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Article

Targeting the E2F1/Rb/HDAC1 axis with the small molecule HR488B effectively inhibits colorectal cancer growth

Colorectal cancer (CRC), the third most common cancer worldwide, remains highly lethal as the disease only becomes symptomatic at an advanced stage. Growing evidence suggests that histone deacetylases (HDACs),...

Namin Duan, **aohui Hu, Huiran Qiu, Rui Zhou, Yuru Li, Wenxia Lu… in Cell Death & Disease (2023)