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Article
Intriguing Roles of Hippocampus-Synthesized 17β-Estradiol in the Modulation of Hippocampal Synaptic Plasticity
Accumulated studies have shown that 17β-estradiol (E2) can be de novo synthesized in the hippocampus, and its role in the regulation of hippocampal synaptic plasticity, which is the basis of learning and memor...
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Article
Open AccessRegulatory effects of the JAK3/STAT1 pathway on the release of secreted phospholipase A2-IIA in microvascular endothelial cells of the injured brain
Secreted phospholipase A2-IIA (sPLA2-IIA) is an inducible enzyme released under several inflammatory conditions. It has been shown that sPLA2-IIA is released from rat brain astrocytes after inflammatory stimulus,...
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Article
Screening Genes Related to Development and Injury of the Mouse Optic Nerve by cDNA Microarrays
The aim of this study was to screen genes related to the development and injury of the mouse optic nerve so as to provide possible target genes for gene-engineering therapy of central nervous system (CNS) inju...
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Article
Regulation of BMP4 on the proliferation and differentiation in SVZa neural stem cells
The neural stem cells in the anterior subventricular zone (SVZa) mainly generate the progenitors that will differentiate into neurons, and along a highly circumscribed migratory access — Rostral migratory stre...
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Article
Programmed cell death in develo** human fetal CNS
The spatial and temporal distributions of programmed cell death (PCD) in develo** central nervous system (CNS) of human fetuses ranging from 12 to 39 weeks of gestation were investigated using techniques of ...
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Article
Effect of the control proliferation of astrocyte on the formation of glial scars by antisenseGFAP retrovirus
Astrocytes play an important role in the formation of glial scars. In order to investigate the effect of inhibitingGFAP gene expression on normal, reactive astrocytes and on glial scar formation, the efficiency o...
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Article
Developmental study on the immunocytochemical localization of NOV protein-containing neurons in the rat brain
The localization and development of nephroblastoma overexpressed gene (nov) protein-immunoreactive neurons in the brain of E8-P300 rats have been studied using immunocytochemistry and image analysis. Results are ...
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Article
Somatostatin involved in transmission of nociceptive information induced by substance P in the spinal cord