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    Article

    CGI1746 targets σ1R to modulate ferroptosis through mitochondria-associated membranes

    Ferroptosis is iron-dependent oxidative cell death. Labile iron and polyunsaturated fatty acid (PUFA)-containing lipids are two critical factors for ferroptosis execution. Many processes regulating iron homeos...

    Zili Zhang, Hong Zhou, Wenjia Gu, Yuehan Wei, Shan Mou in Nature Chemical Biology (2024)

  2. Article

    Open Access

    Association between oral health and cognitive function among Chinese older adults: the Taizhou imaging study

    We aimed to investigate the association between oral health and cognitive function in a sample of older adults from a Chinese rural community.

    Wenjia Gu, Jialin Li, Fei Li, Teck-Ek Ho, Yingzhe Wang in BMC Oral Health (2023)

  3. Article

    Open Access

    Engineering of NEMO as calcium indicators with large dynamics and high sensitivity

    Genetically encoded calcium indicators (GECIs) are indispensable tools for real-time monitoring of intracellular calcium signals and cellular activities in living organisms. Current GECIs face the challenge of...

    Jia Li, Ziwei Shang, Jia-Hui Chen, Wenjia Gu, Li Yao, **n Yang in Nature Methods (2023)

  4. Article

    Open Access

    Atomic mechanism of near threshold fatigue crack growth in vacuum

    Structural failures resulting from prolonged low-amplitude loading are particularly problematic. Over the past century a succession of mechanisms have been hypothesized, as experimental validation has remained...

    Mingjie Zhao, Wenjia Gu, Derek H. Warner in Nature Communications (2022)

  5. Article

    Open Access

    Publisher Correction: Conservative route to genome compaction in a miniature annelid

    A Correction to this paper has been published: https://doi.org/10.1038/s41559-020-01327-6.

    José M. Martín-Durán, Bruno C. Vellutini, Ferdinand Marlétaz in Nature Ecology & Evolution (2021)

  6. Article

    Open Access

    Conservative route to genome compaction in a miniature annelid

    The causes and consequences of genome reduction in animals are unclear because our understanding of this process mostly relies on lineages with often exceptionally high rates of evolution. Here, we decode the ...

    José M. Martín-Durán, Bruno C. Vellutini, Ferdinand Marlétaz in Nature Ecology & Evolution (2021)

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    Chapter and Conference Paper

    Designing Brittle Fracture Specimens to Investigate Environmentally Assisted Crack Growth

    Subcritical crack growth can occur in a glass when the stress intensity factor is less than the fracture toughness if water molecules are present. A novel bi-material beam specimen is proposed to investigate e...

    Sunday Aduloju, Wenjia Gu, Timothy Truster in Fracture, Fatigue, Failure and Damage Evol… (2018)