inhibits colorectal cancer growth

    Colorectal cancer (CRC), the third most common cancer worldwide, remains highly lethal as the disease only becomes symptomatic at an advanced stage. Growing evidence suggests that histone deacetylases (HDACs),...

    Namin Duan, **aohui Hu, Huiran Qiu, Rui Zhou, Yuru Li, Wenxia Lu in Cell Death & Disease (2023)

  2. Article

    Open Access

    Notch Signaling Coordinates Progenitor Cell-Mediated Biliary Regeneration Following Partial Hepatectomy

    Aberrant transcriptional regulation contributes to the pathogenesis of both congenital and adult forms of liver disease. Although the transcription factor RBPJ is essential for liver morphogenesis and biliary ...

    Jie Lu, Yingqun Zhou, Tianyuan Hu, Hui Zhang, Miao Shen, ** Cheng in Scientific Reports (2016)

  3. No Access

    Chapter and Conference Paper

    Attribute Reduction of the Real Value Decision System Based on Conditional Entropy

    Research knowledge acquisition in the real valued decision system is the main directions of the granular computing. Based on the neighborhood of rough set theory and according to the characteristics of the re...

    Wenxia Lu, Qiaoyan Li in Foundations of Intelligent Systems (2014)