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Article
CGI1746 targets σ1R to modulate ferroptosis through mitochondria-associated membranes
Ferroptosis is iron-dependent oxidative cell death. Labile iron and polyunsaturated fatty acid (PUFA)-containing lipids are two critical factors for ferroptosis execution. Many processes regulating iron homeos...
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Article
Open AccessAssociation between oral health and cognitive function among Chinese older adults: the Taizhou imaging study
We aimed to investigate the association between oral health and cognitive function in a sample of older adults from a Chinese rural community.
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Article
Open AccessEngineering of NEMO as calcium indicators with large dynamics and high sensitivity
Genetically encoded calcium indicators (GECIs) are indispensable tools for real-time monitoring of intracellular calcium signals and cellular activities in living organisms. Current GECIs face the challenge of...
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Article
Open AccessAtomic mechanism of near threshold fatigue crack growth in vacuum
Structural failures resulting from prolonged low-amplitude loading are particularly problematic. Over the past century a succession of mechanisms have been hypothesized, as experimental validation has remained...
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Article
Open AccessPublisher Correction: Conservative route to genome compaction in a miniature annelid
A Correction to this paper has been published: https://doi.org/10.1038/s41559-020-01327-6.
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Article
Open AccessConservative route to genome compaction in a miniature annelid
The causes and consequences of genome reduction in animals are unclear because our understanding of this process mostly relies on lineages with often exceptionally high rates of evolution. Here, we decode the ...
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Chapter and Conference Paper
Designing Brittle Fracture Specimens to Investigate Environmentally Assisted Crack Growth
Subcritical crack growth can occur in a glass when the stress intensity factor is less than the fracture toughness if water molecules are present. A novel bi-material beam specimen is proposed to investigate e...